Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal blood-brain barrier function
go back to main search page
Accession:MP:0005167 term browser browse the term
Definition:anomaly in the function of the group of barriers and transport systems in the brain capillary endothelium that controls the entrance of substances into the brain extracellular space from the blood
Synonyms:exact_synonym: abnormal BBB function



show annotations for term's descendants           Sort by:
abnormal blood-brain barrier function term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A IMP RGD PMID:22049154 RGD:8657330 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcb1aem2Sage ATP binding cassette subfamily B member 1A; ZFN induced mutant 2, Sage IMP RGD PMID:22049154 RGD:8657330
G Abcc2 ATP binding cassette subfamily C member 2 IAGP RGD PMID:12663688 RGD:704399 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Crh corticotropin releasing hormone IDA RGD PMID:12663088 RGD:704425 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5369
    nervous system phenotype 360
      abnormal nervous system physiology 205
        abnormal blood-brain barrier function 6
          enhanced blood-brain barrier function 0
          impaired blood-brain barrier function 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5369
    cardiovascular system phenotype 1356
      abnormal cardiovascular system physiology 1132
        abnormal vasculature physiology 63
          abnormal blood vessel physiology 63
            abnormal blood-brain barrier function 6
              enhanced blood-brain barrier function 0
              impaired blood-brain barrier function 0
paths to the root