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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal myocardium layer morphology
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Accession:MP:0005329 term browser browse the term
Definition:any structural anomaly of the middle layer of the heart, comprised mainly of striated cardiac muscle fibers
Comment:Do not confuse cardiac muscle tissue with the myocardium. Myocardium consists primarily of cardiac muscle but these structures are not identical.
Synonyms:exact_synonym: abnormal myocardium morphology;   myocardial dysplasia


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decreased myocardial fiber size term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zbtb16 zinc finger and BTB domain containing 16 IMP compared to wild type SHR/OlaIpcv; RGD PMID:28396530 RGD:150340623 NCBI chr 8:48,989,376...49,177,011
Ensembl chr 8:48,994,566...49,177,011 		JBrowse link
G Zbtb16em1Ipcv zinc finger and BTB domain containing 16; TALEN induced mutant 1, Ipcv IMP compared to wild type SHR/OlaIpcv; RGD PMID:28396530 RGD:150340623
increased myocardial fiber size term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myh7b myosin heavy chain 7B IMP RGD PMID:32207065 RGD:126925946 NCBI chr 3:144,076,911...144,122,714
Ensembl chr 3:144,098,190...144,122,084 		JBrowse link
G Myh7bem1Blar myosin heavy chain 7B; CRISPR/Cas9 induced mutant 1, Blar IMP RGD PMID:32207065 RGD:126925946
myocardium steatosis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E IMP RGD PMID:28808185 RGD:13703132 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5402
    muscle phenotype 199
      abnormal muscle morphology 98
        abnormal cardiac muscle tissue morphology 59
          abnormal myocardium layer morphology 8
            abnormal atrium myocardium morphology + 0
            abnormal myocardial fiber morphology + 7
            abnormal myocardial trabeculae morphology + 0
            abnormal myocardium compact layer morphology + 0
            abnormal ventricle myocardium morphology + 0
            calcified myocardium 0
            disorganized myocardium + 0
            myocardium hypertrophy 0
            myocardium hypoplasia + 0
            myocardium necrosis 0
            myocardium steatosis 1
            thick myocardium 0
            thin myocardium 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5402
    cardiovascular system phenotype 1371
      abnormal cardiovascular system morphology 427
        abnormal heart morphology 331
          abnormal heart layer morphology 8
            abnormal myocardium layer morphology 8
              abnormal atrium myocardium morphology + 0
              abnormal myocardial fiber morphology + 7
              abnormal myocardial trabeculae morphology + 0
              abnormal myocardium compact layer morphology + 0
              abnormal ventricle myocardium morphology + 0
              calcified myocardium 0
              disorganized myocardium + 0
              myocardium hypertrophy 0
              myocardium hypoplasia + 0
              myocardium necrosis 0
              myocardium steatosis 1
              thick myocardium 0
              thin myocardium 0
paths to the root