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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:increased susceptibility to graft versus host disease
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Accession:MP:0005672 term browser browse the term
Definition:greater likelihood of developing clinical symptoms of anorexia, diarrhea, loss of hair, leukopenia, thrombocytopenia, growth retardation, and eventual death brought about by the a graft versus host reaction, which is an immunological attack mounted by a graft against the host because of tissue incompatibility when immunologically competent cells are transplanted to an immunologically incompetent host
Synonyms:exact_synonym: decreased resistance to GVHD;   decreased resistance to graft versus host disease;   decreased resistance to graft vs host disease;   increased susceptibility to GVHD;   increased susceptibility to graft vs host disease



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  mammalian phenotype 5417
    immune system phenotype 498
      abnormal immune system physiology 384
        abnormal response to transplant 7
          increased susceptibility to graft versus host disease 0
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