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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:cardiovascular system phenotype
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Accession:MP:0005385 term browser browse the term
Definition:the observable morphological and physiological characteristics of the mammalian heart, blood vessels, or circulatory system that are manifested through development and lifespan
Synonyms:narrow_synonym: Abnormality of the cardiovascular system
 xref: HP:0001626



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abnormal aorta morphology term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E IMP RGD PMID:29166645 RGD:150520219 NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Apoeem1Ejt apolipoprotein E; TALEN induced mutant 1, Ejt IMP RGD PMID:29166645 RGD:150520219
G Apoeem1Sage apolipoprotein E; endonuclease induced mutant 1, Sigma Advanced Genetic Engineering Labs IMP RGD PMID:29166645 RGD:150520219
abnormal aortic valve flow term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lepr leptin receptor IAGP DNA:mutations:cds: : (rat) RGD PMID:32710530 RGD:401960103 NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
abnormal aortic valve morphology term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lepr leptin receptor IAGP DNA:mutations:cds: : (rat) RGD PMID:32710530 RGD:401960103 NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
abnormal blood-brain barrier function term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A IMP RGD PMID:22049154 RGD:8657330 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcb1aem2Sage ATP binding cassette subfamily B member 1A; ZFN induced mutant 2, Sage IMP RGD PMID:22049154 RGD:8657330
G Abcc2 ATP binding cassette subfamily C member 2 IAGP RGD PMID:12663688 RGD:704399 NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Crh corticotropin releasing hormone IDA RGD PMID:12663088 RGD:704425 NCBI chr 2:104,059,184...104,061,048
Ensembl chr 2:102,143,055...102,144,919
JBrowse link
abnormal blood-cerebrospinal fluid barrier function term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tmem67 transmembrane protein 67 IAGP RGD PMID:30705305 RGD:14995942 NCBI chr 5:30,333,793...30,386,702
Ensembl chr 5:25,536,458...25,589,334
JBrowse link
G Tmem67wpk transmembrane protein 67; wpk mutant IAGP RGD PMID:30705305 RGD:14995942
abnormal cardiac muscle contractility term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ttn titin IAGP RGD PMID:27869827 RGD:11565821 NCBI chr 3:82,059,648...82,332,130
Ensembl chr 3:61,652,439...61,924,741
JBrowse link
G Ttnem1Sage Titin; zinc finger nuclease induced mutant 1,Sigma Advanced Genetic Engineering Labs IAGP RGD PMID:27869827 RGD:11565821
G Ttnem2Sage Titin; zinc finger nuclease induced mutant 2,Sigma Advanced Genetic Engineering Labs IAGP RGD PMID:27869827 RGD:11565821
abnormal cardiac muscle relaxation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnnt2 troponin T2, cardiac type IDA RGD PMID:10946062 RGD:1580434 NCBI chr13:49,819,123...49,837,125
Ensembl chr13:47,267,204...47,285,388
JBrowse link
abnormal cardiovascular system physiology term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 IAGP DNA:deletion:exon (rat) RGD PMID:16368876 RGD:1581602 NCBI chr 1:207,721,134...208,054,073
Ensembl chr 1:198,291,766...198,624,669
JBrowse link
G Kcnq1dfk potassium voltage-gated channel subfamily Q member 1;deafness Kyoto IAGP RGD PMID:16368876 RGD:1581602
abnormal choroid vasculature morphology term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd36 CD36 molecule IAGP RGD PMID:18288886 RGD:2307226 NCBI chr 4:18,209,088...18,302,142
Ensembl chr 4:17,354,466...17,513,903
JBrowse link
abnormal circadian regulation of systemic arterial blood pressure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Astn1 astrotactin 1 IMP RGD PMID:24714719 RGD:12792227 NCBI chr13:73,070,754...73,388,902
Ensembl chr13:70,537,703...70,855,440
JBrowse link
G Brinp2 BMP/retinoic acid inducible neural specific 2 IMP RGD PMID:24714719 RGD:12792227 NCBI chr13:72,964,498...73,065,312
Ensembl chr13:70,431,010...70,531,810
JBrowse link
G Cop1 COP1, E3 ubiquitin ligase IMP RGD PMID:24714719 RGD:12792227 NCBI chr13:73,954,058...74,095,283
Ensembl chr13:71,429,961...71,538,890
JBrowse link
G Pappa2 pappalysin 2 IMP RGD PMID:24714719 RGD:12792227 NCBI chr13:73,407,385...73,683,699
Ensembl chr13:70,876,794...71,147,779
JBrowse link
G Tnr tenascin R IMP RGD PMID:24714719 RGD:12792227 NCBI chr13:74,285,141...74,706,174
Ensembl chr13:72,091,585...72,167,641
JBrowse link
abnormal heart echocardiography feature term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dmd dystrophin IMP RGD PMID:25310701 RGD:12880034 NCBI chr  X:51,070,098...53,437,845
Ensembl chr  X:47,272,331...49,504,207
JBrowse link
G Dmdem1Ang dystrophin; TALEN-induced mutant1, Ang IMP RGD PMID:25310701 RGD:12880034
abnormal heart left ventricle pressure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lepr leptin receptor treatment IAGP RGD PMID:33568522 RGD:401965412 NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
abnormal myocardial fiber calcium currents term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myh7b myosin heavy chain 7B IMP RGD PMID:32207065 RGD:126925946 NCBI chr 3:164,537,211...164,582,441
Ensembl chr 3:144,098,190...144,122,084
JBrowse link
G Myh7bem1Blar myosin heavy chain 7B; CRISPR/Cas9 induced mutant 1, Blar IMP RGD PMID:32207065 RGD:126925946
abnormal retina blood vessel morphology term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gla galactosidase, alpha IMP RGD PMID:31253878 RGD:401976417 NCBI chr  X:102,062,497...102,073,915
Ensembl chr  X:97,768,996...97,780,664
JBrowse link
G Glaem2Mcwi galactosidase, alpha; CRISPR/Cas9 system induced mutant 2, Medical College of Wisconsin IMP RGD PMID:31253878 RGD:401976417
G Lrp5 LDL receptor related protein 5 IMP RGD PMID:32833527 RGD:40902996 NCBI chr 1:210,243,499...210,346,886
Ensembl chr 1:200,814,250...200,917,581
JBrowse link
G Lrp5em1Vari LDL receptor related protein 5;CRISPR/Cas9 induced mutant 1, Vari IMP RGD PMID:32833527 RGD:40902996
G Lrp5em2Vari LDL receptor related protein 5; CRISPR/Cas9 induced mutant 2, Vari IMP RGD PMID:32833527 RGD:40902996
G Lrp5em3Vari LDL receptor related protein 5; CRISPR/Cas9 induced mutant 3, Vari IMP RGD PMID:32833527 RGD:40902996
abnormal retina blood vessel pattern term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrp5 LDL receptor related protein 5 IMP RGD PMID:32833527 RGD:40902996 NCBI chr 1:210,243,499...210,346,886
Ensembl chr 1:200,814,250...200,917,581
JBrowse link
G Lrp5em1Vari LDL receptor related protein 5;CRISPR/Cas9 induced mutant 1, Vari IMP RGD PMID:32833527 RGD:40902996
G Lrp5em2Vari LDL receptor related protein 5; CRISPR/Cas9 induced mutant 2, Vari IMP RGD PMID:32833527 RGD:40902996
G Lrp5em3Vari LDL receptor related protein 5; CRISPR/Cas9 induced mutant 3, Vari IMP RGD PMID:32833527 RGD:40902996
G Pde6b phosphodiesterase 6B IMP compared to wild-type RGD PMID:31009522 RGD:40924664 NCBI chr14:1,468,302...1,511,435
Ensembl chr14:1,323,310...1,366,450
JBrowse link
G Pde6bem1Baek phosphodiesterase 6B; Cpf1-CRISPR induced mutant1, Baek IMP compared to wild-type RGD PMID:31009522 RGD:40924664
abnormal retina vasculature morphology term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cryba1 crystallin, beta A1 IMP RGD PMID:17931883 RGD:2303652 NCBI chr10:63,106,465...63,113,020
Ensembl chr10:62,608,383...62,614,726
JBrowse link
G Cryba1Nuc1Dbsa crystallin, beta A1;Nuc1 mutant, Dbsa IMP RGD PMID:17931883 RGD:2303652
G Kdr kinase insert domain receptor IDA inhibition significantly reduces retinal neovascularization RGD PMID:15951738 RGD:1581593 NCBI chr14:32,572,031...32,615,204
Ensembl chr14:32,217,871...32,261,018
JBrowse link
abnormal vascular development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cryba1 crystallin, beta A1 IAGP DNA:insertion:exon RGD PMID:17931883 RGD:2303652 NCBI chr10:63,106,465...63,113,020
Ensembl chr10:62,608,383...62,614,726
JBrowse link
abnormal vascular wound healing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Spon2 spondin 2 IMP RGD PMID:25751394 RGD:329328927 NCBI chr14:81,713,070...81,742,510
Ensembl chr14:77,511,901...77,517,996
JBrowse link
G Spon2em1Holi spondin 2; TALEN induced mutant1, Holi IMP RGD PMID:25751394 RGD:329328927
abnormal vasodilation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpr182 G protein-coupled receptor 182 IDA RGD PMID:7592696 RGD:61533 NCBI chr 7:65,471,254...65,474,110
Ensembl chr 7:63,578,750...63,589,210
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 IMP RGD PMID:26637559 RGD:11344212 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfe2l2em1Mcwi nuclear factor, erythroid 2-like 2; TALEN induced mutant 1, Medical College of Wisconsin IMP RGD PMID:26637559 RGD:11344212
G Sod3 superoxide dismutase 3 IMP DNA:missense mutation:CDS:p.E124D RGD PMID:24322611 RGD:38548929 NCBI chr14:62,822,865...62,828,602
Ensembl chr14:58,609,958...58,615,990
JBrowse link
G Sod3m1Mcwi superoxide dismutase 3; mutation 1, Medical College of Wisconsin IMP RGD PMID:24322611 RGD:38548929
absent ductus venosus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor IMP RGD PMID:23859880 RGD:13204753 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Ahrem2Sage aryl hydrocarbon receptor; ZFN induced mutant2, Sage IMP RGD PMID:23859880 RGD:13204753
arteriosclerosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lepr leptin receptor IAGP DNA:mutations:cds: : (rat) RGD PMID:10901178 RGD:401965414 NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
calcified artery term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mgp matrix Gla protein IDA RGD PMID:17138823 RGD:2293588 NCBI chr 4:171,497,472...171,500,888
Ensembl chr 4:169,766,279...169,769,667
JBrowse link
cardiac fibrosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myh7b myosin heavy chain 7B IMP RGD PMID:32207065 RGD:126925946 NCBI chr 3:164,537,211...164,582,441
Ensembl chr 3:144,098,190...144,122,084
JBrowse link
G Myh7bem1Blar myosin heavy chain 7B; CRISPR/Cas9 induced mutant 1, Blar IMP RGD PMID:32207065 RGD:126925946
cardiac hypertrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crebbp CREB binding protein IDA RGD PMID:12477714 RGD:1298794 NCBI chr10:11,842,307...11,968,266
Ensembl chr10:11,335,953...11,461,888
JBrowse link
G Ep300 E1A binding protein p300 IDA RGD PMID:12477714 RGD:1298794 NCBI chr 7:114,987,857...115,058,652
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088
JBrowse link
G Igf1 insulin-like growth factor 1 IDA RGD PMID:15996002 RGD:1580474 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Nppb natriuretic peptide B IMP RGD PMID:26063669 RGD:12910116 NCBI chr 5:163,699,955...163,701,314
Ensembl chr 5:158,416,866...158,418,168
JBrowse link
G Nppbem2Mcwi natriuretic peptide B; zinc finger nuclease induced mutant 2, Medical College of Wisconsin IMP RGD PMID:26063669 RGD:12910116
G Npr2 natriuretic peptide receptor 2 IAGP RGD PMID:16537417 RGD:1601488 NCBI chr 5:62,678,197...62,697,360
Ensembl chr 5:57,883,171...57,901,580
JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha IDA RGD PMID:16799071 RGD:1580700 NCBI chr 2:227,839,058...228,113,560
Ensembl chr 2:225,165,766...225,438,974
JBrowse link
G Ppp3cb protein phosphatase 3 catalytic subunit beta IDA RGD PMID:16496058 RGD:1580703 NCBI chr15:3,809,182...3,854,204
Ensembl chr15:3,760,030...3,804,981
JBrowse link
G Rcan1 regulator of calcineurin 1 IDA RGD PMID:15899894 RGD:1581475 NCBI chr11:45,108,123...45,188,065
Ensembl chr11:31,622,210...31,702,045
JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 IMP RGD PMID:11549339 RGD:1357201 NCBI chr 2:206,309,715...206,314,070
Ensembl chr 2:203,621,587...203,629,681
JBrowse link
G test test1 TAS RGD PMID:12446719 RGD:629553
cardiac interstitial fibrosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ubd ubiquitin D IMP associated with induced myocardial infarction RGD PMID:29438664 RGD:126925221 NCBI chr20:1,390,734...1,392,685
Ensembl chr20:1,385,864...1,408,639
Ensembl chr20:1,385,864...1,408,639
JBrowse link
G Ubdem1 ubiquitin D; CRISPR/Cas9 induced mutant1 IMP associated with induced myocardial infarction RGD PMID:29438664 RGD:126925221
G Zbtb16 zinc finger and BTB domain containing 16 ameliorates IMP RGD PMID:28396530 RGD:150340623 NCBI chr 8:57,885,886...58,073,507
Ensembl chr 8:48,994,566...49,177,011
JBrowse link
G Zbtb16em1Ipcv zinc finger and BTB domain containing 16; TALEN induced mutant 1, Ipcv ameliorates IMP RGD PMID:28396530 RGD:150340623
decreased angiogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr1a angiotensin II receptor, type 1a induces IMP RGD PMID:32324784 RGD:127345089 NCBI chr17:34,383,397...34,435,523
Ensembl chr17:34,174,429...34,226,946
JBrowse link
G Agtr1aem5Mcwi angiotensin II receptor, type 1a; zinc finger nuclease induced mutant 5, Medical College of Wisconsin induces IMP RGD PMID:32324784 RGD:127345089
G Wars2 tryptophanyl tRNA synthetase 2 (mitochondrial) IMP RGD PMID:27389904 RGD:127338472 NCBI chr 2:186,459,744...186,543,581
Ensembl chr 2:186,459,444...186,543,571
JBrowse link
decreased cardiac muscle contractility term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gla galactosidase, alpha onset IMP compared to Wild type RGD PMID:29979634 RGD:401976416 NCBI chr  X:102,062,497...102,073,915
Ensembl chr  X:97,768,996...97,780,664
JBrowse link
G Glaem2Mcwi galactosidase, alpha; CRISPR/Cas9 system induced mutant 2, Medical College of Wisconsin onset IMP compared to Wild type RGD PMID:29979634 RGD:401976416
G Ubd ubiquitin D IMP associated with induced myocardial infarction RGD PMID:29438664 RGD:126925221 NCBI chr20:1,390,734...1,392,685
Ensembl chr20:1,385,864...1,408,639
Ensembl chr20:1,385,864...1,408,639
JBrowse link
G Ubdem1 ubiquitin D; CRISPR/Cas9 induced mutant1 IMP associated with induced myocardial infarction RGD PMID:29438664 RGD:126925221
decreased cardiac muscle relaxation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ttn titin IAGP RGD PMID:27869827 RGD:11565821 NCBI chr 3:82,059,648...82,332,130
Ensembl chr 3:61,652,439...61,924,741
JBrowse link
G Ttnem1Sage Titin; zinc finger nuclease induced mutant 1,Sigma Advanced Genetic Engineering Labs IAGP RGD PMID:27869827 RGD:11565821
G Ttnem2Sage Titin; zinc finger nuclease induced mutant 2,Sigma Advanced Genetic Engineering Labs IAGP RGD PMID:27869827 RGD:11565821
decreased cardiac stroke volume term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ttn titin IAGP RGD PMID:27869827 RGD:11565821 NCBI chr 3:82,059,648...82,332,130
Ensembl chr 3:61,652,439...61,924,741
JBrowse link
G Ttnem2Sage Titin; zinc finger nuclease induced mutant 2,Sigma Advanced Genetic Engineering Labs IAGP RGD PMID:27869827 RGD:11565821
decreased coronary flow rate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wars2 tryptophanyl tRNA synthetase 2 (mitochondrial) IMP RGD PMID:27389904 RGD:127338472 NCBI chr 2:186,459,744...186,543,581
Ensembl chr 2:186,459,444...186,543,571
JBrowse link
decreased heart left ventricle wall thickness term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gla galactosidase, alpha onset IMP compared to Wild type RGD PMID:29979634 RGD:401976416 NCBI chr  X:102,062,497...102,073,915
Ensembl chr  X:97,768,996...97,780,664
JBrowse link
G Glaem2Mcwi galactosidase, alpha; CRISPR/Cas9 system induced mutant 2, Medical College of Wisconsin onset IMP compared to Wild type RGD PMID:29979634 RGD:401976416
decreased heart left ventricle weight term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Camk2n1 calcium/calmodulin-dependent protein kinase II inhibitor 1 IMP RGD PMID:31327268 RGD:18899561 NCBI chr 5:155,958,116...155,959,897
Ensembl chr 5:150,673,507...150,676,600
JBrowse link
G Camk2n1em1Tja calcium/calmodulin-dependent protein kinase II inhibitor 1; ZFN induced mutant 1, Tja IMP RGD PMID:31327268 RGD:18899561
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 IAGP RGD PMID:11832364 RGD:727991 NCBI chr 7:108,719,349...108,726,024
Ensembl chr 7:106,838,590...106,845,004
JBrowse link
decreased heart rate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnj16 potassium inwardly-rectifying channel, subfamily J, member 16 IMP compared to SS/JrHsdMcwi RGD PMID:28931751 RGD:38500204 NCBI chr10:96,489,329...96,520,745
Ensembl chr10:95,960,725...96,021,702
JBrowse link
G Kcnj16em1Mcwi potassium inwardly-rectifying channel, subfamily J, member 16; zinc finger nuclease induced mutant 1, Medical College of Wisconsin IMP compared to SS/JrHsdMcwi RGD PMID:28931751 RGD:38500204
G Mc4r melanocortin 4 receptor IMP compared with WI-MC4r^m1Hubr RGD PMID:24400148 PMID:24400148 RGD:13825242, RGD:13825242 NCBI chr18:62,689,798...62,691,685
Ensembl chr18:60,419,832...60,421,719
JBrowse link
G Mc4rm1Hubr melanocortin 4 receptor; ENU induced mutation 1, Hubr IMP compared with WI-MC4r^m1Hubr RGD PMID:24400148 PMID:24400148 RGD:13825242, RGD:13825242
G Rarres2 retinoic acid receptor responder 2 sexual_dimorphism IMP compared to male wild-type RGD PMID:29906243 PMID:29906243 RGD:38596340, RGD:38596340 NCBI chr 4:78,853,450...78,856,652
Ensembl chr 4:77,522,535...77,525,556
JBrowse link
G Rarres2em1Msu retinoic acid receptor responder 2; CRISPR/Cas9 induced mutant 1, Msu sexual_dimorphism IMP compared to male wild-type RGD PMID:29906243 PMID:29906243 RGD:38596340, RGD:38596340
G Tnf tumor necrosis factor IAGP RGD PMID:9590569 RGD:1357163 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629
JBrowse link
decreased heart ventricle muscle contractility term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il36rn interleukin 36 receptor antagonist IMP RGD PMID:32048631 RGD:126925167 NCBI chr 3:27,442,679...27,449,306
Ensembl chr 3:7,044,406...7,051,016
JBrowse link
G Il36rntm1(Myh6-cre)Mhzh interleukin 36 receptor antagonist; tm1, Mhzh IMP RGD PMID:32048631 RGD:126925167
G Sh2b3 SH2B adaptor protein 3 IMP RGD PMID:25628389 RGD:12904914 NCBI chr12:40,391,755...40,414,336
Ensembl chr12:34,731,911...34,753,616
JBrowse link
G Sh2b3em2Mcwi SH2B adaptor protein 3; zinc finger nuclease induced mutant 2, Medical College of Wisconsin IMP RGD PMID:25628389 RGD:12904914
decreased heart weight term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clcn6 chloride voltage-gated channel 6 IMP as compared to the wild-type RGD PMID:24006081 RGD:8662415 NCBI chr 5:158,434,299...158,465,174
Ensembl chr 5:158,434,299...158,465,059
JBrowse link
G Dmd dystrophin IMP RGD PMID:25310701 RGD:12880034 NCBI chr  X:51,070,098...53,437,845
Ensembl chr  X:47,272,331...49,504,207
JBrowse link
G Dmdem1Ang dystrophin; TALEN-induced mutant1, Ang IMP RGD PMID:25310701 RGD:12880034
G Nppc natriuretic peptide C IMP compared to wild type RGD PMID:29566041 RGD:127284867 NCBI chr 9:94,767,986...94,772,186
Ensembl chr 9:87,320,051...87,324,251
JBrowse link
G Nppcem3Kyo natriuretic peptide C; ZFN induced mutant 3, Kyo IMP compared to wild type RGD PMID:29566041 RGD:127284867
G test test1 TAS fr str61106 RGD PMID:9453331 RGD:619652
decreased left ventricle developed pressure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ttn titin IAGP RGD PMID:27869827 RGD:11565821 NCBI chr 3:82,059,648...82,332,130
Ensembl chr 3:61,652,439...61,924,741
JBrowse link
G Ttnem2Sage Titin; zinc finger nuclease induced mutant 2,Sigma Advanced Genetic Engineering Labs IAGP RGD PMID:27869827 RGD:11565821
decreased left ventricle systolic pressure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il36rn interleukin 36 receptor antagonist IMP RGD PMID:32048631 RGD:126925167 NCBI chr 3:27,442,679...27,449,306
Ensembl chr 3:7,044,406...7,051,016
JBrowse link
G Il36rntm1(Myh6-cre)Mhzh interleukin 36 receptor antagonist; tm1, Mhzh IMP RGD PMID:32048631 RGD:126925167
decreased mean systemic arterial blood pressure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmal1 basic helix-loop-helix ARNT like 1 IMP compared to wild type RGD PMID:32306766 RGD:155598602 NCBI chr 1:176,766,222...176,864,741
Ensembl chr 1:167,331,633...167,430,231
JBrowse link
G Bmal1em1Mcwi basic helix-loop-helix ARNT like 1;CRISPR/Cas9 induced mutant 1,Mcwi IMP compared to wild type RGD PMID:32306766 RGD:155598602
G Cd247 Cd247 molecule induced IMP compared to wild-type RGD PMID:24343121 PMID:24343121 RGD:13442481, RGD:13442481 NCBI chr13:80,576,264...80,651,422
Ensembl chr13:78,043,307...78,122,263
JBrowse link
G Cd247em1Mcwi Cd247 molecule; zinc finger nuclease induced mutant 1, Medical College of Wisconsin induced IMP compared to wild-type RGD PMID:24343121 PMID:24343121 RGD:13442481, RGD:13442481
G Cd36 CD36 molecule IMP RGD PMID:22128087 RGD:6893560 NCBI chr 4:18,209,088...18,302,142
Ensembl chr 4:17,354,466...17,513,903
JBrowse link
G Clcn6 chloride voltage-gated channel 6 IMP as compared to the wild-type RGD PMID:24006081 RGD:8662415 NCBI chr 5:158,434,299...158,465,174
Ensembl chr 5:158,434,299...158,465,059
JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 IMP compared to wild type SS rat RGD PMID:30354811 RGD:39939000 NCBI chr12:20,331,073...20,336,527
Ensembl chr12:15,217,442...15,221,889
JBrowse link
G Gper1em1Bj G protein-coupled estrogen receptor 1; CRISPR/Cas 9 induced mutant 1, Bj IMP compared to wild type SS rat RGD PMID:30354811 RGD:39939000
G Hvcn1 hydrogen voltage-gated channel 1 IMP RGD PMID:24935944 RGD:14985214 NCBI chr12:34,341,673...34,370,010
Ensembl chr12:34,335,190...34,370,141
JBrowse link
G Mc4r melanocortin 4 receptor IMP RGD PMID:24400148 RGD:13825242 NCBI chr18:62,689,798...62,691,685
Ensembl chr18:60,419,832...60,421,719
JBrowse link
G Mc4rm1Hubr melanocortin 4 receptor; ENU induced mutation 1, Hubr IMP RGD PMID:24400148 RGD:13825242
G Nox4 NADPH oxidase 4 induced IMP compared to SS/JrHsdMcwi RGD PMID:26644237 PMID:26644237 RGD:11085830, RGD:11085830 NCBI chr 1:150,313,736...150,491,480
Ensembl chr 1:140,901,097...141,077,406
JBrowse link
G Nox4em2Mcwi NADPH oxidase 4; zinc finger nuclease induced mutant 2, Medical College of Wisconsin induced IMP compared to SS/JrHsdMcwi RGD PMID:26644237 PMID:26644237 RGD:11085830, RGD:11085830
G P2rx7 purinergic receptor P2X 7 IMP RGD PMID:31630543 RGD:14995937 NCBI chr12:39,550,531...39,594,984
Ensembl chr12:33,879,745...33,934,619
JBrowse link
G Rarres2 retinoic acid receptor responder 2 sexual_dimorphism IMP compared to female wild-type RGD PMID:29906243 PMID:29906243 RGD:38596340, RGD:38596340 NCBI chr 4:78,853,450...78,856,652
Ensembl chr 4:77,522,535...77,525,556
JBrowse link
G Rarres2em1Msu retinoic acid receptor responder 2; CRISPR/Cas9 induced mutant 1, Msu sexual_dimorphism IMP compared to female wild-type RGD PMID:29906243 PMID:29906243 RGD:38596340, RGD:38596340
G Ren renin sexual_dimorphism IMP compared to wild type
compared to wild type male
RGD PMID:21242461 PMID:21242461 RGD:7771614, RGD:7771614 NCBI chr13:47,348,312...47,359,539
Ensembl chr13:44,796,091...44,807,489
JBrowse link
G Renem1Mcwi renin; zinc finger nuclease induced mutant 1, Medical College of Wisconsin sexual_dimorphism IMP compared to wild type
compared to wild type male
RGD PMID:21242461 PMID:21242461 RGD:7771614, RGD:7771614
decreased myocardial fiber size term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zbtb16 zinc finger and BTB domain containing 16 IMP compared to wild type SHR/OlaIpcv; RGD PMID:28396530 RGD:150340623 NCBI chr 8:57,885,886...58,073,507
Ensembl chr 8:48,994,566...49,177,011
JBrowse link
G Zbtb16em1Ipcv zinc finger and BTB domain containing 16; TALEN induced mutant 1, Ipcv IMP compared to wild type SHR/OlaIpcv; RGD PMID:28396530 RGD:150340623
decreased pulmonary artery pressure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc39a12 solute carrier family 39 member 12 IMP RGD PMID:26258299 RGD:10401832 NCBI chr17:82,262,303...82,348,974
Ensembl chr17:77,353,805...77,440,353
JBrowse link
G Slc39a12em77Tja solute carrier family 39 (zinc transporter), member 12; zinc finger nuclease induced mutant 77, Timothy J. Aitman IMP RGD PMID:26258299 RGD:10401832
decreased pulse pressure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gper1 G protein-coupled estrogen receptor 1 IMP compared to wild type SS rat RGD PMID:30354811 RGD:39939000 NCBI chr12:20,331,073...20,336,527
Ensembl chr12:15,217,442...15,221,889
JBrowse link
G Gper1em1Bj G protein-coupled estrogen receptor 1; CRISPR/Cas 9 induced mutant 1, Bj IMP compared to wild type SS rat RGD PMID:30354811 RGD:39939000
decreased renal plasma flow rate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lepr leptin receptor IAGP DNA:mutations::cds: : (rat) RGD PMID:10901178 RGD:401965414 NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
decreased susceptibility to hypertension term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnj1 potassium inwardly-rectifying channel, subfamily J, member 1 IMP RGD PMID:23753405 RGD:13782272 NCBI chr 8:39,014,822...39,066,716
Ensembl chr 8:30,753,617...30,813,796
JBrowse link
G Kcnj1em1Kasu potassium voltage-gated channel subfamily J member 1; ZFN induced mutant 1,Kasu IMP RGD PMID:23753405 RGD:13782272
G Ncf2 neutrophil cytosolic factor 2 induces IMP compared to wild-type littermates RGD PMID:22326221 PMID:22326221 RGD:9587793, RGD:9587793 NCBI chr13:67,505,492...67,536,015
Ensembl chr13:64,955,503...64,986,277
JBrowse link
G Ncf2em1Mcwi neutrophil cytosolic factor 2; zinc finger nuclease induced mutant 1,Mcwi induces IMP compared to wild-type littermates RGD PMID:22326221 PMID:22326221 RGD:9587793, RGD:9587793
G Nox4 NADPH oxidase 4 induced IMP compared to SS/JrHsdMcwi RGD PMID:26644237 PMID:26644237 RGD:11085830, RGD:11085830 NCBI chr 1:150,313,736...150,491,480
Ensembl chr 1:140,901,097...141,077,406
JBrowse link
G Nox4em2Mcwi NADPH oxidase 4; zinc finger nuclease induced mutant 2, Medical College of Wisconsin induced IMP compared to SS/JrHsdMcwi RGD PMID:26644237 PMID:26644237 RGD:11085830, RGD:11085830
G Plekha7 pleckstrin homology domain containing A7 IMP compared to wild type RGD PMID:25136115 PMID:25136115 RGD:11079199, RGD:11079199 NCBI chr 1:179,798,856...179,982,155
Ensembl chr 1:170,365,135...170,547,775
JBrowse link
G Plekha7em4Mcwi pleckstrin homology domain containing, family A member 7; zinc finger nuclease induced mutant 4, Medical College of Wisconsin IMP compared to wild type RGD PMID:25136115 PMID:25136115 RGD:11079199, RGD:11079199
G Sh2b3 SH2B adaptor protein 3 IMP RGD PMID:25776069 RGD:13442483 NCBI chr12:40,391,755...40,414,336
Ensembl chr12:34,731,911...34,753,616
JBrowse link
G Sh2b3em1Mcwi SH2B adaptor protein 3; zinc finger nuclease induced mutant 1, Medical College of Wisconsin IMP RGD PMID:25776069 RGD:13442483
decreased systemic arterial blood pressure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts16 ADAM metallopeptidase with thrombospondin type 1 motif, 16 IAGP DNA:polymorphism RGD PMID:19423552 RGD:2312639 NCBI chr 1:34,258,899...34,388,952
Ensembl chr 1:32,430,436...32,560,494
JBrowse link
G Hmox1 heme oxygenase 1 IDA RGD PMID:12215473 RGD:1580453 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hvcn1 hydrogen voltage-gated channel 1 IMP RGD PMID:24935944 RGD:14985214 NCBI chr12:34,341,673...34,370,010
Ensembl chr12:34,335,190...34,370,141
JBrowse link
G Kcnj16 potassium inwardly-rectifying channel, subfamily J, member 16 IMP compared to SS/JrHsdMcwi RGD PMID:28931751 RGD:38500204 NCBI chr10:96,489,329...96,520,745
Ensembl chr10:95,960,725...96,021,702
JBrowse link
G Kcnj16em1Mcwi potassium inwardly-rectifying channel, subfamily J, member 16; zinc finger nuclease induced mutant 1, Medical College of Wisconsin IMP compared to SS/JrHsdMcwi RGD PMID:28931751 RGD:38500204
decreased systemic arterial diastolic blood pressure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts16 ADAM metallopeptidase with thrombospondin type 1 motif, 16 IMP As compared to SS parents RGD PMID:23185005 RGD:9685162 NCBI chr 1:34,258,899...34,388,952
Ensembl chr 1:32,430,436...32,560,494
JBrowse link
G Adamts16em1Bj ADAM metallopeptidase with thrombospondin type 1 motif, 16; ZFN mutant1,Bj IMP As compared to SS parents RGD PMID:23185005 RGD:9685162
G Bmal1 basic helix-loop-helix ARNT like 1 IMP compared to wild type RGD PMID:32306766 RGD:155598602 NCBI chr 1:176,766,222...176,864,741
Ensembl chr 1:167,331,633...167,430,231
JBrowse link
G Bmal1em1Mcwi basic helix-loop-helix ARNT like 1;CRISPR/Cas9 induced mutant 1,Mcwi IMP compared to wild type RGD PMID:32306766 RGD:155598602
G Camk2n1 calcium/calmodulin-dependent protein kinase II inhibitor 1 IMP RGD PMID:31327268 RGD:18899561 NCBI chr 5:155,958,116...155,959,897
Ensembl chr 5:150,673,507...150,676,600
JBrowse link
G Camk2n1em1Tja calcium/calmodulin-dependent protein kinase II inhibitor 1; ZFN induced mutant 1, Tja IMP RGD PMID:31327268 RGD:18899561
G Clcn6 chloride voltage-gated channel 6 IMP as compared to the wild-type RGD PMID:24006081 RGD:8662415 NCBI chr 5:158,434,299...158,465,174
Ensembl chr 5:158,434,299...158,465,059
JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 IMP compared to wild type SS rat RGD PMID:30354811 RGD:39939000 NCBI chr12:20,331,073...20,336,527
Ensembl chr12:15,217,442...15,221,889
JBrowse link
G Gper1em1Bj G protein-coupled estrogen receptor 1; CRISPR/Cas 9 induced mutant 1, Bj IMP compared to wild type SS rat RGD PMID:30354811 RGD:39939000
G Rarres2 retinoic acid receptor responder 2 sexual_dimorphism IMP compared to female wild-type RGD PMID:29906243 PMID:29906243 RGD:38596340, RGD:38596340 NCBI chr 4:78,853,450...78,856,652
Ensembl chr 4:77,522,535...77,525,556
JBrowse link
G Rarres2em1Msu retinoic acid receptor responder 2; CRISPR/Cas9 induced mutant 1, Msu sexual_dimorphism IMP compared to female wild-type RGD PMID:29906243 PMID:29906243 RGD:38596340, RGD:38596340
G Ren renin sexual_dimorphism IMP compared to wild type
compared to wild type male
RGD PMID:21242461 PMID:21242461 RGD:7771614, RGD:7771614 NCBI chr13:47,348,312...47,359,539
Ensembl chr13:44,796,091...44,807,489
JBrowse link
G Renem1Mcwi renin; zinc finger nuclease induced mutant 1, Medical College of Wisconsin sexual_dimorphism IMP compared to wild type male RGD PMID:21242461 PMID:21242461 RGD:7771614, RGD:7771614
G test test1 TAS
IDA
fr str628908
fr str61106wastas
RGD PMID:9453331 PMID:9453331 RGD:619652, RGD:619652
decreased systemic arterial systolic blood pressure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts16 ADAM metallopeptidase with thrombospondin type 1 motif, 16 IMP As compared to SS parents RGD PMID:23185005 RGD:9685162 NCBI chr 1:34,258,899...34,388,952
Ensembl chr 1:32,430,436...32,560,494
JBrowse link
G Adamts16em1Bj ADAM metallopeptidase with thrombospondin type 1 motif, 16; ZFN mutant1,Bj IMP As compared to SS parents RGD PMID:23185005 RGD:9685162
G Bmal1 basic helix-loop-helix ARNT like 1 IMP compared to wild type RGD PMID:32306766 RGD:155598602 NCBI chr 1:176,766,222...176,864,741
Ensembl chr 1:167,331,633...167,430,231
JBrowse link
G Bmal1em1Mcwi basic helix-loop-helix ARNT like 1;CRISPR/Cas9 induced mutant 1,Mcwi IMP compared to wild type RGD PMID:32306766 RGD:155598602
G Camk2n1 calcium/calmodulin-dependent protein kinase II inhibitor 1 IMP RGD PMID:31327268 RGD:18899561 NCBI chr 5:155,958,116...155,959,897
Ensembl chr 5:150,673,507...150,676,600
JBrowse link
G Camk2n1em1Tja calcium/calmodulin-dependent protein kinase II inhibitor 1; ZFN induced mutant 1, Tja IMP RGD PMID:31327268 RGD:18899561
G Cfb complement factor B IMP compared to wild type SHR RGD PMID:28739975 RGD:127285403 NCBI chr20:3,975,271...3,981,138
Ensembl chr20:3,951,474...3,976,505
JBrowse link
G Cfbem1Tja complement factor B, ZFN induced mutant 1, Tja IMP compared to wild type SHR RGD PMID:28739975 RGD:127285403
G Gper1 G protein-coupled estrogen receptor 1 IMP compared to wild type SS rat RGD PMID:30354811 RGD:39939000 NCBI chr12:20,331,073...20,336,527
Ensembl chr12:15,217,442...15,221,889
JBrowse link
G Gper1em1Bj G protein-coupled estrogen receptor 1; CRISPR/Cas 9 induced mutant 1, Bj IMP compared to wild type SS rat RGD PMID:30354811 RGD:39939000
G Rarres2 retinoic acid receptor responder 2 sexual_dimorphism IMP compared to female wild-type RGD PMID:29906243 PMID:29906243 RGD:38596340, RGD:38596340 NCBI chr 4:78,853,450...78,856,652
Ensembl chr 4:77,522,535...77,525,556
JBrowse link
G Rarres2em1Msu retinoic acid receptor responder 2; CRISPR/Cas9 induced mutant 1, Msu sexual_dimorphism IMP compared to female wild-type RGD PMID:29906243 PMID:29906243 RGD:38596340, RGD:38596340
G Ren renin sexual_dimorphism IMP compared to wild type
compared to wild type male
RGD PMID:21242461 PMID:21242461 RGD:7771614, RGD:7771614 NCBI chr13:47,348,312...47,359,539
Ensembl chr13:44,796,091...44,807,489
JBrowse link
G Renem1Mcwi renin; zinc finger nuclease induced mutant 1, Medical College of Wisconsin sexual_dimorphism IMP compared to wild type male RGD PMID:21242461 PMID:21242461 RGD:7771614, RGD:7771614
G test test1 TAS
IDA
fr str628908
fr str61106wastas
RGD PMID:9453331 PMID:9453331 RGD:619652, RGD:619652
decreased systemic vascular resistance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plekha7 pleckstrin homology domain containing A7 induces IMP compared to wild type RGD PMID:25136115 PMID:25136115 RGD:11079199, RGD:11079199 NCBI chr 1:179,798,856...179,982,155
Ensembl chr 1:170,365,135...170,547,775
JBrowse link
G Plekha7em4Mcwi pleckstrin homology domain containing, family A member 7; zinc finger nuclease induced mutant 4, Medical College of Wisconsin induces IMP compared to wild type RGD PMID:25136115 PMID:25136115 RGD:11079199, RGD:11079199
decreased vascular permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Add3 adducin 3 IMP RGD PMID:32029431 RGD:150340736 NCBI chr 1:262,152,722...262,260,504
Ensembl chr 1:252,147,386...252,255,124
JBrowse link
G Mmp2 matrix metallopeptidase 2 ameliorates IMP associated with Experimental Diabetes Mellitus, compared to wild type SS RGD PMID:37643020 RGD:401827835 NCBI chr19:30,327,643...30,355,856
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp2em2Mcwi matrix metallopeptidase 2; zinc finger nuclease induced mutant 2, Medical College of Wisconsin ameliorates IMP associated with Experimental Diabetes Mellitus, compared to wild type SS RGD PMID:37643020 RGD:401827835
decreased vasoconstriction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Add3 adducin 3 induces IMP compared to WT RGD PMID:32029431 RGD:150340736 NCBI chr 1:262,152,722...262,260,504
Ensembl chr 1:252,147,386...252,255,124
JBrowse link
G Add3em1Mcwi adducin 3; ZFN induced mutant1, Mcwi induces IMP compared to wild-type RGD PMID:32029431 RGD:150340736
G Add3em2Mcwi adducin 3; ZFN induced mutant2, Mcwi induces IMP compared to WT RGD PMID:32029431 RGD:150340736
G Dusp5 dual specificity phosphatase 5 IMP compared to FHH.1BN RGD PMID:25397684 RGD:13446412 NCBI chr 1:262,543,774...262,557,201
Ensembl chr 1:252,538,449...252,551,818
JBrowse link
G Dusp5em1Mcwi dual specificity phosphatase 5; ZFN induced mutant1, Mcwi IMP compared to FHH.1BN RGD PMID:25397684 RGD:13446412
G Mc4r melanocortin 4 receptor IMP RGD PMID:24400148 RGD:13825242 NCBI chr18:62,689,798...62,691,685
Ensembl chr18:60,419,832...60,421,719
JBrowse link
G Mc4rm1Hubr melanocortin 4 receptor; ENU induced mutation 1, Hubr IMP RGD PMID:24400148 RGD:13825242
G Slc6a4 solute carrier family 6 member 4 IMP RGD PMID:18263707 RGD:4889513 NCBI chr10:62,322,688...62,357,060
Ensembl chr10:61,826,123...61,858,384
JBrowse link
decreased vasodilation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnk3 potassium two pore domain channel subfamily K member 3 IMP RGD PMID:31347976 RGD:151347452 NCBI chr 6:31,483,129...31,519,061
Ensembl chr 6:25,763,228...25,799,153
JBrowse link
G Kcnk3em1Ang potassium two pore domain channel subfamily K member 3; CRISPR/Cas9 induced mutant1, Ang IMP RGD PMID:31347976 RGD:151347452
G Mir29b1 microRNA 29b-1 IMP RGD PMID:29374012 RGD:13702880 NCBI chr 4:60,618,334...60,618,414
Ensembl chr 4:59,650,986...59,651,067
JBrowse link
G Mir29b1em1Mcwi microRNA 29b-1; TALEN induced mutant 1, Medical College of Wisconsin IMP RGD PMID:29374012 RGD:13702880
G Nfe2l2 NFE2 like bZIP transcription factor 2 IMP compared to SD RGD PMID:26637559 RGD:11344212 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfe2l2em1Mcwi nuclear factor, erythroid 2-like 2; TALEN induced mutant 1, Medical College of Wisconsin IMP compared to SD RGD PMID:26637559 RGD:11344212
G Sod3 superoxide dismutase 3 IMP compared to SS/JrHsdMcwi;DNA:missense mutation:cds:p.E124D RGD PMID:24322611 RGD:38548929 NCBI chr14:62,822,865...62,828,602
Ensembl chr14:58,609,958...58,615,990
JBrowse link
G Sod3m1Mcwi superoxide dismutase 3; mutation 1, Medical College of Wisconsin IMP compared to SS/JrHsdMcwi;DNA:missense mutation:cds:p.E124D RGD PMID:24322611 RGD:38548929
heart left ventricle hypertrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ednra endothelin receptor type A IDA RGD PMID:16157796 RGD:1581830 NCBI chr19:47,137,360...47,207,961
Ensembl chr19:30,233,571...30,297,049
JBrowse link
G Egfr epidermal growth factor receptor IDA RGD PMID:12624003 RGD:1580955 NCBI chr14:95,378,626...95,551,358
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Lepr leptin receptor treatment IAGP RGD PMID:33568522 RGD:401965412 NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
G Myh7b myosin heavy chain 7B IMP RGD PMID:32207065 RGD:126925946 NCBI chr 3:164,537,211...164,582,441
Ensembl chr 3:144,098,190...144,122,084
JBrowse link
G Myh7bem1Blar myosin heavy chain 7B; CRISPR/Cas9 induced mutant 1, Blar IMP RGD PMID:32207065 RGD:126925946
G Sod3 superoxide dismutase 3 IMP compared to SS/JrHsdMcwi RGD PMID:31972339 RGD:150573712 NCBI chr14:62,822,865...62,828,602
Ensembl chr14:58,609,958...58,615,990
JBrowse link
G Sod3m1Mcwi superoxide dismutase 3; mutation 1, Medical College of Wisconsin IMP compared to SS/JrHsdMcwi RGD PMID:31972339 RGD:150573712
hemarthrosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F8 coagulation factor VIII treatment IMP RGD PMID:27060449 PMID:31899798 RGD:150520059, RGD:150520060 NCBI chr18:155,237...187,186
Ensembl chr18:140,955...171,857
JBrowse link
G F8em1Sage coagulation factor VIII, procoagulant component; zinc finger nuclease induced mutant1, Sage treatment IMP RGD PMID:31899798 PMID:27060449 RGD:150520060, RGD:150520059
G F8em1Mcwi coagulation factor VIII, procoagulant component; CRISPR/Cas9 induced mutant1, Mcwi treatment IMP RGD PMID:31899798 RGD:150520060
hemorrhage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F8 coagulation factor VIII IMP RGD PMID:24931420 RGD:11530071 NCBI chr18:155,237...187,186
Ensembl chr18:140,955...171,857
JBrowse link
G F8em1Sage coagulation factor VIII, procoagulant component; zinc finger nuclease induced mutant1, Sage IMP RGD PMID:24931420 RGD:11530071
hypertension term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lepr leptin receptor IMP
IAGP
DNA:mutations:cds: : (rat) RGD PMID:27465994 PMID:30278832 RGD:12911217, RGD:401960095 NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
G Nppb natriuretic peptide B IMP RGD PMID:26063669 RGD:12910116 NCBI chr 5:163,699,955...163,701,314
Ensembl chr 5:158,416,866...158,418,168
JBrowse link
G Nppbem2Mcwi natriuretic peptide B; zinc finger nuclease induced mutant 2, Medical College of Wisconsin IMP RGD PMID:26063669 RGD:12910116
increased aorta wall thickness term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddah1 dimethylarginine dimethylaminohydrolase 1 exacerbates
induces
IMP compared to wild type RGD PMID:31402164 PMID:31402164 RGD:151347602, RGD:151347602 NCBI chr 2:237,327,812...237,460,624
Ensembl chr 2:234,667,491...234,799,339
JBrowse link
G Ddah1em1Ywxu dimethylarginine dimethylaminohydrolase 1; CRISPR/Cas9 induced mutant 1, Ywxu induces
exacerbates
IMP compared to wild type RGD PMID:31402164 PMID:31402164 RGD:151347602, RGD:151347602
increased cardiac muscle calcium level term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myh7b myosin heavy chain 7B IMP RGD PMID:32207065 RGD:126925946 NCBI chr 3:164,537,211...164,582,441
Ensembl chr 3:144,098,190...144,122,084
JBrowse link
G Myh7bem1Blar myosin heavy chain 7B; CRISPR/Cas9 induced mutant 1, Blar IMP RGD PMID:32207065 RGD:126925946
increased cardiac muscle contractility term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1rl2 interleukin 1 receptor-like 2 IMP compared to Wild Type in cardiopulmonary bypass model RGD PMID:32048631 RGD:126925167 NCBI chr 9:42,591,658...42,639,351
Ensembl chr 9:42,591,934...42,636,667
JBrowse link
G Il1rl2tm1(Myh6-cre)Mhzh interleukin 1 receptor-like 2; tm1 (Myh6-cre), Mhzh IMP compared to Wild Type in cardiopulmonary bypass model RGD PMID:32048631 RGD:126925167
increased cardiac output term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plekha7 pleckstrin homology domain containing A7 IMP compared to wild type RGD PMID:25136115 PMID:25136115 RGD:11079199, RGD:11079199 NCBI chr 1:179,798,856...179,982,155
Ensembl chr 1:170,365,135...170,547,775
JBrowse link
G Plekha7em4Mcwi pleckstrin homology domain containing, family A member 7; zinc finger nuclease induced mutant 4, Medical College of Wisconsin IMP compared to wild type RGD PMID:25136115 PMID:25136115 RGD:11079199, RGD:11079199
increased cardiac stroke volume term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plekha7 pleckstrin homology domain containing A7 induces IMP compared to wild type RGD PMID:25136115 PMID:25136115 RGD:11079199, RGD:11079199 NCBI chr 1:179,798,856...179,982,155
Ensembl chr 1:170,365,135...170,547,775
JBrowse link
G Plekha7em4Mcwi pleckstrin homology domain containing, family A member 7; zinc finger nuclease induced mutant 4, Medical College of Wisconsin induces IMP compared to wild type RGD PMID:25136115 PMID:25136115 RGD:11079199, RGD:11079199
increased heart left ventricle anterior wall thickness term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lepr leptin receptor IAGP DNA:mutations:cds: : (rat) RGD PMID:32710530 RGD:401960103 NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
increased heart left ventricle posterior wall thickness term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myh7b myosin heavy chain 7B IMP RGD PMID:32207065 RGD:126925946 NCBI chr 3:164,537,211...164,582,441
Ensembl chr 3:144,098,190...144,122,084
JBrowse link
G Myh7bem1Blar myosin heavy chain 7B; CRISPR/Cas9 induced mutant 1, Blar IMP RGD PMID:32207065 RGD:126925946
increased heart left ventricle weight term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lepr leptin receptor IAGP DNA:mutations:cds: : (rat) RGD PMID:32710530 RGD:401960103 NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
increased heart rate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmal1 basic helix-loop-helix ARNT like 1 sexual_dimorphism IMP in female RGD PMID:32306766 RGD:155598602 NCBI chr 1:176,766,222...176,864,741
Ensembl chr 1:167,331,633...167,430,231
JBrowse link
G Bmal1em1Mcwi basic helix-loop-helix ARNT like 1;CRISPR/Cas9 induced mutant 1,Mcwi sexual_dimorphism IMP in female RGD PMID:32306766 RGD:155598602
G Glp1r glucagon-like peptide 1 receptor IDA RGD PMID:12093887 RGD:625448 NCBI chr20:8,973,393...9,011,622
Ensembl chr20:8,972,004...9,010,241
JBrowse link
G Kcnk3 potassium two pore domain channel subfamily K member 3 IMP RGD PMID:31347976 RGD:151347452 NCBI chr 6:31,483,129...31,519,061
Ensembl chr 6:25,763,228...25,799,153
JBrowse link
G Kcnk3em1Ang potassium two pore domain channel subfamily K member 3; CRISPR/Cas9 induced mutant1, Ang IMP RGD PMID:31347976 RGD:151347452
G Ren renin IMP compared to wild type RGD PMID:21242461 RGD:7771614 NCBI chr13:47,348,312...47,359,539
Ensembl chr13:44,796,091...44,807,489
JBrowse link
G Renem1Mcwi renin; zinc finger nuclease induced mutant 1, Medical College of Wisconsin IMP compared to wild type RGD PMID:21242461 RGD:7771614
increased heart right ventricle weight term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddah1 dimethylarginine dimethylaminohydrolase 1 exacerbates IMP RGD PMID:31402164 RGD:151347602 NCBI chr 2:237,327,812...237,460,624
Ensembl chr 2:234,667,491...234,799,339
JBrowse link
G Ddah1em1Ywxu dimethylarginine dimethylaminohydrolase 1; CRISPR/Cas9 induced mutant 1, Ywxu exacerbates IMP RGD PMID:31402164 RGD:151347602
increased heart ventricle muscle contractility term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr2f2 nuclear receptor subfamily 2, group F, member 2 IMP compared to SS/JrHsdMcw RGD PMID:25687237 RGD:10401852 NCBI chr 1:133,419,161...133,434,290
Ensembl chr 1:124,009,181...124,022,031
JBrowse link
G Nr2f2em1Mcwi nuclear receptor subfamily 2, group F, member 2; zinc finger nuclease induced mutant 1, Medical College of Wisconsin IMP compared to SS/JrHsdMcw RGD PMID:25687237 RGD:10401852
increased heart weight term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dmd dystrophin IMP RGD PMID:25005781 RGD:11040981 NCBI chr  X:51,070,098...53,437,845
Ensembl chr  X:47,272,331...49,504,207
JBrowse link
G Dmdem1Kykn dystrophin; CRISPR/Cas9 system induced mutant 1, Keitaro Yamanouchi IMP RGD PMID:25005781 RGD:11040981
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 IMP compared to wild type RGD PMID:26077568 RGD:13800514 NCBI chr19:50,307,569...50,312,812
Ensembl chr19:33,397,656...33,402,899
JBrowse link
G Hsd11b2em1Jmul hydroxysteroid 11-beta dehydrogenase 2; ZFN induced mutant1, Jmul IMP compared to wild type RGD PMID:26077568 RGD:13800514
G Lamp2 lysosomal-associated membrane protein 2 IMP in hemizygote mutant male (LAMP2y/-) RGD PMID:29720683 RGD:13703117 NCBI chr  X:122,038,734...122,087,745
Ensembl chr  X:117,057,606...117,260,522
JBrowse link
G Lamp2em1 lysosomal-associated membrane protein 2; TALEN induced mutant1 IMP in hemizygote mutant male (LAMP2y/-) RGD PMID:29720683 RGD:13703117
G Mc4r melanocortin 4 receptor IMP RGD PMID:24400148 RGD:13825242 NCBI chr18:62,689,798...62,691,685
Ensembl chr18:60,419,832...60,421,719
JBrowse link
G Mc4rm1Hubr melanocortin 4 receptor; ENU induced mutation 1, Hubr IMP RGD PMID:24400148 RGD:13825242
G Mthfr methylenetetrahydrofolate reductase IMP as compared to the wild-type RGD PMID:24006081 RGD:8662415 NCBI chr 5:163,748,346...163,768,141
Ensembl chr 5:158,465,296...158,483,797
JBrowse link
G Nppa natriuretic peptide A IMP as compared to the wild-type RGD PMID:24006081 RGD:8662415 NCBI chr 5:163,712,184...163,713,493
Ensembl chr 5:158,429,042...158,430,351
JBrowse link
increased left ventricle diastolic pressure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lepr leptin receptor IAGP DNA:mutations:cds: : (rat) RGD PMID:32710530 RGD:401960103 NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
increased left ventricle systolic pressure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1rl2 interleukin 1 receptor-like 2 IMP compared to Wild Type in cardiopulmonary bypass model RGD PMID:32048631 RGD:126925167 NCBI chr 9:42,591,658...42,639,351
Ensembl chr 9:42,591,934...42,636,667
JBrowse link
G Il1rl2tm1(Myh6-cre)Mhzh interleukin 1 receptor-like 2; tm1 (Myh6-cre), Mhzh IMP compared to Wild Type in cardiopulmonary bypass model RGD PMID:32048631 RGD:126925167
increased mean systemic arterial blood pressure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alms1 ALMS1, centrosome and basal body associated protein exacerbates IMP compared to wild type RGD PMID:30385718 RGD:151361229 NCBI chr 4:119,683,085...119,783,471
Ensembl chr 4:118,125,607...118,226,005
JBrowse link
G Alms1em1Mcwi Alstrom syndrome 1 homolog (human); zinc finger nuclease induced mutant 1, Medical College of Wisconsin exacerbates IMP compared to wild type RGD PMID:30385718 RGD:151361229
G Lepr leptin receptor IAGP DNA:mutations:cds: : (rat) RGD PMID:32710530 RGD:401960103 NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
G Nppa natriuretic peptide A IMP as compared to the wild-type RGD PMID:24006081 RGD:8662415 NCBI chr 5:163,712,184...163,713,493
Ensembl chr 5:158,429,042...158,430,351
JBrowse link
G Rag1 recombination activating 1 IMP on 4% NaCl diet RGD PMID:23364523 RGD:7207429 NCBI chr 3:108,372,087...108,383,184
Ensembl chr 3:87,917,004...87,928,291
JBrowse link
G Rag1em1Mcwi recombination activating gene 1; zinc finger nuclease induced mutant 1, Medical College of Wisconsin IMP on 4% NaCl diet RGD PMID:23364523 RGD:7207429
G Rag1em2Mcwi recombination activating gene 1; zinc finger nuclease induced mutant 2, Medical College of Wisconsin IMP on 4% NaCl diet RGD PMID:23364523 RGD:7207429
G Rarres2 retinoic acid receptor responder 2 sexual_dimorphism IMP compared to male wild-type RGD PMID:29906243 PMID:29906243 RGD:38596340, RGD:38596340 NCBI chr 4:78,853,450...78,856,652
Ensembl chr 4:77,522,535...77,525,556
JBrowse link
G Rarres2em1Msu retinoic acid receptor responder 2; CRISPR/Cas9 induced mutant 1, Msu sexual_dimorphism IMP compared to male wild-type RGD PMID:29906243 PMID:29906243 RGD:38596340, RGD:38596340
G Sod3 superoxide dismutase 3 onset IMP compared to SS/JrHsdMcwi RGD PMID:31972339 RGD:150573712 NCBI chr14:62,822,865...62,828,602
Ensembl chr14:58,609,958...58,615,990
JBrowse link
G Sod3m1Mcwi superoxide dismutase 3; mutation 1, Medical College of Wisconsin onset IMP compared to SS/JrHsdMcwi RGD PMID:31972339 RGD:150573712
G Tmem67 transmembrane protein 67 IAGP RGD PMID:11095650 RGD:1300514 NCBI chr 5:30,333,793...30,386,702
Ensembl chr 5:25,536,458...25,589,334
JBrowse link
G Tmem67wpk transmembrane protein 67; wpk mutant IAGP RGD PMID:11095650 RGD:1300514
increased myocardial fiber size term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myh7b myosin heavy chain 7B IMP RGD PMID:32207065 RGD:126925946 NCBI chr 3:164,537,211...164,582,441
Ensembl chr 3:144,098,190...144,122,084
JBrowse link
G Myh7bem1Blar myosin heavy chain 7B; CRISPR/Cas9 induced mutant 1, Blar IMP RGD PMID:32207065 RGD:126925946
increased myocardial infarct size term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ubd ubiquitin D IMP associated with induced myocardial infarction RGD PMID:29438664 RGD:126925221 NCBI chr20:1,390,734...1,392,685
Ensembl chr20:1,385,864...1,408,639
Ensembl chr20:1,385,864...1,408,639
JBrowse link
G Ubdem1 ubiquitin D; CRISPR/Cas9 induced mutant1 IMP associated with induced myocardial infarction RGD PMID:29438664 RGD:126925221
increased pulmonary vascular resistance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnk3 potassium two pore domain channel subfamily K member 3 IMP RGD PMID:31347976 RGD:151347452 NCBI chr 6:31,483,129...31,519,061
Ensembl chr 6:25,763,228...25,799,153
JBrowse link
G Kcnk3em1Ang potassium two pore domain channel subfamily K member 3; CRISPR/Cas9 induced mutant1, Ang IMP RGD PMID:31347976 RGD:151347452
increased pulse pressure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rarres2 retinoic acid receptor responder 2 sexual_dimorphism IMP compared to male wild-type RGD PMID:29906243 PMID:29906243 RGD:38596340, RGD:38596340 NCBI chr 4:78,853,450...78,856,652
Ensembl chr 4:77,522,535...77,525,556
JBrowse link
G Rarres2em1Msu retinoic acid receptor responder 2; CRISPR/Cas9 induced mutant 1, Msu sexual_dimorphism IMP compared to male wild-type RGD PMID:29906243 PMID:29906243 RGD:38596340, RGD:38596340
increased renal vascular resistance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lepr leptin receptor IAGP DNA:mutations::cds: : (rat) RGD PMID:10901178 RGD:401965414 NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
increased right ventricle systolic pressure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor ameliorates IMP compared to wild type littermates RGD PMID:33836606 RGD:401940192 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Ahrem1Iexas aryl hydrocarbon receptor; CRISPR/Cas9 induced mutant1, Iexas ameliorates IMP compared to wild type littermates RGD PMID:33836606 RGD:401940192
G Ddah1 dimethylarginine dimethylaminohydrolase 1 induces IMP compared to wild type RGD PMID:31402164 RGD:151347602 NCBI chr 2:237,327,812...237,460,624
Ensembl chr 2:234,667,491...234,799,339
JBrowse link
G Ddah1em1Ywxu dimethylarginine dimethylaminohydrolase 1; CRISPR/Cas9 induced mutant 1, Ywxu induces IMP compared to wild type RGD PMID:31402164 RGD:151347602
G Kcnk3 potassium two pore domain channel subfamily K member 3 onset IMP RGD PMID:31347976 RGD:151347452 NCBI chr 6:31,483,129...31,519,061
Ensembl chr 6:25,763,228...25,799,153
JBrowse link
G Kcnk3em1Ang potassium two pore domain channel subfamily K member 3; CRISPR/Cas9 induced mutant1, Ang onset IMP RGD PMID:31347976 RGD:151347452
increased systemic arterial blood pressure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E IMP RGD PMID:29166645 RGD:150520219 NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Apoeem1Ejt apolipoprotein E; TALEN induced mutant 1, Ejt IMP RGD PMID:29166645 RGD:150520219
G Apoeem1Sage apolipoprotein E; endonuclease induced mutant 1, Sigma Advanced Genetic Engineering Labs IMP RGD PMID:29166645 RGD:150520219
G Ddx52 DExD-box helicase 52 IAGP DNA:polymorphism RGD PMID:17218081 RGD:1599269 NCBI chr10:69,322,062...69,344,856
Ensembl chr10:68,824,645...68,848,266
JBrowse link
G Ednrb endothelin receptor type B IDA RGD PMID:16179487 RGD:1581856 NCBI chr15:87,055,490...87,086,765
Ensembl chr15:80,643,043...80,672,115
JBrowse link
G Glp1r glucagon-like peptide 1 receptor IDA RGD PMID:12093887 RGD:625448 NCBI chr20:8,973,393...9,011,622
Ensembl chr20:8,972,004...9,010,241
JBrowse link
G Kcnmb1 potassium calcium-activated channel subfamily M regulatory beta subunit 1 IDA RGD PMID:14551242 RGD:1298970 NCBI chr10:19,062,014...19,119,005
Ensembl chr10:18,557,904...18,565,798
JBrowse link
G Npr1 natriuretic peptide receptor 1 IAGP RGD PMID:7629399 RGD:1357231 NCBI chr 2:178,231,766...178,247,591
Ensembl chr 2:175,934,181...175,949,505
JBrowse link
G Ren renin IAGP RGD PMID:8567976 RGD:61046 NCBI chr13:47,348,312...47,359,539
Ensembl chr13:44,796,091...44,807,489
JBrowse link
G Tnf tumor necrosis factor IAGP RGD PMID:9590569 RGD:1357163 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629
JBrowse link
increased systemic arterial diastolic blood pressure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nppa natriuretic peptide A IMP as compared to the wild-type RGD PMID:24006081 RGD:8662415 NCBI chr 5:163,712,184...163,713,493
Ensembl chr 5:158,429,042...158,430,351
JBrowse link
G Npr1 natriuretic peptide receptor 1 IAGP RGD PMID:12511524 RGD:628585 NCBI chr 2:178,231,766...178,247,591
Ensembl chr 2:175,934,181...175,949,505
JBrowse link
G Rarres2 retinoic acid receptor responder 2 sexual_dimorphism IMP RGD PMID:29906243 RGD:38596340 NCBI chr 4:78,853,450...78,856,652
Ensembl chr 4:77,522,535...77,525,556
JBrowse link
G Rarres2em1Msu retinoic acid receptor responder 2; CRISPR/Cas9 induced mutant 1, Msu sexual_dimorphism IMP RGD PMID:29906243 RGD:38596340
G Sod3 superoxide dismutase 3 onset IMP compared to SS/JrHsdMcwi RGD PMID:31972339 RGD:150573712 NCBI chr14:62,822,865...62,828,602
Ensembl chr14:58,609,958...58,615,990
JBrowse link
G Sod3m1Mcwi superoxide dismutase 3; mutation 1, Medical College of Wisconsin onset IMP compared to SS/JrHsdMcwi RGD PMID:31972339 RGD:150573712
increased systemic arterial systolic blood pressure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Add1 adducin 1 IAGP RGD PMID:15474463 RGD:1302895 NCBI chr14:80,333,242...80,401,641
Ensembl chr14:76,108,654...76,167,182
JBrowse link
G Adora2b adenosine A2B receptor IMP RGD PMID:26385692 RGD:11533328 NCBI chr10:47,439,712...47,456,092
Ensembl chr10:46,940,384...46,956,772
JBrowse link
G Adora2bem2Mcwi adenosine A2B receptor; zinc finger nuclease induced mutant 2, Medical College of Wisconsin IMP RGD PMID:26385692 RGD:11533328
G Alms1 ALMS1, centrosome and basal body associated protein exacerbates IMP compared to wild type RGD PMID:30385718 RGD:151361229 NCBI chr 4:119,683,085...119,783,471
Ensembl chr 4:118,125,607...118,226,005
JBrowse link
G Alms1em1Mcwi Alstrom syndrome 1 homolog (human); zinc finger nuclease induced mutant 1, Medical College of Wisconsin exacerbates IMP compared to wild type RGD PMID:30385718 RGD:151361229
G Cyp11b1 cytochrome P450, family 11, subfamily b, polypeptide 1 IAGP RGD PMID:7981756 RGD:69709 NCBI chr 7:108,653,385...108,660,062
Ensembl chr 7:106,718,274...106,779,278
JBrowse link
G Ednra endothelin receptor type A IDA RGD PMID:16157796 RGD:1581830 NCBI chr19:47,137,360...47,207,961
Ensembl chr19:30,233,571...30,297,049
JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 IAGP DNA:duplication RGD PMID:20231529 RGD:11251783 NCBI chr19:69,765,276...69,804,681
Ensembl chr19:52,869,486...52,907,777
JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 IAGP DNA:deletion:exon (rat) RGD PMID:16368876 RGD:1581602 NCBI chr 1:207,721,134...208,054,073
Ensembl chr 1:198,291,766...198,624,669
JBrowse link
G Kcnq1dfk potassium voltage-gated channel subfamily Q member 1;deafness Kyoto IAGP RGD PMID:16368876 RGD:1581602
G Lepr leptin receptor treatment
onset
IAGP
IMP
compared to treated
compared to SS/JrHsdMcwi
RGD PMID:23154293 PMID:33568522 PMID:27465994 RGD:13432147, RGD:401965412, RGD:12911217 NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
G Leprem2Mcwi leptin receptor; zinc finger nuclease induced mutant 2, Medical College of Wisconsin onset IMP compared to SS/JrHsdMcwi RGD PMID:27465994 RGD:12911217
G Leprfa leptin receptor; fa mutant IAGP RGD PMID:23154293 RGD:13432147
G Nppa natriuretic peptide A IMP as compared to the wild-type RGD PMID:24006081 RGD:8662415 NCBI chr 5:163,712,184...163,713,493
Ensembl chr 5:158,429,042...158,430,351
JBrowse link
G Plod1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 IMP as compared to the wild-type RGD PMID:24006081 RGD:8662415 NCBI chr 5:163,623,847...163,650,737
Ensembl chr 5:158,340,490...158,367,620
JBrowse link
G Rarres2 retinoic acid receptor responder 2 sexual_dimorphism IMP compared to male wild-type RGD PMID:29906243 PMID:29906243 RGD:38596340, RGD:38596340 NCBI chr 4:78,853,450...78,856,652
Ensembl chr 4:77,522,535...77,525,556
JBrowse link
G Rarres2em1Msu retinoic acid receptor responder 2; CRISPR/Cas9 induced mutant 1, Msu sexual_dimorphism IMP compared to male wild-type RGD PMID:29906243 PMID:29906243 RGD:38596340, RGD:38596340
G Sod3 superoxide dismutase 3 onset IMP compared to SS/JrHsdMcwi RGD PMID:31972339 RGD:150573712 NCBI chr14:62,822,865...62,828,602
Ensembl chr14:58,609,958...58,615,990
JBrowse link
G Sod3m1Mcwi superoxide dismutase 3; mutation 1, Medical College of Wisconsin onset IMP compared to SS/JrHsdMcwi RGD PMID:31972339 RGD:150573712
increased systemic vascular resistance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2b adenosine A2B receptor IMP RGD PMID:26385692 RGD:11533328 NCBI chr10:47,439,712...47,456,092
Ensembl chr10:46,940,384...46,956,772
JBrowse link
G Adora2bem2Mcwi adenosine A2B receptor; zinc finger nuclease induced mutant 2, Medical College of Wisconsin IMP RGD PMID:26385692 RGD:11533328
G Mc4r melanocortin 4 receptor IMP RGD PMID:24400148 RGD:13825242 NCBI chr18:62,689,798...62,691,685
Ensembl chr18:60,419,832...60,421,719
JBrowse link
G Mc4rm1Hubr melanocortin 4 receptor; ENU induced mutation 1, Hubr IMP RGD PMID:24400148 RGD:13825242
increased vascular permeability term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tmem67 transmembrane protein 67 IAGP RGD PMID:30705305 RGD:14995942 NCBI chr 5:30,333,793...30,386,702
Ensembl chr 5:25,536,458...25,589,334
JBrowse link
G Tmem67wpk transmembrane protein 67; wpk mutant IAGP RGD PMID:30705305 RGD:14995942
increased vasoconstriction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr7 5-hydroxytryptamine receptor 7 IMP RGD PMID:31125292 RGD:14696718 NCBI chr 1:233,636,442...233,761,063
Ensembl chr 1:233,636,452...233,760,626
JBrowse link
G Htr7em1Msu 5-hydroxytryptamine receptor 7; CRISPR/Cas9 induced mutant 1, Msu IMP RGD PMID:31125292 RGD:14696718
G Mc4r melanocortin 4 receptor IMP RGD PMID:24400148 RGD:13825242 NCBI chr18:62,689,798...62,691,685
Ensembl chr18:60,419,832...60,421,719
JBrowse link
G Mc4rm1Hubr melanocortin 4 receptor; ENU induced mutation 1, Hubr IMP RGD PMID:24400148 RGD:13825242
G Rarres2 retinoic acid receptor responder 2 sexual_dimorphism IMP
IAGP
compared to female knockout
compared to wild-type
RGD PMID:29906243 PMID:29906243 PMID:29906243 RGD:38596340, RGD:38596340, RGD:38596340 NCBI chr 4:78,853,450...78,856,652
Ensembl chr 4:77,522,535...77,525,556
JBrowse link
G Rarres2em1Msu retinoic acid receptor responder 2; CRISPR/Cas9 induced mutant 1, Msu sexual_dimorphism IMP
IAGP
compared to female knockout
compared to wild-type
RGD PMID:29906243 PMID:29906243 PMID:29906243 RGD:38596340, RGD:38596340, RGD:38596340
G Shc1 SHC adaptor protein 1 IMP RGD PMID:27270176 RGD:12792230 NCBI chr 2:177,135,649...177,147,257
Ensembl chr 2:174,837,930...174,849,536
JBrowse link
G Shc1em1Mcwi SHC adaptor protein 1; ZFN induced mutant 1, Medical College of Wisconsin IMP RGD PMID:27270176 RGD:12792230
G Shc1em4Mcwi SHC adaptor protein 1; ZFN induced mutant 4, Medical College of Wisconsin IMP RGD PMID:27270176 RGD:12792230
G Sod3 superoxide dismutase 3 IMP XCO:0000145;DNA:missense mutation:cds:p.E124D RGD PMID:24322611 RGD:38548929 NCBI chr14:62,822,865...62,828,602
Ensembl chr14:58,609,958...58,615,990
JBrowse link
G Sod3m1Mcwi superoxide dismutase 3; mutation 1, Medical College of Wisconsin IMP XCO:0000145 RGD PMID:24322611 RGD:38548929
increased vasodilation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gper1 G protein-coupled estrogen receptor 1 IMP compared to wild type SS rat RGD PMID:30354811 RGD:39939000 NCBI chr12:20,331,073...20,336,527
Ensembl chr12:15,217,442...15,221,889
JBrowse link
G Gper1em1Bj G protein-coupled estrogen receptor 1; CRISPR/Cas 9 induced mutant 1, Bj IMP compared to wild type SS rat RGD PMID:30354811 RGD:39939000
G Hmox1 heme oxygenase 1 IDA RGD PMID:15057912 RGD:1580452 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Plekha7 pleckstrin homology domain containing A7 IMP compared to wild type RGD PMID:25136115 RGD:11079199 NCBI chr 1:179,798,856...179,982,155
Ensembl chr 1:170,365,135...170,547,775
JBrowse link
G Plekha7em4Mcwi pleckstrin homology domain containing, family A member 7; zinc finger nuclease induced mutant 4, Medical College of Wisconsin IMP compared to wild type RGD PMID:25136115 RGD:11079199
G Sod3 superoxide dismutase 3 IMP compared to SS/JrHsdMcwi;DNA:missense mutation:CDS:p.E124D RGD PMID:24322611 RGD:38548929 NCBI chr14:62,822,865...62,828,602
Ensembl chr14:58,609,958...58,615,990
JBrowse link
G Sod3m1Mcwi superoxide dismutase 3; mutation 1, Medical College of Wisconsin IMP compared to SS/JrHsdMcwi;DNA:missense mutation:CDS:p.E124D RGD PMID:24322611 RGD:38548929
intracranial hemorrhage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccdc39 coiled-coil domain 39 molecular ruler complex subunit IMP RGD PMID:31771992 RGD:150521527 NCBI chr 2:118,593,881...118,631,584
Ensembl chr 2:116,665,261...116,703,350
JBrowse link
G Ccdc39em1Jgn coiled-coil domain containing 39; CRISPR/Cas9 induced mutant 1, Jgn IMP RGD PMID:31771992 RGD:150521527
G Ccdc85c coiled-coil domain containing 85C IMP RGD PMID:31341137 RGD:150520163 NCBI chr 6:132,877,851...132,948,744
Ensembl chr 6:127,113,442...127,184,371
JBrowse link
G Ccdc85cem1Kyo coiled-coil domain containing 85C; TALEN induced mutant1,Kyo IMP RGD PMID:31341137 RGD:150520163
myocardium steatosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E IMP RGD PMID:28808185 RGD:13703132 NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
pathological neovascularization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epha2 Eph receptor A2 IDA RGD PMID:16359662 RGD:1580975 NCBI chr 5:158,888,629...158,917,100
Ensembl chr 5:153,605,644...153,634,117
JBrowse link
G Kdr kinase insert domain receptor IDA inhibition reduces portal-systemic collateral vessel formation RGD PMID:14988842 RGD:2292014 NCBI chr14:32,572,031...32,615,204
Ensembl chr14:32,217,871...32,261,018
JBrowse link
prolonged QT interval term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 IAGP DNA:deletion:exon (rat) RGD PMID:16368876 RGD:1581602 NCBI chr 1:207,721,134...208,054,073
Ensembl chr 1:198,291,766...198,624,669
JBrowse link
G Kcnq1dfk potassium voltage-gated channel subfamily Q member 1;deafness Kyoto IAGP RGD PMID:16368876 RGD:1581602
G Nppb natriuretic peptide B IMP RGD PMID:26063669 RGD:12910116 NCBI chr 5:163,699,955...163,701,314
Ensembl chr 5:158,416,866...158,418,168
JBrowse link
G Nppbem2Mcwi natriuretic peptide B; zinc finger nuclease induced mutant 2, Medical College of Wisconsin IMP RGD PMID:26063669 RGD:12910116
pulmonary hypertension term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor ameliorates IMP compared to wild type littermates RGD PMID:33836606 RGD:401940192 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Ahrem1Iexas aryl hydrocarbon receptor; CRISPR/Cas9 induced mutant1, Iexas ameliorates IMP compared to wild type littermates RGD PMID:33836606 RGD:401940192
pulmonary vascular congestion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lepr leptin receptor treatment IAGP RGD PMID:33568522 RGD:401965412 NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
rectal hemorrhage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway sexual_dimorphism IMP compared to females RGD PMID:17360473 RGD:1601201 NCBI chr18:26,138,382...26,196,021
Ensembl chr18:25,864,222...25,922,696
JBrowse link
G ApcPirc APC, WNT signaling pathway regulator; polyposis in the rat colon sexual_dimorphism IMP compared to females RGD PMID:17360473 RGD:1601201
salt-sensitive hypertension term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alms1 ALMS1, centrosome and basal body associated protein exacerbates IMP compared to wild type RGD PMID:30385718 RGD:151361229 NCBI chr 4:119,683,085...119,783,471
Ensembl chr 4:118,125,607...118,226,005
JBrowse link
G Alms1em1Mcwi Alstrom syndrome 1 homolog (human); zinc finger nuclease induced mutant 1, Medical College of Wisconsin exacerbates IMP compared to wild type RGD PMID:30385718 RGD:151361229
G Astn1 astrotactin 1 IMP RGD PMID:24714719 RGD:12792227 NCBI chr13:73,070,754...73,388,902
Ensembl chr13:70,537,703...70,855,440
JBrowse link
G Brinp2 BMP/retinoic acid inducible neural specific 2 IMP RGD PMID:24714719 RGD:12792227 NCBI chr13:72,964,498...73,065,312
Ensembl chr13:70,431,010...70,531,810
JBrowse link
G Btg2 BTG anti-proliferation factor 2 IAGP RGD PMID:23817491 RGD:12802368 NCBI chr13:48,083,931...48,087,690
Ensembl chr13:45,531,925...45,535,628
JBrowse link
G Cd247 Cd247 molecule severity IMP RGD PMID:24343121 RGD:13442481 NCBI chr13:80,576,264...80,651,422
Ensembl chr13:78,043,307...78,122,263
JBrowse link
G Cd247em1Mcwi Cd247 molecule; zinc finger nuclease induced mutant 1, Medical College of Wisconsin severity IMP RGD PMID:24343121 RGD:13442481
G Chi3l1 chitinase 3 like 1 IAGP RGD PMID:23460292 RGD:12802369 NCBI chr13:48,193,839...48,201,822
Ensembl chr13:45,641,802...45,649,787
JBrowse link
G Chit1 chitinase 1 IAGP RGD PMID:23460292 RGD:12802369 NCBI chr13:48,117,886...48,165,645
Ensembl chr13:45,593,845...45,613,592
JBrowse link
G Cop1 COP1, E3 ubiquitin ligase IMP RGD PMID:24714719 RGD:12792227 NCBI chr13:73,954,058...74,095,283
Ensembl chr13:71,429,961...71,538,890
JBrowse link
G Etnk2 ethanolamine kinase 2 IAGP RGD PMID:23460292 RGD:12802369 NCBI chr13:47,362,964...47,381,100
Ensembl chr13:44,811,015...44,829,037
JBrowse link
G Fmod fibromodulin IAGP RGD PMID:23817491 RGD:12802368 NCBI chr13:48,045,567...48,056,184
Ensembl chr13:45,493,517...45,504,133
JBrowse link
G Gpr37l1 G protein-coupled receptor 37-like 1 IAGP RGD PMID:23460292 RGD:12802369 NCBI chr13:49,150,355...49,157,204
Ensembl chr13:46,598,578...46,605,421
JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 IMP RGD PMID:26077568 RGD:13800514 NCBI chr19:50,307,569...50,312,812
Ensembl chr19:33,397,656...33,402,899
JBrowse link
G Hsd11b2em1Jmul hydroxysteroid 11-beta dehydrogenase 2; ZFN induced mutant1, Jmul IMP RGD PMID:26077568 RGD:13800514
G Ipo9 importin 9 IAGP RGD PMID:23460292 RGD:12802369 NCBI chr13:49,362,244...49,414,477
Ensembl chr13:46,813,171...46,862,673
JBrowse link
G Kcnj1 potassium inwardly-rectifying channel, subfamily J, member 1 IMP RGD PMID:23753405 RGD:13782272 NCBI chr 8:39,014,822...39,066,716
Ensembl chr 8:30,753,617...30,813,796
JBrowse link
G Kcnj1em1Kasu potassium voltage-gated channel subfamily J member 1; ZFN induced mutant 1,Kasu IMP RGD PMID:23753405 RGD:13782272
G Lgr6 leucine-rich repeat-containing G protein-coupled receptor 6 IAGP RGD PMID:23460292 RGD:12802369 NCBI chr13:48,976,193...49,095,870
Ensembl chr13:46,424,383...46,543,945
JBrowse link
G Mgat5 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase IAGP RGD PMID:21257920 RGD:12798539 NCBI chr13:41,228,327...41,516,462
Ensembl chr13:38,676,119...38,959,513
JBrowse link
G Mybph myosin binding protein H IAGP RGD PMID:23460292 RGD:12802369 NCBI chr13:48,205,162...48,212,928
Ensembl chr13:45,653,234...45,660,893
JBrowse link
G Ncf2 neutrophil cytosolic factor 2 ameliorates IMP compared to wild-type littermates RGD PMID:22326221 RGD:9587793 NCBI chr13:67,505,492...67,536,015
Ensembl chr13:64,955,503...64,986,277
JBrowse link
G Ncf2em1Mcwi neutrophil cytosolic factor 2; zinc finger nuclease induced mutant 1,Mcwi ameliorates IMP compared to wild-type littermates RGD PMID:22326221 RGD:9587793
G Nckap5 NCK-associated protein 5 IAGP RGD PMID:21257920 RGD:12798539 NCBI chr13:39,922,576...40,835,849
Ensembl chr13:37,370,792...38,283,268
JBrowse link
G Nox4 NADPH oxidase 4 severity IMP RGD PMID:26644237 RGD:11085830 NCBI chr 1:150,313,736...150,491,480
Ensembl chr 1:140,901,097...141,077,406
JBrowse link
G Optc opticin IAGP RGD PMID:23817491 RGD:12802368 NCBI chr13:47,906,145...47,920,334
Ensembl chr13:45,355,148...45,365,237
JBrowse link
G Pappa2 pappalysin 2 IMP RGD PMID:24714719 RGD:12792227 NCBI chr13:73,407,385...73,683,699
Ensembl chr13:70,876,794...71,147,779
JBrowse link
G Plekha6 pleckstrin homology domain containing A6 IAGP RGD PMID:23460292 RGD:12802369 NCBI chr13:47,166,899...47,307,003
Ensembl chr13:44,615,011...44,754,673
JBrowse link
G Plekha7 pleckstrin homology domain containing A7 ameliorates IMP compared to wild type RGD PMID:25136115 RGD:11079199 NCBI chr 1:179,798,856...179,982,155
Ensembl chr 1:170,365,135...170,547,775
JBrowse link
G Plekha7em4Mcwi pleckstrin homology domain containing, family A member 7; zinc finger nuclease induced mutant 4, Medical College of Wisconsin ameliorates IMP compared to wild type RGD PMID:25136115 RGD:11079199
G Prelp proline and arginine rich end leucine rich repeat protein IAGP RGD PMID:23817491 RGD:12802368 NCBI chr13:47,920,480...47,943,547
Ensembl chr13:45,370,533...45,380,270
JBrowse link
G Psme2-ps1 proteasome activator subunit 2, pseudogene 1 IAGP RGD PMID:21257920 RGD:12798539 NCBI chr13:40,742,081...40,742,929 JBrowse link
G Ptprv protein tyrosine phosphatase, receptor type, V IAGP RGD PMID:23460292 RGD:12802369 NCBI chr13:49,099,922...49,120,247
Ensembl chr13:46,548,128...46,568,329
JBrowse link
G Ren renin IAGP RGD PMID:23817491 RGD:12802368 NCBI chr13:47,348,312...47,359,539
Ensembl chr13:44,796,091...44,807,489
JBrowse link
G Resp18 regulated endocrine-specific protein 18 IMP RGD PMID:29570433 RGD:14348960 NCBI chr 9:84,213,844...84,220,186
Ensembl chr 9:76,764,590...76,778,722
JBrowse link
G Resp18em2Mcwi regulated endocrine-specific protein 18; zinc finger nuclease induced mutant 2, Medical College of Wisconsin IMP RGD PMID:29570433 RGD:14348960
G Rnpep arginyl aminopeptidase IAGP RGD PMID:23460292 RGD:12802369 NCBI chr13:49,251,259...49,271,440
Ensembl chr13:46,699,463...46,717,998
JBrowse link
G Sox13 SRY-box transcription factor 13 IAGP RGD PMID:23460292 RGD:12802369 NCBI chr13:47,383,145...47,427,572
Ensembl chr13:44,831,085...44,875,762
JBrowse link
G Syt2 synaptotagmin 2 IAGP RGD PMID:23460292 RGD:12802369 NCBI chr13:48,639,634...48,749,814
Ensembl chr13:46,185,282...46,193,859
JBrowse link
G Tmem163 transmembrane protein 163 IAGP RGD PMID:21257920 RGD:12798539 NCBI chr13:41,520,595...41,693,938
Ensembl chr13:38,968,101...39,141,452
JBrowse link
G Tnr tenascin R IMP RGD PMID:24714719 RGD:12792227 NCBI chr13:74,285,141...74,706,174
Ensembl chr13:72,091,585...72,167,641
JBrowse link
G Tuba1c-ps1 tubulin, alpha 1C, pseudogene 1 IAGP RGD PMID:21257920 RGD:12798539 NCBI chr13:41,060,047...41,061,387
Ensembl chr13:38,507,401...38,508,943
Ensembl chr13:38,507,401...38,508,943
JBrowse link
shortened QT interval term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rffl ring finger and FYVE-like domain containing E3 ubiquitin protein ligase IAGP as compared to SS/Jr RGD PMID:21357277 RGD:13442502 NCBI chr10:68,238,273...68,301,225
Ensembl chr10:67,740,712...67,824,434
JBrowse link
subarachnoid hemorrhage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccdc39 coiled-coil domain 39 molecular ruler complex subunit IMP RGD PMID:31771992 RGD:150521527 NCBI chr 2:118,593,881...118,631,584
Ensembl chr 2:116,665,261...116,703,350
JBrowse link
G Ccdc39em1Jgn coiled-coil domain containing 39; CRISPR/Cas9 induced mutant 1, Jgn IMP RGD PMID:31771992 RGD:150521527
thick interventricular septum term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lamp2 lysosomal-associated membrane protein 2 IMP in hemizygote mutant male (LAMP2y/-) RGD PMID:29720683 RGD:13703117 NCBI chr  X:122,038,734...122,087,745
Ensembl chr  X:117,057,606...117,260,522
JBrowse link
G Lamp2em1 lysosomal-associated membrane protein 2; TALEN induced mutant1 IMP in hemizygote mutant male (LAMP2y/-) RGD PMID:29720683 RGD:13703117
G Myh7b myosin heavy chain 7B IMP RGD PMID:32207065 RGD:126925946 NCBI chr 3:164,537,211...164,582,441
Ensembl chr 3:144,098,190...144,122,084
JBrowse link
G Myh7bem1Blar myosin heavy chain 7B; CRISPR/Cas9 induced mutant 1, Blar IMP RGD PMID:32207065 RGD:126925946
thick mitral valve term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gla galactosidase, alpha onset IMP compared to Wild type RGD PMID:29979634 RGD:401976416 NCBI chr  X:102,062,497...102,073,915
Ensembl chr  X:97,768,996...97,780,664
JBrowse link
G Glaem2Mcwi galactosidase, alpha; CRISPR/Cas9 system induced mutant 2, Medical College of Wisconsin onset IMP compared to Wild type RGD PMID:29979634 RGD:401976416
thick ventricular wall term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2b adenosine A2B receptor IMP RGD PMID:26385692 RGD:11533328 NCBI chr10:47,439,712...47,456,092
Ensembl chr10:46,940,384...46,956,772
JBrowse link
G Adora2bem2Mcwi adenosine A2B receptor; zinc finger nuclease induced mutant 2, Medical College of Wisconsin IMP RGD PMID:26385692 RGD:11533328
G Lamp2 lysosomal-associated membrane protein 2 IMP in hemizygote mutant male (LAMP2y/-) RGD PMID:29720683 RGD:13703117 NCBI chr  X:122,038,734...122,087,745
Ensembl chr  X:117,057,606...117,260,522
JBrowse link
G Lamp2em1 lysosomal-associated membrane protein 2; TALEN induced mutant1 IMP in hemizygote mutant male (LAMP2y/-) RGD PMID:29720683 RGD:13703117
thin ventricular wall term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts16 ADAM metallopeptidase with thrombospondin type 1 motif, 16 IMP As compared to SS parents RGD PMID:23185005 RGD:9685162 NCBI chr 1:34,258,899...34,388,952
Ensembl chr 1:32,430,436...32,560,494
JBrowse link
G Adamts16em1Bj ADAM metallopeptidase with thrombospondin type 1 motif, 16; ZFN mutant1,Bj IMP As compared to SS parents RGD PMID:23185005 RGD:9685162
G Ttn titin IAGP RGD PMID:27869827 RGD:11565821 NCBI chr 3:82,059,648...82,332,130
Ensembl chr 3:61,652,439...61,924,741
JBrowse link
G Ttnem2Sage Titin; zinc finger nuclease induced mutant 2,Sigma Advanced Genetic Engineering Labs IAGP RGD PMID:27869827 RGD:11565821
vascular smooth muscle hypertrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr2 bone morphogenetic protein receptor type 2 IMP RGD PMID:25593290 RGD:38500244 NCBI chr 9:68,685,942...68,801,353
Ensembl chr 9:61,190,566...61,301,809
JBrowse link
G Bmpr2em1Ang bone morphogenetic protein receptor type 2; ZFN induced mutant 1, Ang IMP RGD PMID:25593290 RGD:38500244
G Pld2 phospholipase D2 IDA angiotensin II induced RGD PMID:16113073 RGD:1642674 NCBI chr10:55,754,957...55,772,819
Ensembl chr10:55,256,359...55,272,808
JBrowse link
G Prkcz protein kinase C, zeta IDA angiotensin II induced RGD PMID:16113073 RGD:1642674 NCBI chr 5:171,101,774...171,212,694
Ensembl chr 5:165,819,466...165,930,367
JBrowse link

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  mammalian phenotype 5422
    cardiovascular system phenotype 1371
      abnormal cardiovascular system morphology + 427
      abnormal cardiovascular system physiology + 1149
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