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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal T cell proliferation
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Accession:MP:0005094 term browser browse the term
Definition:anomaly in the ability of a naive T cell population to undergo rapid expansion by cell division in response to stimuli



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decreased T cell proliferation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd247 Cd247 molecule IMP compared to wild-type RGD PMID:24343121 RGD:13442481 NCBI chr13:78,043,302...78,118,437
Ensembl chr13:78,043,307...78,122,263
JBrowse link
G Cd247em1Mcwi Cd247 molecule; zinc finger nuclease induced mutant 1, Medical College of Wisconsin IMP RGD PMID:24343121 RGD:13442481
increased T cell proliferation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Themis thymocyte selection associated IAGP DNA:frameshift mutation: RGD PMID:22275874 RGD:38599149 NCBI chr 1:16,433,906...16,623,889
Ensembl chr 1:16,432,631...16,664,329
JBrowse link
G Themism1Adej thymocyte selection associated; mutant1, Adej IAGP compared to BN RGD PMID:22275874 RGD:38599149

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5368
    cellular phenotype 167
      abnormal cell physiology 137
        abnormal cell proliferation 24
          abnormal T cell proliferation 9
            decreased T cell proliferation 3
            increased T cell proliferation 6
Path 2
Term Annotations click to browse term
  mammalian phenotype 5368
    immune system phenotype 492
      abnormal immune system physiology 377
        abnormal adaptive immunity 59
          abnormal leukocyte physiology 55
            abnormal lymphocyte physiology 48
              abnormal T cell physiology 13
                abnormal T cell activation 9
                  abnormal T cell proliferation 9
                    decreased T cell proliferation 3
                    increased T cell proliferation 6
paths to the root