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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:increased double-negative T cell number
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Accession:MP:0005090 term browser browse the term
Definition:greater than expected numbers of the subset of T cells found in the thymus that express neither CD4 nor CD8
Synonyms:exact_synonym: increased CD4-CD8- T cell count;   increased double-negative T cell count;   increased double-negative T cell numbers;   increased numbers of CD4-CD8- T cells;   increased numbers of double-negative T cells



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increased double-negative T cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
Q Neudeg2 Neurodegradation QTL 2 IAGP RGD PMID:14586010 RGD:1358788 NCBI chr 5:24,838,710...44,045,280 JBrowse link
Q Neuinf1 Neuroinflammation QTL 1 IAGP RGD PMID:14586010 RGD:1358788 NCBI chr 5:154,828,214...166,875,058 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5419
    immune system phenotype 502
      abnormal immune system morphology 194
        abnormal immune system cell morphology 154
          abnormal leukopoiesis 18
            abnormal lymphopoiesis 18
              abnormal T cell differentiation 18
                abnormal double-negative T cell morphology 2
                  increased double-negative T cell number 2
                    increased DN1 thymic pro-T cell number 0
                    increased DN2 thymocyte number 0
                    increased DN3 thymocyte number 0
                    increased DN4 thymocyte number 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5419
    hematopoietic system phenotype 250
      abnormal hematopoietic system morphology/development 230
        abnormal hematopoietic cell morphology 186
          abnormal blood cell morphology 99
            abnormal hemopoiesis 18
              abnormal definitive hematopoiesis 18
                abnormal leukopoiesis 18
                  abnormal lymphopoiesis 18
                    abnormal T cell differentiation 18
                      abnormal double-negative T cell morphology 2
                        increased double-negative T cell number 2
                          increased DN1 thymic pro-T cell number 0
                          increased DN2 thymocyte number 0
                          increased DN3 thymocyte number 0
                          increased DN4 thymocyte number 0
paths to the root