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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:decreased susceptibility to autoimmune disorder
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Accession:MP:0005351 term browser browse the term
Definition:reduced likelihood that an organism will develop disease characterized by production of antibodies that react with host tissues or immune effector cells that are autoreactive to endogenous peptides
Synonyms:exact_synonym: increased resistance to autoimmune disorder;   reduced susceptibility to autoimmune disorder


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decreased susceptibility to autoimmune diabetes term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifnar1 interferon alpha and beta receptor subunit 1 IMP RGD PMID:27999109 RGD:12910492 NCBI chr11:30,725,774...30,752,227
Ensembl chr11:30,725,790...30,749,979 		JBrowse link
G Ifnar1em1 interferon alpha and beta receptor subunit 1; CRISPR/Cas9 induced mutant 1 IMP RGD PMID:27999109 RGD:12910492
G Ifnar1em2 interferon alpha and beta receptor subunit 1; CRISPR/Cas9 induced mutant 2 IMP RGD PMID:27999109 RGD:12910492
decreased susceptibility to experimental autoimmune myasthenia gravis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C6 complement C6 IAGP RGD PMID:17034580 RGD:1600670 NCBI chr 2:53,846,028...53,921,279
Ensembl chr 2:53,851,985...53,921,275 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5420
    immune system phenotype 519
      abnormal immune system physiology 384
        abnormal immune tolerance 116
          abnormal self tolerance 116
            autoimmune response 116
              abnormal susceptibility to autoimmune disorder 105
                decreased susceptibility to autoimmune disorder 62
                  decreased susceptibility to autoimmune diabetes 38
                  decreased susceptibility to autoimmune hemolytic anemia 0
                  decreased susceptibility to experimental autoimmune encephalomyelitis 8
                  decreased susceptibility to experimental autoimmune myasthenia gravis 1
                  decreased susceptibility to experimental autoimmune orchitis 0
                  decreased susceptibility to experimental autoimmune thyroiditis 0
                  decreased susceptibility to experimental autoimmune uveoretinitis 6
                  decreased susceptibility to induced arthritis 9
                  decreased susceptibility to systemic lupus erythematosus 0
paths to the root