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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:increased cardiac muscle contractility
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Accession:MP:0005599 term browser browse the term
Definition:greater than the normal ability of the heart muscle to shorten or to develop increased tension, often measured by dP/dT max, fractional shortening (FS), velocity of circumferential fiber shortening (Vcfc), peak of aortic outflow velocity (PAV), and ventricular ejection fraction volume
Synonyms:exact_synonym: increased cardiac muscle contraction
 narrow_synonym: increased fractional shortening (FS);   increased peak of aortic outflow velocity (PAV);   increased velocity of circumferential fiber shortening (Vcfc);   increased velocity of circumferential fibre shortening (Vcfc);   increased ventricular ejection fraction volume
 alt_id: MP:0002973


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increased ventricle muscle contractility term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr2f2 nuclear receptor subfamily 2, group F, member 2 IMP compared to SS/JrHsdMcw RGD PMID:25687237 RGD:10401852 NCBI chr 1:131,447,671...131,465,749
Ensembl chr 1:131,448,447...131,460,473
JBrowse link
G Nr2f2em1Mcwi nuclear receptor subfamily 2, group F, member 2; zinc finger nuclease induced mutant 1, Medical College of Wisconsin IMP compared to SS/JrHsdMcw RGD PMID:25687237 RGD:10401852

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 4973
    cardiovascular system phenotype 1241
      abnormal cardiovascular system physiology 1038
        abnormal cardiac muscle contractility 17
          increased cardiac muscle contractility 8
            increased ventricle muscle contractility 3
Path 2
Term Annotations click to browse term
  mammalian phenotype 4973
    muscle phenotype 111
      abnormal muscle physiology 65
        abnormal muscle contractility 38
          abnormal cardiac muscle contractility 17
            increased cardiac muscle contractility 8
              increased ventricle muscle contractility 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.