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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:decreased creatinine clearance
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Accession:MP:0005558 term browser browse the term
Definition:decreased rate of the process in which creatine is removed from the blood via renal filtration and its constituent parts degraded
Synonyms:exact_synonym: reduced creatinine clearance


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decreased creatinine clearance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 IMP compared to FHH RGD PMID:24722447 RGD:12910103 NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297
JBrowse link
G Nr4a1m1Mcwi nuclear receptor subfamily 4, group A, member 1; mutation 1, Medical College of Wisconsin IMP compared to FHH RGD PMID:24722447 RGD:12910103
G Trpc6 transient receptor potential cation channel, subfamily C, member 6 induces IMP compared to STZ-treated wild type RGD PMID:29923767 RGD:149735534 NCBI chr 8:5,759,387...5,864,000
Ensembl chr 8:5,758,935...5,828,092
JBrowse link
G Trpc6em1Mcwi transient receptor potential cation channel, subfamily C, member 6; CRISPR/Cas9 induced mutant 1, Medical College of Wisconsin induces IMP compared to STZ-treated wild type RGD PMID:29923767 RGD:149735534

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  mammalian phenotype 5190
    renal/urinary system phenotype 602
      abnormal renal/urinary system physiology 445
        abnormal kidney physiology 115
          abnormal renal filtration 41
            abnormal renal filtration rate 25
              decreased creatinine clearance 12
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