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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:increased fat cell size
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Accession:MP:0006094 term browser browse the term
Definition:increased size of fat-storing cells found mostly in the abdominal cavity and subcutaneous tissue of mammals
Synonyms:exact_synonym: adipocyte hypertrophy;   fat cell hypertrophy
 related_synonym: lipocyte hypertrophy


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increased fat cell size term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lepr leptin receptor IMP RGD PMID:27225180, PMID:26537785 RGD:12910507, RGD:12911216 NCBI chr 5:120,503,475...120,682,281
Ensembl chr 5:120,564,645...120,682,221
JBrowse link
G Leprem3 leptin receptor; TALEN induced mutant 3 IMP RGD PMID:27225180 RGD:12910507
G Leprem4Lizh leptin receptor; CRISPR/Cas9 induced mutant 4, Lizh IMP RGD PMID:26537785 RGD:12911216
G Mc4r melanocortin 4 receptor IMP RGD PMID:21527895 RGD:6478803 NCBI chr18:62,612,838...62,614,725
Ensembl chr18:62,612,838...62,614,725
JBrowse link
G Mc4rm1Hubr melanocortin 4 receptor; ENU induced mutation 1, Hubr IMP RGD PMID:21527895 RGD:6478803

Term paths to the root
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Term Annotations click to browse term
  mammalian phenotype 5035
    adipose tissue phenotype 98
      abnormal adipose tissue morphology 92
        abnormal fat cell morphology 14
          increased fat cell size 12
            increased brown fat cell size 0
            increased white fat cell size 0
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