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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal T cell clonal deletion
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Accession:MP:0005002 term browser browse the term
Definition:a defect in the process of removal of immature T lymphocytes that interact with self antigens during maturation
Synonyms:exact_synonym: T cell clonal deletion abnormalities;   T lymphocyte clonal deletion abnormalities


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abnormal T cell clonal deletion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd28 CD28 antigen IAGP MGI PMID:11342622 NCBI chr 1:60,785,547...60,812,521
Ensembl chr 1:60,755,959...60,812,518 		JBrowse link
G Cd40lg CD40 ligand IAGP MGI PMID:11342622 NCBI chr  X:56,257,448...56,269,402
Ensembl chr  X:56,257,503...56,269,402 		JBrowse link
G Cd5 CD5 antigen IAGP MGI PMID:11342622 NCBI chr19:10,695,471...10,716,390
Ensembl chr19:10,694,480...10,716,366 		JBrowse link
G Fas Fas cell surface death receptor IAGP MGI PMID:8700897 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172 		JBrowse link
G Fyn Fyn proto-oncogene IAGP MGI PMID:1387588 NCBI chr10:39,245,735...39,441,377
Ensembl chr10:39,244,851...39,441,377 		JBrowse link
G Il2rb interleukin 2 receptor, beta chain IAGP MGI PMID:12196288 NCBI chr15:78,363,456...78,396,569
Ensembl chr15:78,363,456...78,379,471 		JBrowse link
G Il6st interleukin 6 signal transducer IAGP MGI PMID:12370259 NCBI chr13:112,600,604...112,643,394
Ensembl chr13:112,600,604...112,646,620 		JBrowse link
G Trap1a tumor rejection antigen P1A IAGP MGI PMID:22140254 NCBI chr  X:138,234,432...138,238,918
Ensembl chr  X:138,234,432...138,238,918 		JBrowse link
G Zap70 zeta-chain (TCR) associated protein kinase IAGP MGI PMID:19841086 NCBI chr 1:36,800,912...36,821,899
Ensembl chr 1:36,800,879...36,821,899 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 17065
    immune system phenotype 5763
      abnormal immune system physiology 3496
        abnormal immune tolerance 666
          abnormal clonal deletion 14
            abnormal T cell clonal deletion 14
Path 2
Term Annotations click to browse term
  mammalian phenotype 17065
    hematopoietic system phenotype 5603
      abnormal hematopoietic system morphology/development 5129
        abnormal hematopoietic cell morphology 4306
          abnormal blood cell morphology 3212
            abnormal hemopoiesis 1160
              abnormal definitive hematopoiesis 1133
                abnormal leukopoiesis 872
                  abnormal lymphopoiesis 749
                    abnormal T cell differentiation 490
                      abnormal T cell selection 57
                        abnormal negative T cell selection 32
                          abnormal T cell clonal deletion 14
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