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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:increased blastoma incidence
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Accession:MP:0008021 term browser browse the term
Definition:higher than normal incidence of a fast growing and invasive tumor composed chiefly or entirely of immature undifferentiated cells that have embryonic characteristics resembling the primordium of the organ in which the tumor arose
Synonyms:related_synonym: blastoma



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increased blastoma incidence term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:19808965 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,054,294
JBrowse link
G Smarcb1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 IAGP MGI PMID:16099835 NCBI chr10:75,732,603...75,757,448
Ensembl chr10:75,732,603...75,757,451
JBrowse link
G Yy1 YY1 transcription factor IAGP MGI PMID:26329601 NCBI chr12:108,758,841...108,786,074
Ensembl chr12:108,758,899...108,786,074
JBrowse link
increased glioblastoma incidence term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdkn2a cyclin dependent kinase inhibitor 2A IAGP MGI PMID:19196966 NCBI chr 4:89,192,710...89,212,856
Ensembl chr 4:89,192,708...89,212,890
JBrowse link
G Coro1c coronin, actin binding protein 1C IAGP MGI PMID:31677819 NCBI chr 5:113,980,500...114,046,767
Ensembl chr 5:113,980,497...114,046,819
JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:21625383 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,054,294
JBrowse link
G Nf1 neurofibromin 1 IAGP MGI PMID:10973261 NCBI chr11:79,223,541...79,472,435
Ensembl chr11:79,230,519...79,472,438
JBrowse link
G Pten phosphatase and tensin homolog IAGP MGI PMID:18948956 PMID:19196966 PMID:21625383 PMID:31677819 NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560
JBrowse link
G Trp53 transformation related protein 53 IAGP MGI PMID:10973261 PMID:18948956 PMID:21625383 PMID:31677819 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link
G Tyr tyrosinase IAGP MGI PMID:21625383 NCBI chr 7:87,073,979...87,142,637
Ensembl chr 7:87,073,979...87,142,720
JBrowse link
increased hepatoblastoma incidence term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctnnb1 catenin beta 1 IAGP MGI PMID:16951686 NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573
JBrowse link
G Rad50 RAD50 double strand break repair protein IAGP MGI PMID:24532689 NCBI chr11:53,540,346...53,598,146
Ensembl chr11:53,540,346...53,598,146
JBrowse link
G Rassf1 Ras association (RalGDS/AF-6) domain family member 1 IAGP MGI PMID:26980762 NCBI chr 9:107,428,752...107,439,460
Ensembl chr 9:107,428,754...107,439,466
JBrowse link
G Sav1 salvador family WW domain containing 1 IAGP MGI PMID:26980762 NCBI chr12:70,011,786...70,033,864
Ensembl chr12:70,011,786...70,033,776
JBrowse link
increased medulloblastoma incidence term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aicda activation-induced cytidine deaminase IAGP MGI PMID:19808965 NCBI chr 6:122,530,768...122,541,139
Ensembl chr 6:122,530,760...122,541,139
JBrowse link
G Brca2 breast cancer 2, early onset IAGP MGI PMID:19164512 NCBI chr 5:150,445,759...150,493,612
Ensembl chr 5:150,446,095...150,493,794
JBrowse link
G Cdkn1b cyclin dependent kinase inhibitor 1B IAGP MGI PMID:19147535 NCBI chr 6:134,897,364...134,902,488
Ensembl chr 6:134,897,364...134,902,476
JBrowse link
G Cdkn2c cyclin dependent kinase inhibitor 2C IAGP MGI PMID:16260494 PMID:19147535 NCBI chr 4:109,518,073...109,523,953
Ensembl chr 4:109,518,073...109,524,386
JBrowse link
G Ctnnb1 catenin beta 1 IAGP MGI PMID:22722829 NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573
JBrowse link
G Cxcr6 C-X-C motif chemokine receptor 6 IAGP MGI PMID:17413002 NCBI chr 9:123,635,542...123,640,819
Ensembl chr 9:123,635,540...123,640,825
JBrowse link
G Gli1 GLI-Kruppel family member GLI1 IAGP MGI PMID:18691547 NCBI chr10:127,165,751...127,177,448
Ensembl chr10:127,165,751...127,177,843
JBrowse link
G Gpr37l1 G protein-coupled receptor 37-like 1 IAGP MGI PMID:30452905 NCBI chr 1:135,087,988...135,095,419
Ensembl chr 1:135,087,972...135,095,419
JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:16015321 PMID:17047082 PMID:18691547 PMID:19064922 PMID:19808965 More... NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,054,294
JBrowse link
G Hk2 hexokinase 2 IAGP MGI PMID:24280485 NCBI chr 6:82,702,004...82,751,437
Ensembl chr 6:82,702,006...82,751,435
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 IAGP MGI PMID:19064922 NCBI chr  X:52,076,955...52,110,537
Ensembl chr  X:52,077,014...52,110,536
JBrowse link
G Lig4 ligase IV, DNA, ATP-dependent IAGP MGI PMID:16777961 PMID:19164512 PMID:20133615 NCBI chr 8:10,020,020...10,027,680
Ensembl chr 8:10,019,049...10,027,686
JBrowse link
G Mir34a microRNA 34a IAGP MGI PMID:25348795 NCBI chr 4:150,152,911...150,153,012
Ensembl chr 4:150,152,911...150,153,012
JBrowse link
G Nhej1 non-homologous end joining factor 1 IAGP MGI PMID:18775323 NCBI chr 1:75,006,505...75,101,870
Ensembl chr 1:75,006,298...75,101,844
JBrowse link
G Olig2 oligodendrocyte transcription factor 2 IAGP MGI PMID:18691547 NCBI chr16:91,016,745...91,025,567
Ensembl chr16:91,022,345...91,025,565
JBrowse link
G Pax7 paired box 7 IAGP MGI PMID:19213072 NCBI chr 4:139,464,357...139,560,841
Ensembl chr 4:139,464,373...139,560,839
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha IAGP MGI PMID:22722829 NCBI chr 3:32,451,203...32,520,256
Ensembl chr 3:32,451,820...32,522,635
JBrowse link
G Ptch1 patched 1 IAGP MGI PMID:9262482 PMID:9585239 PMID:12386820 PMID:16260494 PMID:16849540 More... NCBI chr13:63,656,142...63,721,274
Ensembl chr13:63,656,142...63,721,412
JBrowse link
G Ptch2 patched 2 IAGP MGI PMID:16849540 NCBI chr 4:116,953,253...116,973,298
Ensembl chr 4:116,953,272...116,973,298
JBrowse link
G Pten phosphatase and tensin homolog IAGP MGI PMID:27815386 NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560
JBrowse link
G Rag1 recombination activating 1 IAGP MGI PMID:16751807 NCBI chr 2:101,468,597...101,479,877
Ensembl chr 2:101,468,627...101,479,846
JBrowse link
G Rb1 RB transcriptional corepressor 1 IAGP MGI PMID:10783170 PMID:22574128 NCBI chr14:73,430,298...73,563,446
Ensembl chr14:73,421,113...73,563,262
JBrowse link
G Rtel1 regulator of telomere elongation helicase 1 IAGP MGI PMID:24115439 NCBI chr 2:180,961,504...180,998,409
Ensembl chr 2:180,961,532...180,998,409
JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling IAGP MGI PMID:17452975 NCBI chr19:46,385,335...46,477,243
Ensembl chr19:46,385,335...46,477,243
JBrowse link
G Tlx3 T cell leukemia, homeobox 3 IAGP MGI PMID:18691547 NCBI chr11:33,150,748...33,158,588
Ensembl chr11:33,150,752...33,153,589
JBrowse link
G Trim37 tripartite motif-containing 37 IAGP MGI PMID:27044324 NCBI chr11:87,017,675...87,141,700
Ensembl chr11:87,017,903...87,111,509
JBrowse link
G Trp53 transformation related protein 53 IAGP MGI PMID:9861017 PMID:10783170 PMID:16260494 PMID:16670198 PMID:16751807 More... NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link
G Xrcc1 X-ray repair complementing defective repair in Chinese hamster cells 1 IAGP MGI PMID:19633665 NCBI chr 7:24,246,124...24,272,863
Ensembl chr 7:24,245,714...24,272,865
JBrowse link
G Xrcc2 X-ray repair complementing defective repair in Chinese hamster cells 2 IAGP MGI PMID:16777961 PMID:19164512 NCBI chr 5:25,894,812...25,910,795
Ensembl chr 5:25,894,810...25,910,823
JBrowse link
G Xrcc4 X-ray repair complementing defective repair in Chinese hamster cells 4 IAGP MGI PMID:16670198 NCBI chr13:89,997,033...90,237,727
Ensembl chr13:89,922,146...90,237,727
JBrowse link
G Xrcc5 X-ray repair complementing defective repair in Chinese hamster cells 5 IAGP MGI PMID:16751807 NCBI chr 1:72,346,576...72,434,112
Ensembl chr 1:72,346,586...72,434,111
JBrowse link
increased neuroblastoma incidence term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alk anaplastic lymphoma kinase IAGP MGI PMID:24811913 PMID:29321660 PMID:31218818 NCBI chr17:72,174,206...72,911,719
Ensembl chr17:72,175,967...72,911,622
JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:23042116 PMID:25174395 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,054,294
JBrowse link
G Htatip2 HIV-1 Tat interactive protein 2 IAGP MGI PMID:14695192 NCBI chr 7:49,408,761...49,423,748
Ensembl chr 7:49,408,863...49,423,723
JBrowse link
G Nf1 neurofibromin 1 IAGP MGI PMID:9214616 PMID:10591653 PMID:25119042 NCBI chr11:79,223,541...79,472,435
Ensembl chr11:79,230,519...79,472,438
JBrowse link
G Rb1 RB transcriptional corepressor 1 IAGP MGI PMID:9214616 NCBI chr14:73,430,298...73,563,446
Ensembl chr14:73,421,113...73,563,262
JBrowse link
G Ret ret proto-oncogene IAGP MGI PMID:29321660 NCBI chr 6:118,128,709...118,174,705
Ensembl chr 6:118,128,706...118,174,679
JBrowse link
G Th tyrosine hydroxylase IAGP MGI PMID:22764207 NCBI chr 7:142,446,516...142,453,732
Ensembl chr 7:142,446,489...142,484,865
JBrowse link
G Trp53 transformation related protein 53 IAGP MGI PMID:9214616 PMID:10591653 PMID:25119042 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link
increased retinoblastoma incidence term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rb1 RB transcriptional corepressor 1 IAGP MGI PMID:15231717 PMID:17235288 PMID:17363591 NCBI chr14:73,430,298...73,563,446
Ensembl chr14:73,421,113...73,563,262
JBrowse link
G Rbl1 RB transcriptional corepressor like 1 IAGP MGI PMID:17235288 PMID:17363591 NCBI chr 2:156,987,813...157,046,454
Ensembl chr 2:156,987,813...157,046,454
JBrowse link
G Rbl2 RB transcriptional corepressor like 2 IAGP MGI PMID:15231717 PMID:17235288 NCBI chr 8:91,796,685...91,850,472
Ensembl chr 8:91,796,685...91,850,472
JBrowse link
G Trp53 transformation related protein 53 IAGP MGI PMID:17363591 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16699
    neoplasm 1340
      abnormal tumor susceptibility 1200
        abnormal tumor incidence 1179
          abnormal classified tumor incidence 750
            increased classified tumor incidence 733
              increased malignant tumor incidence 441
                increased blastoma incidence 46
                  increased glioblastoma incidence 7
                  increased hepatoblastoma incidence 4
                  increased medulloblastoma incidence 31
                  increased neuroblastoma incidence 8
                  increased renal hemangioblastoma incidence 0
                  increased retinoblastoma incidence 4
paths to the root