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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:cyclopia
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Accession:MP:0005163 term browser browse the term
Definition:a congenital defect characterized by the failure of the embryonic prosencephalon to properly divide the orbits of the eye into two cavities; cyclopia is a rare form of holoprosencephaly that typically presents with a median single eye or a partially divided eye in a single orbit, absent nose, and a proboscis above the eye
Synonyms:exact_synonym: Cyclops eye;   cyclocephaly;   cyclopea;   one eye;   single central eye;   synophthalmia;   synophthalmus


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cyclopia term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr2a activin receptor IIA IAGP MGI PMID:10452853 NCBI chr 2:48,704,121...48,793,276
Ensembl chr 2:48,704,121...48,793,281 		JBrowse link
G Bmpr1a bone morphogenetic protein receptor, type 1A IAGP MGI PMID:20730911 NCBI chr14:34,133,018...34,225,335
Ensembl chr14:34,132,691...34,225,298 		JBrowse link
G Chrd chordin IAGP MGI PMID:10688202 NCBI chr16:20,551,528...20,561,132
Ensembl chr16:20,551,877...20,561,134 		JBrowse link
G Col2a1 collagen, type II, alpha 1 IAGP MGI PMID:20730911 NCBI chr15:97,873,483...97,902,525
Ensembl chr15:97,873,483...97,902,576 		JBrowse link
G Cripto cripto, EGF-CFC family member IAGP MGI PMID:16291788 NCBI chr 9:110,768,676...110,775,226
Ensembl chr 9:110,768,671...110,775,226 		JBrowse link
G Crkl v-crk avian sarcoma virus CT10 oncogene homolog-like IAGP MGI PMID:23469164 PMID:25565927 NCBI chr16:17,269,849...17,305,304
Ensembl chr16:17,269,851...17,305,298 		JBrowse link
G Disp1 dispatched RND transporter family member 1 IAGP MGI PMID:12421714 NCBI chr 1:182,867,828...183,010,257
Ensembl chr 1:182,867,830...183,003,086 		JBrowse link
G Edil3 EGF-like repeats and discoidin I-like domains 3 IAGP MGI PMID:22383895 NCBI chr13:88,969,591...89,471,344
Ensembl chr13:88,969,591...89,471,342 		JBrowse link
G Fat1 FAT atypical cadherin 1 IAGP MGI PMID:12724416 NCBI chr 8:45,386,137...45,505,294
Ensembl chr 8:45,388,484...45,505,294 		JBrowse link
G Foxh1 forkhead box H1 IEA MGI NCBI chr15:76,552,029...76,554,286
Ensembl chr15:76,552,425...76,554,148 		JBrowse link
G Foxq1 forkhead box Q1 IAGP MGI PMID:16109771 NCBI chr13:31,742,153...31,744,959
Ensembl chr13:31,740,117...31,744,959 		JBrowse link
G Gli2 GLI-Kruppel family member GLI2 IAGP MGI PMID:11748151 NCBI chr 1:118,761,791...118,987,578
Ensembl chr 1:118,761,862...118,981,349 		JBrowse link
G Nodal nodal growth differentiation factor IAGP MGI PMID:9655392 PMID:10452853 NCBI chr10:61,253,751...61,261,117
Ensembl chr10:61,253,751...61,261,117 		JBrowse link
G Nog noggin IAGP MGI PMID:10688202 NCBI chr11:89,191,464...89,193,385
Ensembl chr11:89,191,464...89,193,158 		JBrowse link
G Nosip nitric oxide synthase interacting protein IAGP MGI PMID:25546391 NCBI chr 7:44,711,840...44,727,927
Ensembl chr 7:44,711,853...44,727,634 		JBrowse link
G Pcsk6 proprotein convertase subtilisin/kexin type 6 IAGP MGI PMID:10809672 NCBI chr 7:65,511,884...65,700,134
Ensembl chr 7:65,511,482...65,700,134 		JBrowse link
G Pgap1 post-GPI attachment to proteins 1 IAGP MGI PMID:4019727 PMID:10529425 NCBI chr 1:54,512,159...54,596,843
Ensembl chr 1:54,512,153...54,596,843 		JBrowse link
G Shh sonic hedgehog IAGP MGI PMID:8270769 PMID:8837770 PMID:11748151 PMID:15105374 PMID:15576405 NCBI chr 5:28,661,838...28,672,099
Ensembl chr 5:28,661,813...28,672,254 		JBrowse link
G Smad2 SMAD family member 2 IAGP MGI PMID:9655392 PMID:15183723 NCBI chr18:76,369,898...76,444,819
Ensembl chr18:76,374,651...76,444,034 		JBrowse link
G Smad3 SMAD family member 3 IAGP MGI PMID:15183723 NCBI chr 9:63,554,048...63,665,276
Ensembl chr 9:63,554,049...63,665,276 		JBrowse link
G Spry2 sprouty RTK signaling antagonist 2 IAGP MGI PMID:17156747 NCBI chr14:106,129,381...106,134,559
Ensembl chr14:106,129,381...106,134,253 		JBrowse link
G Spry4 sprouty RTK signaling antagonist 4 IAGP MGI PMID:17156747 NCBI chr18:38,719,300...38,734,400
Ensembl chr18:38,719,300...38,734,468 		JBrowse link
G Tgif1 TGFB-induced factor homeobox 1 IAGP MGI PMID:22383895 NCBI chr17:71,151,200...71,160,527
Ensembl chr17:71,151,200...71,160,541 		JBrowse link
G Tgif2 TGFB-induced factor homeobox 2 IAGP MGI PMID:22383895 NCBI chr 2:156,681,737...156,697,490
Ensembl chr 2:156,681,927...156,697,490 		JBrowse link
G Twsg1 twisted gastrulation BMP signaling modulator 1 IAGP MGI PMID:15013800 NCBI chr17:66,230,060...66,258,198
Ensembl chr17:66,228,967...66,258,221 		JBrowse link
G Wdr11 WD repeat domain 11 IAGP MGI PMID:29263200 NCBI chr 7:129,193,373...129,237,462
Ensembl chr 7:129,193,587...129,237,462 		JBrowse link
G Zeb1 zinc finger E-box binding homeobox 1 IAGP MGI PMID:28176446 NCBI chr18:5,591,330...5,775,468
Ensembl chr18:5,591,860...5,775,467 		JBrowse link
G Zic2 zinc finger protein of the cerebellum 2 IAGP MGI PMID:18617531 PMID:29992973 NCBI chr14:122,712,796...122,717,740
Ensembl chr14:122,712,847...122,717,264 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 17097
    vision/eye phenotype 3192
      abnormal eye morphology 3033
        abnormal eye distance/ position 120
          cyclopia 28
paths to the root