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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal cytotoxic T cell physiology
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Accession:MP:0005078 term browser browse the term
Definition:any functional anomaly of the subset of CD8-positive T lymphocytes capable of directly killing appropriately targeted cells
Synonyms:exact_synonym: CTL dysfunction;   cytotoxic T cell dysfunction;   cytotoxic T lymphocyte dysfunction



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  mammalian phenotype 5418
    immune system phenotype 502
      abnormal immune system physiology 384
        abnormal immune cell physiology 56
          abnormal leukocyte physiology 56
            abnormal lymphocyte physiology 49
              abnormal T cell physiology 14
                abnormal CD8-positive, alpha-beta T cell physiology 0
                  abnormal cytotoxic T cell physiology 0
                    abnormal cytotoxic T cell cytolysis + 0
                    decreased cytotoxic T cell apoptosis 0
                    increased cytotoxic T cell apoptosis 0
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