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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal T-helper 1 physiology
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Accession:MP:0005465 term browser browse the term
Definition:abnormal function of the type of T-helper cell whose cytokine production favors cellular immune responses and delayed type hypersensitivity
Synonyms:exact_synonym: T helper 1 functional abnormalities;   Th1 functional abnormalities;   abnormal T helper 1 function;   abnormal TH1 cell function;   abnormal helper T cell type 1 function;   abnormal helper T lymphocyte type 1 function


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abnormal T-helper 1 physiology term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahnak AHNAK nucleoprotein IAGP MGI PMID:18191595 NCBI chr19:8,966,640...9,054,299
Ensembl chr19:8,966,648...9,054,278 		JBrowse link
G Aire autoimmune regulator IAGP MGI PMID:21182094 NCBI chr10:77,865,856...77,879,444
Ensembl chr10:77,865,856...77,879,444 		JBrowse link
G Btn2a2 butyrophilin, subfamily 2, member A2 IAGP MGI PMID:26809444 NCBI chr13:23,661,219...23,673,028
Ensembl chr13:23,661,846...23,673,027 		JBrowse link
G Cd247 CD247 antigen IAGP MGI PMID:9529325 NCBI chr 1:165,607,514...165,698,722
Ensembl chr 1:165,616,250...165,704,846 		JBrowse link
G Cd276 CD276 antigen IAGP MGI PMID:12925852 PMID:26065426 NCBI chr 9:58,431,581...58,463,437
Ensembl chr 9:58,431,581...58,462,720 		JBrowse link
G Cd28 CD28 antigen IAGP MGI PMID:8808683 NCBI chr 1:60,785,547...60,812,521
Ensembl chr 1:60,755,959...60,812,518 		JBrowse link
G Cd44 CD44 antigen IAGP MGI PMID:10859330 NCBI chr 2:102,641,486...102,732,014
Ensembl chr 2:102,641,486...102,732,010 		JBrowse link
G Cd74 CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) IAGP MGI PMID:11937578 NCBI chr18:60,936,921...60,945,724
Ensembl chr18:60,936,920...60,945,724 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta IAGP MGI PMID:7744000 PMID:17911624 NCBI chr 2:167,530,835...167,532,352
Ensembl chr 2:167,530,835...167,532,338 		JBrowse link
G Ciita class II transactivator IAGP MGI PMID:11937578 NCBI chr16:10,297,877...10,348,928
Ensembl chr16:10,297,923...10,346,282 		JBrowse link
G Crtam cytotoxic and regulatory T cell molecule IAGP MGI PMID:18329370 NCBI chr 9:40,880,987...40,915,922
Ensembl chr 9:40,880,987...40,915,924 		JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 IAGP MGI PMID:11801688 NCBI chr 1:74,193,153...74,200,405
Ensembl chr 1:74,193,150...74,200,405 		JBrowse link
G Dicer1 dicer 1, ribonuclease type III IAGP MGI PMID:16009718 NCBI chr12:104,654,001...104,718,331
Ensembl chr12:104,654,001...104,718,211 		JBrowse link
G Dlg1 discs large MAGUK scaffold protein 1 IAGP MGI PMID:23028902 NCBI chr16:31,482,261...31,692,174
Ensembl chr16:31,482,261...31,693,947 		JBrowse link
G Fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide IAGP MGI PMID:9529325 NCBI chr 1:171,057,141...171,061,918
Ensembl chr 1:171,057,141...171,061,934 		JBrowse link
G Flt3l FMS-like tyrosine kinase 3 ligand IAGP MGI PMID:22615130 NCBI chr 7:44,780,607...44,785,914
Ensembl chr 7:44,779,212...44,785,856 		JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible 45 beta IAGP MGI PMID:14691480 PMID:16287712 NCBI chr10:80,765,925...80,768,038
Ensembl chr10:80,765,907...80,768,038 		JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible 45 gamma IAGP MGI PMID:11371360 NCBI chr13:52,000,711...52,002,511
Ensembl chr13:52,000,714...52,002,504 		JBrowse link
G Gkn2 gastrokine 2 IAGP MGI PMID:26974160 NCBI chr 6:87,350,347...87,356,476
Ensembl chr 6:87,350,339...87,356,479 		JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:16230473 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,055,336 		JBrowse link
G H2-DMa histocompatibility 2, class II, locus DMa IAGP MGI PMID:11937578 NCBI chr17:34,338,667...34,358,075
Ensembl chr17:34,338,515...34,358,075 		JBrowse link
G Il10 interleukin 10 IAGP MGI PMID:18375937 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711 		JBrowse link
G Il12b interleukin 12b IAGP MGI PMID:9529155 NCBI chr11:44,290,890...44,305,504
Ensembl chr11:44,290,890...44,304,860 		JBrowse link
G Il18 interleukin 18 IAGP MGI PMID:9529155 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140 		JBrowse link
G Il18r1 interleukin 18 receptor 1 IAGP MGI PMID:10227969 NCBI chr 1:40,504,712...40,540,014
Ensembl chr 1:40,504,712...40,540,014 		JBrowse link
G Il20rb interleukin 20 receptor beta IAGP MGI PMID:19124723 NCBI chr 9:100,339,772...100,368,526
Ensembl chr 9:100,339,772...100,368,841 		JBrowse link
G Il21r interleukin 21 receptor IAGP MGI PMID:17077330 NCBI chr 7:125,202,424...125,232,742
Ensembl chr 7:125,202,601...125,232,742 		JBrowse link
G Il27ra interleukin 27 receptor, alpha IAGP MGI PMID:11672539 PMID:15585875 PMID:17118967 PMID:18375937 NCBI chr 8:84,756,915...84,769,250
Ensembl chr 8:84,756,923...84,769,218 		JBrowse link
G Il6 interleukin 6 IAGP MGI PMID:8666893 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Irf5 interferon regulatory factor 5 IAGP MGI PMID:15665823 NCBI chr 6:29,526,129...29,541,874
Ensembl chr 6:29,526,624...29,541,870 		JBrowse link
G Map3k4 mitogen-activated protein kinase kinase kinase 4 IAGP MGI PMID:15044949 NCBI chr17:12,446,508...12,537,683
Ensembl chr17:12,446,508...12,537,683 		JBrowse link
G Mapk14 mitogen-activated protein kinase 14 IAGP MGI PMID:19011223 NCBI chr17:28,910,316...28,967,379
Ensembl chr17:28,910,303...28,967,380 		JBrowse link
G Mog myelin oligodendrocyte glycoprotein IAGP MGI PMID:14624757 NCBI chr17:37,321,632...37,334,290
Ensembl chr17:37,321,635...37,334,290 		JBrowse link
G Mpz myelin protein zero IAGP MGI PMID:12616486 NCBI chr 1:170,978,282...170,988,699
Ensembl chr 1:170,978,280...170,988,699 		JBrowse link
G Myd88 myeloid differentiation primary response gene 88 IAGP MGI PMID:24439266 NCBI chr 9:119,165,000...119,169,084
Ensembl chr 9:119,165,000...119,170,477 		JBrowse link
G Nfatc2 nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 IAGP MGI PMID:14573689 NCBI chr 2:168,318,330...168,443,900
Ensembl chr 2:168,318,330...168,443,577 		JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 IAGP MGI PMID:20884616 NCBI chr11:93,840,640...93,847,082
Ensembl chr11:93,840,640...93,847,085 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 IAGP MGI PMID:19139201 NCBI chr 8:89,373,943...89,415,103
Ensembl chr 8:89,373,943...89,415,102 		JBrowse link
G Nos2 nitric oxide synthase 2, inducible IAGP MGI PMID:7539113 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080 		JBrowse link
G Npy1r neuropeptide Y receptor Y1 IAGP MGI PMID:16330815 NCBI chr 8:67,149,595...67,159,452
Ensembl chr 8:67,149,844...67,159,444 		JBrowse link
G Pdlim2 PDZ and LIM domain 2 IAGP MGI PMID:15963787 NCBI chr14:70,401,667...70,415,140
Ensembl chr14:70,401,667...70,415,130 		JBrowse link
G Pou2af1 POU domain, class 2, associating factor 1 IAGP MGI PMID:17568779 NCBI chr 9:51,124,990...51,151,379
Ensembl chr 9:51,125,008...51,151,380 		JBrowse link
G Ptx3 pentraxin related gene IAGP MGI PMID:12432394 NCBI chr 3:66,127,308...66,133,227
Ensembl chr 3:66,127,331...66,133,226 		JBrowse link
G Rad50 RAD50 double strand break repair protein IAGP MGI PMID:20483988 NCBI chr11:53,540,346...53,598,146
Ensembl chr11:53,540,346...53,598,146 		JBrowse link
G Rag2 recombination activating gene 2 IAGP MGI PMID:17081782 NCBI chr 2:101,455,057...101,462,873
Ensembl chr 2:101,455,063...101,462,874 		JBrowse link
G Rcan1 regulator of calcineurin 1 IAGP MGI PMID:12925851 NCBI chr16:92,188,839...92,263,057
Ensembl chr16:92,188,841...92,267,755 		JBrowse link
G Rgs16 regulator of G-protein signaling 16 IAGP MGI PMID:22593615 NCBI chr 1:153,616,099...153,621,212
Ensembl chr 1:153,616,095...153,621,214 		JBrowse link
G Ripk2 receptor (TNFRSF)-interacting serine-threonine kinase 2 IAGP MGI PMID:11894098 NCBI chr 4:16,122,740...16,163,674
Ensembl chr 4:16,122,733...16,163,647 		JBrowse link
G Samsn1 SAM domain, SH3 domain and nuclear localization signals, 1 IAGP MGI PMID:19923443 NCBI chr16:75,655,682...75,706,154
Ensembl chr16:75,655,681...75,819,169 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 IAGP MGI PMID:12571365 NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366 		JBrowse link
G Stat4 signal transducer and activator of transcription 4 IAGP MGI PMID:8700209 NCBI chr 1:52,026,265...52,146,348
Ensembl chr 1:52,026,307...52,146,348 		JBrowse link
G Stim2 stromal interaction molecule 2 IAGP MGI PMID:18327260 NCBI chr 5:54,155,865...54,278,399
Ensembl chr 5:54,155,841...54,278,399 		JBrowse link
G Tlr9 toll-like receptor 9 IAGP MGI PMID:11130078 NCBI chr 9:106,099,797...106,104,075
Ensembl chr 9:106,099,797...106,104,082 		JBrowse link
G Tnfrsf21 tumor necrosis factor receptor superfamily, member 21 IAGP MGI PMID:11485735 NCBI chr17:43,327,446...43,400,079
Ensembl chr17:43,327,446...43,400,080 		JBrowse link
G Trim27 tripartite motif-containing 27 IAGP MGI PMID:22128329 NCBI chr13:21,363,570...21,378,893
Ensembl chr13:21,363,615...21,378,894 		JBrowse link
G Tyk2 tyrosine kinase 2 IAGP MGI PMID:11313413 NCBI chr 9:21,015,364...21,042,689
Ensembl chr 9:21,015,364...21,042,539 		JBrowse link
G Usp15 ubiquitin specific peptidase 15 IAGP MGI PMID:27721430 NCBI chr10:122,940,911...123,032,924
Ensembl chr10:122,940,911...123,032,900 		JBrowse link
G Zbtb46 zinc finger and BTB domain containing 46 IAGP MGI PMID:22615130 NCBI chr 2:181,012,105...181,134,776
Ensembl chr 2:181,029,555...181,101,219 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 17065
    immune system phenotype 5763
      abnormal immune system physiology 3496
        abnormal immune cell physiology 1829
          abnormal leukocyte physiology 1793
            abnormal lymphocyte physiology 1315
              abnormal T cell physiology 778
                abnormal CD4-positive, alpha-beta T cell physiology 196
                  abnormal T-helper 1 physiology 58
paths to the root