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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:increased systemic arterial systolic blood pressure
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Accession:MP:0006144 term browser browse the term
Definition:abnormal increase in the pressure in the arteries as the heart contracts and pumps blood into the arteries


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increased systemic arterial systolic blood pressure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Add1 adducin 1 IAGP RGD PMID:15474463 RGD:1302895 NCBI chr14:81,367,466...81,426,610
Ensembl chr14:81,367,468...81,426,496
JBrowse link
G Adora2b adenosine A2B receptor IMP RGD PMID:26385692 RGD:11533328 NCBI chr10:48,569,563...48,586,366
Ensembl chr10:48,569,555...48,586,365
JBrowse link
G Adora2bem2Mcwi adenosine A2B receptor; zinc finger nuclease induced mutant 2, Medical College of Wisconsin IMP RGD PMID:26385692 RGD:11533328
G Cyp11b1 cytochrome P450, family 11, subfamily b, polypeptide 1 IAGP RGD PMID:7981756 RGD:69709 NCBI chr 7:116,195,976...116,201,829 JBrowse link
G Ednra endothelin receptor type A IDA RGD PMID:16157796 RGD:1581830 NCBI chr19:33,928,356...33,991,703
Ensembl chr19:33,928,356...33,991,703
JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 IAGP DNA:duplication RGD PMID:20231529 RGD:11251783 NCBI chr19:57,660,194...57,701,158
Ensembl chr19:57,662,278...57,699,113
JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 IAGP DNA:deletion:exon (rat) RGD PMID:16368876 RGD:1581602 NCBI chr 1:216,293,087...216,630,339
Ensembl chr 1:216,293,087...216,630,339
JBrowse link
G Kcnq1dfk potassium voltage-gated channel subfamily Q member 1;deafness Kyoto IAGP RGD PMID:16368876 RGD:1581602
G Lepr leptin receptor onset IAGP
IMP
compared to SS/JrHsdMcwi RGD PMID:23154293, PMID:27465994 RGD:13432147, RGD:12911217 NCBI chr 5:120,503,475...120,682,281
Ensembl chr 5:120,564,645...120,682,221
JBrowse link
G Leprem2Mcwi leptin receptor; zinc finger nuclease induced mutant 2, Medical College of Wisconsin onset IMP compared to SS/JrHsdMcwi RGD PMID:27465994 RGD:12911217
G Leprfa leptin receptor; fa mutant IAGP RGD PMID:23154293 RGD:13432147
G Nppa natriuretic peptide A IMP as compared to the wild-type RGD PMID:24006081 RGD:8662415 NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705
JBrowse link
G Plod1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 IMP as compared to the wild-type RGD PMID:24006081 RGD:8662415 NCBI chr 5:164,720,629...164,747,071
Ensembl chr 5:164,720,587...164,747,083
JBrowse link
G Rarres2 retinoic acid receptor responder 2 sexual_dimorphism IMP compared to male wild-type RGD PMID:29906243, PMID:29906243 RGD:38596340, RGD:38596340 NCBI chr 4:78,205,809...78,208,956
Ensembl chr 4:78,205,812...78,208,767
JBrowse link
G Rarres2em1Msu retinoic acid receptor responder 2; CRISPR/Cas9 induced mutant 1, Msu sexual_dimorphism IMP compared to male wild-type RGD PMID:29906243, PMID:29906243 RGD:38596340, RGD:38596340

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  mammalian phenotype 5092
    cardiovascular system phenotype 1277
      abnormal cardiovascular system physiology 1063
        abnormal systemic arterial blood pressure 954
          increased systemic arterial blood pressure 612
            increased systemic arterial systolic blood pressure 127
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