Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal T-helper 2 physiology
go back to main search page
Accession:MP:0005466 term browser browse the term
Definition:abnormal function of the type of T-helper cell whose cytokine production promotes defense against extracellular parasites and humoral immune responses typical of allergy
Synonyms:exact_synonym: T helper 2 functional abnormalities;   Th2 functional abnormalities;   abnormal T helper 2 function;   abnormal TH2 cell function;   abnormal helper T cell type 2 function;   abnormal helper T lymphocyte type 2 function


show annotations for term's descendants           Sort by:
abnormal T-helper 2 physiology term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf3 activating transcription factor 3 IAGP MGI PMID:18794337 NCBI chr 1:190,902,493...190,915,530
Ensembl chr 1:190,902,493...190,950,236 		JBrowse link
G Bcl6 B cell leukemia/lymphoma 6 IAGP MGI PMID:9171827 NCBI chr16:23,780,058...23,807,602
Ensembl chr16:23,783,802...23,807,602 		JBrowse link
G Btn2a2 butyrophilin, subfamily 2, member A2 IAGP MGI PMID:26809444 NCBI chr13:23,661,219...23,673,028
Ensembl chr13:23,661,846...23,673,027 		JBrowse link
G C3ar1 complement component 3a receptor 1 IAGP MGI PMID:12421977 NCBI chr 6:122,824,099...122,833,116
Ensembl chr 6:122,824,097...122,833,120 		JBrowse link
G Cbx5 chromobox 5 IAGP MGI PMID:22763435 NCBI chr15:103,099,973...103,148,337
Ensembl chr15:103,099,971...103,148,243 		JBrowse link
G Ccrl2 C-C motif chemokine receptor-like 2 IAGP MGI PMID:20606167 NCBI chr 9:110,883,902...110,886,586
Ensembl chr 9:110,883,554...110,886,587 		JBrowse link
G Cd276 CD276 antigen IAGP MGI PMID:26065426 NCBI chr 9:58,431,581...58,463,437
Ensembl chr 9:58,431,581...58,462,720 		JBrowse link
G Cd28 CD28 antigen IAGP MGI PMID:8808683 NCBI chr 1:60,785,547...60,812,521
Ensembl chr 1:60,755,959...60,812,518 		JBrowse link
G Cd4 CD4 antigen IAGP MGI PMID:11748274 NCBI chr 6:124,841,656...124,865,210
Ensembl chr 6:124,841,655...124,865,184 		JBrowse link
G Cd40lg CD40 ligand IAGP MGI PMID:7882172 NCBI chr  X:56,257,448...56,269,402
Ensembl chr  X:56,257,503...56,269,402 		JBrowse link
G Cd44 CD44 antigen IAGP MGI PMID:10859330 NCBI chr 2:102,641,486...102,732,014
Ensembl chr 2:102,641,486...102,732,010 		JBrowse link
G Cd81 CD81 antigen IAGP MGI PMID:9126932 PMID:9482907 NCBI chr 7:142,606,487...142,621,667
Ensembl chr 7:142,606,476...142,621,671 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta IAGP MGI PMID:7744000 NCBI chr 2:167,530,835...167,532,352
Ensembl chr 2:167,530,835...167,532,338 		JBrowse link
G Chi3l1 chitinase 3 like 1 IAGP MGI PMID:19414556 NCBI chr 1:134,109,894...134,117,769
Ensembl chr 1:134,109,914...134,117,919 		JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 IAGP MGI PMID:11801688 NCBI chr 1:74,193,153...74,200,405
Ensembl chr 1:74,193,150...74,200,405 		JBrowse link
G Dennd1b DENN domain containing 1B IAGP MGI PMID:26774822 NCBI chr 1:138,891,447...139,103,781
Ensembl chr 1:138,891,173...139,106,698 		JBrowse link
G Dicer1 dicer 1, ribonuclease type III IAGP MGI PMID:16009718 NCBI chr12:104,654,001...104,718,331
Ensembl chr12:104,654,001...104,718,211 		JBrowse link
G Dlg1 discs large MAGUK scaffold protein 1 IAGP MGI PMID:23028902 NCBI chr16:31,482,261...31,692,174
Ensembl chr16:31,482,261...31,693,947 		JBrowse link
G Ecm1 extracellular matrix protein 1 IAGP MGI PMID:21217760 NCBI chr 3:95,641,459...95,646,880
Ensembl chr 3:95,641,459...95,646,881 		JBrowse link
G Exph5 exophilin 5 IAGP MGI PMID:32240120 NCBI chr 9:53,212,814...53,292,466
Ensembl chr 9:53,212,970...53,288,814 		JBrowse link
G Fas Fas cell surface death receptor IAGP MGI PMID:6444324 PMID:16301622 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172 		JBrowse link
G Foxp3 forkhead box P3 IAGP MGI PMID:24135136 NCBI chr  X:7,445,915...7,461,482
Ensembl chr  X:7,439,883...7,461,484 		JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible 45 beta IAGP MGI PMID:14691480 NCBI chr10:80,765,925...80,768,038
Ensembl chr10:80,765,907...80,768,038 		JBrowse link
G Gfi1 growth factor independent 1 transcription repressor IAGP MGI PMID:17116877 NCBI chr 5:107,864,521...107,873,671
Ensembl chr 5:107,864,523...107,873,902 		JBrowse link
G Gpr84 G protein-coupled receptor 84 IAGP MGI PMID:15993493 NCBI chr15:103,216,660...103,219,050
Ensembl chr15:103,216,662...103,219,039 		JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:16230473 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,055,336 		JBrowse link
G Icos inducible T cell co-stimulator IAGP MGI PMID:11343121 NCBI chr 1:60,999,909...61,039,481
Ensembl chr 1:61,017,086...61,039,479 		JBrowse link
G Icosl icos ligand IAGP MGI PMID:14615582 NCBI chr10:77,904,921...77,915,359
Ensembl chr10:77,905,136...77,919,747 		JBrowse link
G Ifngr2 interferon gamma receptor 2 IAGP MGI PMID:11118001 NCBI chr16:91,343,947...91,360,895
Ensembl chr16:91,343,960...91,362,511 		JBrowse link
G Il10 interleukin 10 IAGP MGI PMID:18375937 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711 		JBrowse link
G Il13 interleukin 13 IAGP MGI PMID:10330435 NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529 		JBrowse link
G Il13ra1 interleukin 13 receptor, alpha 1 IAGP MGI PMID:18066066 NCBI chr  X:35,375,761...35,434,915
Ensembl chr  X:35,375,763...35,434,912 		JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 IAGP MGI PMID:10727469 NCBI chr 1:40,444,105...40,504,575
Ensembl chr 1:40,468,730...40,504,575 		JBrowse link
G Il21r interleukin 21 receptor IAGP MGI PMID:16778988 PMID:17077330 NCBI chr 7:125,202,424...125,232,742
Ensembl chr 7:125,202,601...125,232,742 		JBrowse link
G Il27ra interleukin 27 receptor, alpha IAGP MGI PMID:16301622 PMID:18375937 NCBI chr 8:84,756,915...84,769,250
Ensembl chr 8:84,756,923...84,769,218 		JBrowse link
G Il33 interleukin 33 IAGP MGI PMID:22331917 NCBI chr19:29,902,513...29,938,118
Ensembl chr19:29,902,514...29,938,118 		JBrowse link
G Il4 interleukin 4 IAGP MGI PMID:8906833 PMID:10330435 PMID:12150890 PMID:16547221 PMID:19682930 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496 		JBrowse link
G Il4ra interleukin 4 receptor, alpha IAGP MGI PMID:9380721 PMID:19770271 NCBI chr 7:125,151,443...125,178,646
Ensembl chr 7:125,151,292...125,178,646 		JBrowse link
G Il6 interleukin 6 IAGP MGI PMID:8666893 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Itch itchy, E3 ubiquitin protein ligase IAGP MGI PMID:24135136 NCBI chr 2:154,975,401...155,068,775
Ensembl chr 2:154,975,429...155,068,775 		JBrowse link
G Itk IL2 inducible T cell kinase IAGP MGI PMID:16547221 NCBI chr11:46,215,975...46,280,342
Ensembl chr11:46,215,977...46,280,342 		JBrowse link
G Jund jun D proto-oncogene IAGP MGI PMID:15029240 NCBI chr 8:71,150,389...71,153,265
Ensembl chr 8:71,151,599...71,153,265 		JBrowse link
G Lat linker for activation of T cells IAGP MGI PMID:16887989 PMID:18209052 PMID:19682930 NCBI chr 7:125,962,999...125,968,877
Ensembl chr 7:125,962,996...125,968,742 		JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 IAGP MGI PMID:17137798 NCBI chr18:38,551,960...38,598,250
Ensembl chr18:38,543,449...38,598,356 		JBrowse link
G Nfatc1 nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1 IAGP MGI PMID:9462518 NCBI chr18:80,649,418...80,756,286
Ensembl chr18:80,649,420...80,756,286 		JBrowse link
G Nfatc2 nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 IAGP MGI PMID:14573689 NCBI chr 2:168,318,330...168,443,900
Ensembl chr 2:168,318,330...168,443,577 		JBrowse link
G Nfatc2ip nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 interacting protein IAGP MGI PMID:20133688 NCBI chr 7:125,982,025...125,995,909
Ensembl chr 7:125,982,026...125,995,909 		JBrowse link
G Nlrp10 NLR family, pyrin domain containing 10 IAGP MGI PMID:22538615 NCBI chr 7:108,521,060...108,529,365
Ensembl chr 7:108,521,059...108,529,385 		JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 IAGP MGI PMID:20884616 NCBI chr11:93,840,640...93,847,082
Ensembl chr11:93,840,640...93,847,085 		JBrowse link
G Pawr PRKC, apoptosis, WT1, regulator IAGP MGI PMID:12970181 NCBI chr10:108,168,050...108,250,708
Ensembl chr10:108,167,982...108,250,101 		JBrowse link
G Pcgf2 polycomb group ring finger 2 IAGP MGI PMID:11520462 NCBI chr11:97,579,647...97,593,260
Ensembl chr11:97,579,649...97,591,323 		JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma IAGP MGI PMID:10669416 NCBI chr12:32,223,128...32,258,675
Ensembl chr12:32,223,472...32,258,658 		JBrowse link
G Pirb paired Ig-like receptor B IAGP MGI PMID:12021780 NCBI chr 7:3,715,504...3,723,381
Ensembl chr 7:3,714,408...3,723,390 		JBrowse link
G Pou2af1 POU domain, class 2, associating factor 1 IAGP MGI PMID:17568779 NCBI chr 9:51,124,990...51,151,379
Ensembl chr 9:51,125,008...51,151,380 		JBrowse link
G Prkcq protein kinase C, theta IAGP MGI PMID:15528385 NCBI chr 2:11,176,922...11,306,033
Ensembl chr 2:11,176,919...11,306,033 		JBrowse link
G Rad50 RAD50 double strand break repair protein IAGP MGI PMID:15608641 PMID:20483988 NCBI chr11:53,540,346...53,598,146
Ensembl chr11:53,540,346...53,598,146 		JBrowse link
G Retnla resistin like alpha IAGP MGI PMID:19349464 NCBI chr16:48,662,972...48,664,824
Ensembl chr16:48,662,914...48,664,824 		JBrowse link
G Rgs16 regulator of G-protein signaling 16 IAGP MGI PMID:22593615 NCBI chr 1:153,616,099...153,621,212
Ensembl chr 1:153,616,095...153,621,214 		JBrowse link
G Rhog ras homolog family member G IAGP MGI PMID:14701744 NCBI chr 7:101,888,330...101,899,325
Ensembl chr 7:101,888,330...101,905,261 		JBrowse link
G Samsn1 SAM domain, SH3 domain and nuclear localization signals, 1 IAGP MGI PMID:19923443 NCBI chr16:75,655,682...75,706,154
Ensembl chr16:75,655,681...75,819,169 		JBrowse link
G Slamf6 SLAM family member 6 IAGP MGI PMID:15879084 NCBI chr 1:171,745,002...171,776,525
Ensembl chr 1:171,745,082...171,780,737 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 IEA MGI NCBI chr 1:52,158,588...52,201,024
Ensembl chr 1:52,158,599...52,201,024 		JBrowse link
G Stat4 signal transducer and activator of transcription 4 IAGP MGI PMID:8700209 NCBI chr 1:52,026,265...52,146,348
Ensembl chr 1:52,026,307...52,146,348 		JBrowse link
G Stat6 signal transducer and activator of transcription 6 IAGP MGI PMID:8602263 NCBI chr10:127,478,855...127,496,856
Ensembl chr10:127,478,855...127,496,826 		JBrowse link
G Stim2 stromal interaction molecule 2 IAGP MGI PMID:18327260 NCBI chr 5:54,155,865...54,278,399
Ensembl chr 5:54,155,841...54,278,399 		JBrowse link
G Suv39h1 suppressor of variegation 3-9 1 IAGP MGI PMID:22763435 NCBI chr  X:7,927,401...7,940,994
Ensembl chr  X:7,927,410...7,940,999 		JBrowse link
G Tlr4 toll-like receptor 4 IAGP MGI PMID:15684036 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521 		JBrowse link
G Tnfrsf21 tumor necrosis factor receptor superfamily, member 21 IAGP MGI PMID:11485735 PMID:11714751 NCBI chr17:43,327,446...43,400,079
Ensembl chr17:43,327,446...43,400,080 		JBrowse link
G Tnfrsf4 tumor necrosis factor receptor superfamily, member 4 IAGP MGI PMID:11157058 NCBI chr 4:156,098,049...156,101,070
Ensembl chr 4:156,098,300...156,101,069 		JBrowse link
G Trim27 tripartite motif-containing 27 IAGP MGI PMID:22128329 NCBI chr13:21,363,570...21,378,893
Ensembl chr13:21,363,615...21,378,894 		JBrowse link
G Tslp thymic stromal lymphopoietin IAGP MGI PMID:23437132 NCBI chr18:32,948,436...32,952,852
Ensembl chr18:32,948,436...32,952,850 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 17065
    immune system phenotype 5763
      abnormal immune system physiology 3496
        abnormal immune cell physiology 1829
          abnormal leukocyte physiology 1793
            abnormal lymphocyte physiology 1315
              abnormal T cell physiology 778
                abnormal CD4-positive, alpha-beta T cell physiology 196
                  abnormal T-helper 2 physiology 71
paths to the root