increased susceptibility to type I hypersensitivity reaction - Ontology Report - Rat Genome Database

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MAMMALIAN PHENOTYPE - ANNOTATIONS	{{ watchLinkText }}
The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:	increased susceptibility to type I hypersensitivity reaction	go back to main search page
Accession:	MP:0005596	browse the term
Definition:	greater likelihood of developing a response manifested by localized or generalized reaction that occurs immediately (minutes) after exposure to an antigen to which the person/animal was previously sensitized; it is IgE-mediated, and mast cell activation and degranulation are hallmarks
Comment:	Examples of this type of hypersensitivity include hay fever, asthma, and anaphylaxis.
Synonyms:	exact_synonym:	decreased resistance to anaphylactic shock; decreased resistance to anaphylaxis; decreased resistance to immediate type hypersensitivity; decreased resistance to type I hypersensitivity reaction; increased susceptibility to allergic response; increased susceptibility to anaphylactic shock; increased susceptibility to anaphylaxis; increased susceptibility to immediate type hypersensitivity
	alt_id:	MP:0001878

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Term paths to the root

Path 1
Term	Annotations
mammalian phenotype	5374
immune system phenotype	492
abnormal immune system physiology	377
abnormal adaptive immunity	59
abnormal type I hypersensitivity reaction	0
increased susceptibility to type I hypersensitivity reaction	0
Path 2
Term	Annotations
mammalian phenotype	5374
immune system phenotype	492
abnormal immune system physiology	377
abnormal inflammatory response	228
abnormal acute inflammation	5
abnormal type I hypersensitivity reaction	0
increased susceptibility to type I hypersensitivity reaction	0

paths to the root