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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:increased T cell proliferation
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Accession:MP:0005348 term browser browse the term
Definition:increase in the ability of a naive T cell population to undergo rapid expansion by cell division in response to stimuli
Synonyms:exact_synonym: T cell hyperproliferation;   enhanced T cell proliferation



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increased T cell proliferation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Themis thymocyte selection associated IAGP DNA:frameshift mutation: RGD PMID:22275874 RGD:38599149 NCBI chr 1:16,433,906...16,623,889
Ensembl chr 1:16,432,631...16,664,329
JBrowse link
G Themism1Adej thymocyte selection associated; mutant1, Adej IAGP compared to BN RGD PMID:22275874 RGD:38599149

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5402
    cellular phenotype 190
      abnormal cell physiology 145
        abnormal cell proliferation 25
          increased cell proliferation 18
            increased T cell proliferation 6
Path 2
Term Annotations click to browse term
  mammalian phenotype 5402
    immune system phenotype 502
      abnormal immune system physiology 384
        abnormal immune cell physiology 56
          abnormal leukocyte physiology 56
            abnormal lymphocyte physiology 49
              abnormal T cell physiology 14
                abnormal T cell activation 10
                  abnormal T cell proliferation 10
                    increased T cell proliferation 6
paths to the root