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The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories ( For more information about these ontologies, see the MGI Publications Page at

Term:decreased renal glomerular filtration rate
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Accession:MP:0005528 term browser browse the term
Definition:less than the normal volume of water filtered out of the plasma through glomerular capillary walls into the Bowman's capsule per unit time
Synonyms:exact_synonym: decreased GFR;   decreased kidney glomerular filtration rate;   reduced kidney glomerular filtration rate;   reduced renal glomerular filtration rate

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decreased renal glomerular filtration rate term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group) IAGP MGI PMID:32488095 NCBI chr 6:58,584,491...58,692,451
Ensembl chr 6:58,584,523...58,695,676
JBrowse link
G Adcy3 adenylate cyclase 3 IAGP MGI PMID:19174512 NCBI chr12:4,133,116...4,213,525
Ensembl chr12:4,133,103...4,213,525
JBrowse link
G Agtr1a angiotensin II receptor, type 1a IAGP MGI PMID:21459331 NCBI chr13:30,336,356...30,382,867
Ensembl chr13:30,336,441...30,382,867
JBrowse link
G Casp1 caspase 1 IAGP MGI PMID:15644489 NCBI chr 9:5,298,517...5,307,281
Ensembl chr 9:5,298,508...5,307,290
JBrowse link
G Casp4 caspase 4, apoptosis-related cysteine peptidase IAGP MGI PMID:15644489 NCBI chr 9:5,308,849...5,336,791
Ensembl chr 9:5,308,828...5,336,783
JBrowse link
G Clcnkb chloride channel, voltage-sensitive Kb IAGP MGI PMID:27421685 NCBI chr 4:141,404,357...141,416,055
Ensembl chr 4:141,404,353...141,416,014
JBrowse link
G Col4a3 collagen, type IV, alpha 3 IAGP MGI PMID:8947561 NCBI chr 1:82,586,921...82,722,059
Ensembl chr 1:82,586,921...82,722,059
JBrowse link
G Crim1 cysteine rich transmembrane BMP regulator 1 (chordin like) IAGP MGI PMID:17460146 NCBI chr17:78,200,233...78,376,592
Ensembl chr17:78,200,248...78,376,592
JBrowse link
G Dicer1 dicer 1, ribonuclease type III IAGP MGI PMID:25799508 NCBI chr12:104,687,740...104,751,968
Ensembl chr12:104,687,742...104,751,952
JBrowse link
G Gata5 GATA binding protein 5 IAGP MGI PMID:26617239 NCBI chr 2:180,325,088...180,335,503
Ensembl chr 2:180,325,133...180,334,699
JBrowse link
G Gnas GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus IAGP MGI PMID:16822937 NCBI chr 2:174,284,320...174,346,744
Ensembl chr 2:174,284,320...174,346,744
JBrowse link
G Hnf1a HNF1 homeobox A IAGP MGI PMID:8598044 NCBI chr 5:114,948,980...114,971,062
Ensembl chr 5:114,948,980...114,971,094
JBrowse link
G Hprt hypoxanthine guanine phosphoribosyl transferase IAGP MGI PMID:21459331 NCBI chr  X:52,988,078...53,021,660
Ensembl chr  X:52,988,137...53,021,659
JBrowse link
G Kcnj1 potassium inwardly-rectifying channel, subfamily J, member 1 IAGP MGI PMID:12122007 NCBI chr 9:32,372,418...32,399,197
Ensembl chr 9:32,372,493...32,399,197
JBrowse link
G Lepr leptin receptor IAGP MGI PMID:16971655 NCBI chr 4:101,717,137...101,815,352
Ensembl chr 4:101,717,404...101,815,352
JBrowse link
G Lgmn legumain IAGP MGI PMID:21292981 NCBI chr12:102,394,082...102,439,728
Ensembl chr12:102,394,084...102,439,813
JBrowse link
G Mmut methylmalonyl-Coenzyme A mutase IAGP MGI PMID:23898205 NCBI chr17:40,934,685...40,961,990
Ensembl chr17:40,934,685...40,961,988
JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell IAGP MGI PMID:16971655 NCBI chr 5:24,364,816...24,384,474
Ensembl chr 5:24,364,810...24,384,474
JBrowse link
G Pax8 paired box 8 IAGP MGI PMID:25799508 NCBI chr 2:24,420,551...24,475,599
Ensembl chr 2:24,420,560...24,475,599
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IAGP MGI PMID:11115063 NCBI chr 1:150,100,031...150,108,234
Ensembl chr 1:150,100,031...150,108,227
JBrowse link
G Ptpro protein tyrosine phosphatase, receptor type, O IAGP MGI PMID:11086029 NCBI chr 6:137,252,299...137,464,634
Ensembl chr 6:137,252,319...137,463,233
JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 IAGP MGI PMID:12417564 NCBI chr10:21,882,184...21,999,903
Ensembl chr10:21,882,184...21,999,903
JBrowse link
G Umod uromodulin IAGP MGI PMID:15522986 PMID:17264314 PMID:23748428 PMID:24324041 NCBI chr 7:119,462,708...119,479,262
Ensembl chr 7:119,462,711...119,479,282
JBrowse link
G Vegfa vascular endothelial growth factor A IAGP MGI PMID:12039984 NCBI chr17:46,016,993...46,032,377
Ensembl chr17:46,016,993...46,032,369
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 15816
    renal/urinary system phenotype 1906
      abnormal renal/urinary system physiology 892
        abnormal kidney physiology 520
          abnormal renal filtration 65
            abnormal renal glomerular filtration 40
              abnormal renal glomerular filtration rate 34
                decreased renal glomerular filtration rate 24
paths to the root