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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal CD4-positive T cell differentiation
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Accession:MP:0008076 term browser browse the term
Definition:atypical production of or inability to produce the subset of T lymphocytes that carry the CD4 marker, recognize intravesicular peptides bound to MHC class-II molecules, and turn on antibody production
Synonyms:exact_synonym: abnormal CD4+ T cell differentiation


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abnormal CD4-positive T cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptprk protein tyrosine phosphatase, receptor type, K IAGP RGD PMID:17434290 RGD:15036800 NCBI chr 1:16,738,896...17,236,687
Ensembl chr 1:18,558,365...19,056,107 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5432
    immune system phenotype 519
      abnormal immune system morphology 211
        abnormal immune system development 19
          abnormal leukopoiesis 16
            abnormal lymphopoiesis 16
              abnormal T cell differentiation 16
                abnormal CD4-positive T cell differentiation 2
                  abnormal T follicular helper cell differentiation 0
                  abnormal T-helper 1 cell differentiation 0
                  abnormal T-helper 2 cell differentiation 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5432
    immune system phenotype 519
      abnormal immune system morphology 211
        abnormal immune system cell morphology 150
          abnormal leukocyte morphology 150
            abnormal mononuclear cell morphology 125
              abnormal lymphocyte morphology 97
                abnormal T cell morphology 67
                  abnormal alpha-beta T cell morphology 32
                    abnormal CD4-positive, alpha beta T cell morphology 15
                      abnormal CD4-positive T cell differentiation 2
                        abnormal T follicular helper cell differentiation 0
                        abnormal T-helper 1 cell differentiation 0
                        abnormal T-helper 2 cell differentiation 0
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