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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:increased systemic arterial systolic blood pressure
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Accession:MP:0006144 term browser browse the term
Definition:abnormal increase in the pressure in the arteries as the heart contracts and pumps blood into the arteries


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increased systemic arterial systolic blood pressure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Add1 adducin 1 IAGP RGD PMID:15474463 RGD:1302895 NCBI chr14:80,333,242...80,401,641
Ensembl chr14:80,333,244...80,391,732 		JBrowse link
G Adora2b adenosine A2B receptor IMP RGD PMID:26385692 RGD:11533328 NCBI chr10:47,439,712...47,456,092
Ensembl chr10:47,439,701...47,456,091 		JBrowse link
G Adora2bem2Mcwi adenosine A2B receptor; zinc finger nuclease induced mutant 2, Medical College of Wisconsin IMP RGD PMID:26385692 RGD:11533328
G Alms1 ALMS1, centrosome and basal body associated protein exacerbates IMP compared to wild type RGD PMID:30385718 RGD:151361229 NCBI chr 4:119,683,085...119,783,471
Ensembl chr 4:119,683,076...119,783,471 		JBrowse link
G Alms1em1Mcwi Alstrom syndrome 1 homolog (human); zinc finger nuclease induced mutant 1, Medical College of Wisconsin exacerbates IMP compared to wild type RGD PMID:30385718 RGD:151361229
G Cyp11b1 cytochrome P450, family 11, subfamily b, polypeptide 1 IAGP RGD PMID:7981756 RGD:69709 NCBI chr 7:108,653,385...108,660,062
Ensembl chr 7:108,653,378...108,660,995
Ensembl chr 7:108,653,378...108,660,995 		JBrowse link
G Ednra endothelin receptor type A IDA RGD PMID:16157796 RGD:1581830 NCBI chr19:47,137,360...47,207,961
Ensembl chr19:47,137,771...47,201,284 		JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 IAGP DNA:duplication RGD PMID:20231529 RGD:11251783 NCBI chr19:69,765,276...69,804,681 JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 IAGP DNA:deletion:exon (rat) RGD PMID:16368876 RGD:1581602 NCBI chr 1:207,721,134...208,054,073
Ensembl chr 1:207,721,131...208,054,072 		JBrowse link
G Kcnq1dfk potassium voltage-gated channel subfamily Q member 1;deafness Kyoto IAGP RGD PMID:16368876 RGD:1581602
G Lepr leptin receptor onset
treatment 		IAGP
IMP 		compared to SS/JrHsdMcwi
compared to treated 		RGD PMID:23154293 PMID:27465994 PMID:33568522 RGD:13432147, RGD:12911217, RGD:401965412 NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:121,474,099...121,591,215 		JBrowse link
G Leprem2Mcwi leptin receptor; zinc finger nuclease induced mutant 2, Medical College of Wisconsin onset IMP compared to SS/JrHsdMcwi RGD PMID:27465994 RGD:12911217
G Leprfa leptin receptor; fa mutant IAGP RGD PMID:23154293 RGD:13432147
G Nppa natriuretic peptide A IMP as compared to the wild-type RGD PMID:24006081 RGD:8662415 NCBI chr 5:163,712,184...163,713,493
Ensembl chr 5:163,712,184...163,713,493 		JBrowse link
G Plod1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 IMP as compared to the wild-type RGD PMID:24006081 RGD:8662415 NCBI chr 5:163,623,847...163,650,737
Ensembl chr 5:163,623,848...163,651,110 		JBrowse link
G Rarres2 retinoic acid receptor responder 2 sexual_dimorphism IMP compared to male wild-type RGD PMID:29906243 PMID:29906243 RGD:38596340, RGD:38596340 NCBI chr 4:78,853,450...78,856,652
Ensembl chr 4:78,853,453...78,856,457 		JBrowse link
G Rarres2em1Msu retinoic acid receptor responder 2; CRISPR/Cas9 induced mutant 1, Msu sexual_dimorphism IMP compared to male wild-type RGD PMID:29906243 PMID:29906243 RGD:38596340, RGD:38596340
G Sod3 superoxide dismutase 3 onset IMP compared to SS/JrHsdMcwi RGD PMID:31972339 RGD:150573712 NCBI chr14:62,822,865...62,828,602
Ensembl chr14:62,811,177...62,829,125 		JBrowse link
G Sod3m1Mcwi superoxide dismutase 3; mutation 1, Medical College of Wisconsin onset IMP compared to SS/JrHsdMcwi RGD PMID:31972339 RGD:150573712
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Term Annotations click to browse term
  mammalian phenotype 5428
    cardiovascular system phenotype 1374
      abnormal cardiovascular system physiology 1152
        abnormal systemic arterial blood pressure 998
          increased systemic arterial blood pressure 639
            increased systemic arterial systolic blood pressure 138
paths to the root