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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:decreased circulating leptin level
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Accession:MP:0005668 term browser browse the term
Definition:less than the normal blood concentration of the peptide hormone secreted by white adipocytes and believed to regulate food intake and energy balance
Synonyms:exact_synonym: hypoleptinaemia;   hypoleptinemia;   reduced circulating leptin level



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decreased circulating leptin level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bscl2 BSCL2 lipid droplet biogenesis associated, seipin IMP RGD PMID:25934999 RGD:11085488 NCBI chr 1:205,731,828...205,743,430
Ensembl chr 1:205,733,872...205,743,421
JBrowse link
G Bscl2m1Kyo BSCL2, seipin lipid droplet biogenesis associated; ENU induced mutant1, Kyo IMP RGD PMID:25934999 RGD:11085488
G Ghsr growth hormone secretagogue receptor IMP RGD PMID:19931319 RGD:12910109 NCBI chr 2:110,268,489...110,271,865
Ensembl chr 2:110,268,489...110,271,865
JBrowse link
G Pmch pro-melanin-concentrating hormone IMP compared to wild-type RGD PMID:23555928 PMID:19934402 RGD:150429944, RGD:150429945 NCBI chr 7:22,511,934...22,513,250
Ensembl chr 7:22,511,934...22,513,250
JBrowse link
G Pmchm1Hubr pro-melanin-concentrating hormone; ENU induced mutant1, Hubr IMP compared to wild-type RGD PMID:23555928 PMID:19934402 RGD:150429944, RGD:150429945

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  mammalian phenotype 5417
    homeostasis/metabolism phenotype 1423
      abnormal homeostasis 1324
        abnormal hormone level 321
          abnormal circulating hormone level 290
            abnormal circulating leptin level 54
              decreased circulating leptin level 11
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