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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal CD8-positive, alpha-beta T cell physiology
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Accession:MP:0004392 term browser browse the term
Definition:any functional anomaly of the subset of T lymphocytes that express the CD8 marker on the cell surface
Synonyms:exact_synonym: abnormal CD8+ T cell physiology;   abnormal CD8-positive T cell physiology
 broad_synonym: abnormal single positive T cell physiology



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abnormal CD8-positive, alpha-beta T cell physiology term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agk acylglycerol kinase IAGP MGI PMID:31204281 NCBI chr 6:40,302,010...40,378,723
Ensembl chr 6:40,302,106...40,373,696
JBrowse link
G B2m beta-2 microglobulin IAGP MGI PMID:16493087 NCBI chr 2:121,978,168...121,983,563
Ensembl chr 2:121,978,167...121,983,564
JBrowse link
G Bbc3 BCL2 binding component 3 IAGP MGI PMID:18287039 NCBI chr 7:16,042,307...16,052,130
Ensembl chr 7:16,042,318...16,052,130
JBrowse link
G Bcl2l11 BCL2 like 11 IAGP MGI PMID:18287039 NCBI chr 2:127,967,958...128,004,467
Ensembl chr 2:127,967,958...128,004,467
JBrowse link
G Casp8 caspase 8 IAGP MGI PMID:12654726 NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662
JBrowse link
G Cd19 CD19 antigen IAGP MGI PMID:19620304 PMID:22341446 NCBI chr 7:126,007,620...126,016,401
Ensembl chr 7:126,007,622...126,014,061
JBrowse link
G Cd274 CD274 antigen IAGP MGI PMID:15030776 NCBI chr19:29,339,428...29,365,495
Ensembl chr19:29,344,855...29,365,495
JBrowse link
G Cd302 CD302 antigen IAGP MGI PMID:27316686 NCBI chr 2:60,082,337...60,114,828
Ensembl chr 2:60,082,337...60,114,832
JBrowse link
G Cd3g CD3 antigen, gamma polypeptide IAGP MGI PMID:11160319 NCBI chr 9:44,880,870...44,891,729
Ensembl chr 9:44,880,870...44,891,729
JBrowse link
G Cd70 CD70 antigen IAGP MGI PMID:23269247 NCBI chr17:57,452,997...57,456,777
Ensembl chr17:57,452,997...57,456,777
JBrowse link
G Cd8a CD8 subunit alpha IEA MGI NCBI chr 6:71,350,411...71,356,155
Ensembl chr 6:71,350,411...71,356,157
JBrowse link
G Erap1 endoplasmic reticulum aminopeptidase 1 IAGP MGI PMID:16299505 PMID:16505142 PMID:17128277 NCBI chr13:74,787,692...74,841,321
Ensembl chr13:74,787,687...74,841,320
JBrowse link
G Foxo1 forkhead box O1 IAGP MGI PMID:19285438 NCBI chr 3:52,175,758...52,257,530
Ensembl chr 3:52,175,757...52,260,642
JBrowse link
G Foxp3 forkhead box P3 IAGP MGI PMID:17220876 NCBI chr  X:7,445,915...7,461,482
Ensembl chr  X:7,439,883...7,461,484
JBrowse link
G G6pc2 glucose-6-phosphatase, catalytic, 2 IAGP MGI PMID:20439719 NCBI chr 2:69,041,417...69,058,337
Ensembl chr 2:69,041,417...69,058,185
JBrowse link
G Gimap1 GTPase, IMAP family member 1 IAGP MGI PMID:20194894 NCBI chr 6:48,715,981...48,720,729
Ensembl chr 6:48,715,988...48,720,729
JBrowse link
G Git2 GIT ArfGAP 2 IAGP MGI PMID:20431621 NCBI chr 5:114,865,469...114,912,647
Ensembl chr 5:114,865,468...114,913,578
JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:22341446 PMID:23243279 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,054,294
JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 IAGP MGI PMID:22875804 NCBI chr11:46,345,758...46,372,082
Ensembl chr11:46,345,762...46,372,082
JBrowse link
G Hsh2d hematopoietic SH2 domain containing IAGP MGI PMID:16880512 NCBI chr 8:72,943,512...72,954,802
Ensembl chr 8:72,943,482...72,955,371
JBrowse link
G Ifnar1 interferon (alpha and beta) receptor 1 IAGP MGI PMID:10209048 NCBI chr16:91,281,016...91,307,411
Ensembl chr16:91,282,126...91,304,329
JBrowse link
G Il10 interleukin 10 IAGP MGI PMID:19620304 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
JBrowse link
G Il12b interleukin 12b IAGP MGI PMID:16688182 NCBI chr11:44,290,890...44,305,504
Ensembl chr11:44,290,890...44,304,860
JBrowse link
G Il15 interleukin 15 IAGP MGI PMID:15630141 NCBI chr 8:83,058,253...83,129,883
Ensembl chr 8:83,058,261...83,129,851
JBrowse link
G Il21r interleukin 21 receptor IAGP MGI PMID:15630141 NCBI chr 7:125,202,424...125,232,742
Ensembl chr 7:125,202,601...125,232,742
JBrowse link
G Il23a interleukin 23, alpha subunit p19 IAGP MGI PMID:16688182 NCBI chr10:128,132,009...128,133,953
Ensembl chr10:128,132,008...128,134,621
JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D IAGP MGI PMID:10606629 NCBI chr 1:87,548,034...87,648,232
Ensembl chr 1:87,548,034...87,648,229
JBrowse link
G Itk IL2 inducible T cell kinase IAGP MGI PMID:16860759 NCBI chr11:46,215,975...46,280,342
Ensembl chr11:46,215,977...46,280,342
JBrowse link
G Lag3 lymphocyte-activation gene 3 IAGP MGI PMID:28783703 NCBI chr 6:124,881,322...124,888,668
Ensembl chr 6:124,881,324...124,888,668
JBrowse link
G Lat2 linker for activation of T cells family, member 2 IAGP MGI PMID:17081783 NCBI chr 5:134,628,957...134,648,637
Ensembl chr 5:134,628,876...134,643,879
JBrowse link
G Layn layilin IAGP MGI PMID:32539073 NCBI chr 9:50,966,323...50,988,501
Ensembl chr 9:50,965,940...50,988,394
JBrowse link
G Mcl1 myeloid cell leukemia sequence 1 IAGP MGI PMID:19234191 NCBI chr 3:95,564,017...95,583,553
Ensembl chr 3:95,566,099...95,570,487
JBrowse link
G Myh9 myosin, heavy polypeptide 9, non-muscle IAGP MGI PMID:20835229 NCBI chr15:77,644,788...77,726,315
Ensembl chr15:77,644,787...77,726,375
JBrowse link
G Notch2 notch 2 IAGP MGI PMID:18724371 NCBI chr 3:97,920,854...98,057,683
Ensembl chr 3:97,920,843...98,057,677
JBrowse link
G Pdcd1lg2 programmed cell death 1 ligand 2 IAGP MGI PMID:16606670 NCBI chr19:29,388,319...29,450,327
Ensembl chr19:29,388,319...29,448,561
JBrowse link
G Pgd phosphogluconate dehydrogenase IAGP MGI PMID:33691103 NCBI chr 4:149,234,448...149,251,162
Ensembl chr 4:149,234,448...149,251,228
JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma IAGP MGI PMID:18250413 NCBI chr12:32,223,128...32,258,675
Ensembl chr12:32,223,472...32,258,658
JBrowse link
G Ppp3cb protein phosphatase 3, catalytic subunit, beta isoform IEA MGI NCBI chr14:20,549,432...20,596,641
Ensembl chr14:20,549,432...20,596,641
JBrowse link
G Prkd2 protein kinase D2 IAGP MGI PMID:20819079 NCBI chr 7:16,576,827...16,604,386
Ensembl chr 7:16,576,827...16,604,389
JBrowse link
G Psme2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) IAGP MGI PMID:10591649 NCBI chr14:55,824,897...55,828,558
Ensembl chr14:55,824,898...55,828,570
JBrowse link
G Pten phosphatase and tensin homolog IAGP MGI PMID:20823247 NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560
JBrowse link
G Pvrig poliovirus receptor related immunoglobulin domain containing IAGP MGI PMID:30659055 NCBI chr 5:138,340,193...138,346,953
Ensembl chr 5:138,340,223...138,341,819
JBrowse link
G Rag2 recombination activating gene 2 IAGP MGI PMID:17873878 NCBI chr 2:101,455,057...101,462,873
Ensembl chr 2:101,455,063...101,462,874
JBrowse link
G Rras2 related RAS viral (r-ras) oncogene 2 IAGP MGI PMID:19561613 NCBI chr 7:113,646,017...113,717,016
Ensembl chr 7:113,646,017...113,717,016
JBrowse link
G Snrnp40 small nuclear ribonucleoprotein 40 (U5) IAGP MGI PMID:31427773 NCBI chr 4:130,253,925...130,283,826
Ensembl chr 4:130,253,925...130,283,819
JBrowse link
G Stk4 serine/threonine kinase 4 IAGP MGI PMID:19692642 NCBI chr 2:163,916,033...163,997,444
Ensembl chr 2:163,912,242...163,997,444
JBrowse link
G Trap1a tumor rejection antigen P1A IAGP MGI PMID:22140254 NCBI chr  X:138,234,432...138,238,918
Ensembl chr  X:138,234,432...138,238,918
JBrowse link
G Txk TXK tyrosine kinase IAGP MGI PMID:16860759 NCBI chr 5:72,853,321...72,910,337
Ensembl chr 5:72,853,321...72,910,120
JBrowse link
G Vav1 vav 1 oncogene IAGP MGI PMID:20009105 NCBI chr17:57,586,080...57,636,236
Ensembl chr17:57,586,100...57,635,031
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 IAGP MGI PMID:11257140 NCBI chr 3:115,903,669...115,923,337
Ensembl chr 3:115,903,598...115,923,337
JBrowse link
G Xcl1 chemokine (C motif) ligand 1 IAGP MGI PMID:19913446 NCBI chr 1:164,759,216...164,763,094
Ensembl chr 1:164,759,213...164,763,096
JBrowse link
G Xcr1 chemokine (C motif) receptor 1 IAGP MGI PMID:23670193 NCBI chr 9:123,681,380...123,691,094
Ensembl chr 9:123,681,380...123,691,094
JBrowse link
abnormal cytotoxic T cell cytolysis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itgb2 integrin beta 2 IEA MGI NCBI chr10:77,366,164...77,401,542
Ensembl chr10:77,366,086...77,401,542
JBrowse link
abnormal cytotoxic T cell physiology term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B2m beta-2 microglobulin IAGP MGI PMID:2139497 PMID:16493087 NCBI chr 2:121,978,168...121,983,563
Ensembl chr 2:121,978,167...121,983,564
JBrowse link
G Batf3 basic leucine zipper transcription factor, ATF-like 3 IAGP MGI PMID:19008445 PMID:22209163 NCBI chr 1:190,830,611...190,841,140
Ensembl chr 1:190,830,044...190,841,142
JBrowse link
G Bcl10 B cell leukemia/lymphoma 10 IAGP MGI PMID:11163238 NCBI chr 3:145,630,017...145,640,121
Ensembl chr 3:145,628,559...145,640,111
JBrowse link
G Bcl3 B cell leukemia/lymphoma 3 IAGP MGI PMID:9133427 NCBI chr 7:19,542,387...19,556,691
Ensembl chr 7:19,542,387...19,556,695
JBrowse link
G Card11 caspase recruitment domain family, member 11 IEA MGI NCBI chr 5:140,858,109...140,986,398
Ensembl chr 5:140,858,745...140,986,337
JBrowse link
G Cd27 CD27 antigen IAGP MGI PMID:11062504 NCBI chr 6:125,209,583...125,214,014
Ensembl chr 6:125,209,585...125,213,973
JBrowse link
G Cd28 CD28 antigen IAGP MGI PMID:10528184 PMID:12752681 NCBI chr 1:60,785,547...60,812,521
Ensembl chr 1:60,755,959...60,812,518
JBrowse link
G Cd8a CD8 subunit alpha IAGP MGI PMID:1673361 NCBI chr 6:71,350,411...71,356,155
Ensembl chr 6:71,350,411...71,356,157
JBrowse link
G Cd8b1 CD8 subunit beta 1 IAGP MGI PMID:7889415 NCBI chr 6:71,299,772...71,314,476
Ensembl chr 6:71,299,772...71,314,478
JBrowse link
G Ctsc cathepsin C IAGP MGI PMID:10411926 NCBI chr 7:87,927,233...87,960,083
Ensembl chr 7:87,927,293...87,960,096
JBrowse link
G Dicer1 dicer 1, ribonuclease type III IAGP MGI PMID:16009718 NCBI chr12:104,654,001...104,718,331
Ensembl chr12:104,654,001...104,718,211
JBrowse link
G Ebag9 estrogen receptor-binding fragment-associated gene 9 IAGP MGI PMID:19620783 NCBI chr15:44,482,574...44,504,916
Ensembl chr15:44,482,571...44,504,911
JBrowse link
G Erap1 endoplasmic reticulum aminopeptidase 1 IAGP MGI PMID:16754858 PMID:17277129 NCBI chr13:74,787,692...74,841,321
Ensembl chr13:74,787,687...74,841,320
JBrowse link
G Fas Fas cell surface death receptor IAGP MGI PMID:6610701 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172
JBrowse link
G Fasl Fas ligand IAGP MGI PMID:19794494 NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064
JBrowse link
G Gzmb granzyme B IAGP MGI PMID:16618603 NCBI chr14:56,496,293...56,499,791
Ensembl chr14:56,496,295...56,499,717
JBrowse link
G H2-D1 histocompatibility 2, D region locus 1 IAGP MGI PMID:16476767 NCBI chr17:35,482,070...35,486,473
Ensembl chr17:35,481,706...35,486,475
JBrowse link
G H2-M3 histocompatibility 2, M region locus 3 IAGP MGI PMID:16476767 NCBI chr17:37,581,094...37,585,380
Ensembl chr17:37,581,111...37,585,375
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 IAGP MGI PMID:10953035 NCBI chr  X:52,076,955...52,110,537
Ensembl chr  X:52,077,014...52,110,536
JBrowse link
G Ifnar2 interferon (alpha and beta) receptor 2 IAGP MGI PMID:18256672 NCBI chr16:91,166,517...91,202,477
Ensembl chr16:91,169,671...91,202,477
JBrowse link
G Ifng interferon gamma IAGP MGI PMID:9653090 PMID:11714835 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
JBrowse link
G Ifngr1 interferon gamma receptor 1 IAGP MGI PMID:8456301 NCBI chr10:19,467,697...19,485,977
Ensembl chr10:19,467,697...19,485,977
JBrowse link
G Ifngr2 interferon gamma receptor 2 IAGP MGI PMID:11714835 NCBI chr16:91,343,947...91,360,895
Ensembl chr16:91,343,960...91,362,511
JBrowse link
G Il20rb interleukin 20 receptor beta IAGP MGI PMID:19124723 NCBI chr 9:100,339,772...100,368,526
Ensembl chr 9:100,339,772...100,368,841
JBrowse link
G Immp2l IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) IAGP MGI PMID:8786307 NCBI chr12:41,074,060...42,002,371
Ensembl chr12:41,074,089...42,002,371
JBrowse link
G Impdh1 inosine monophosphate dehydrogenase 1 IAGP MGI PMID:12944494 NCBI chr 6:29,200,435...29,216,363
Ensembl chr 6:29,200,433...29,216,363
JBrowse link
G Impdh2 inosine monophosphate dehydrogenase 2 IAGP MGI PMID:10953035 PMID:12944494 NCBI chr 9:108,437,635...108,442,776
Ensembl chr 9:108,437,485...108,442,783
JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D IAGP MGI PMID:17585010 NCBI chr 1:87,548,034...87,648,232
Ensembl chr 1:87,548,034...87,648,229
JBrowse link
G Irf8 interferon regulatory factor 8 IAGP MGI PMID:8861914 NCBI chr 8:121,463,097...121,483,433
Ensembl chr 8:121,463,097...121,483,433
JBrowse link
G Itgal integrin alpha L IAGP MGI PMID:8955185 NCBI chr 7:126,895,404...126,934,309
Ensembl chr 7:126,895,432...126,934,310
JBrowse link
G Lmbr1l limb region 1 like IAGP MGI PMID:31073040 NCBI chr15:98,801,798...98,815,944
Ensembl chr15:98,801,798...98,816,112
JBrowse link
G Ly75 lymphocyte antigen 75 IAGP MGI PMID:15024047 NCBI chr 2:60,122,447...60,213,617
Ensembl chr 2:60,122,447...60,213,647
JBrowse link
G Notch2 notch 2 IAGP MGI PMID:18724371 NCBI chr 3:97,920,854...98,057,683
Ensembl chr 3:97,920,843...98,057,677
JBrowse link
G Pdcd1lg2 programmed cell death 1 ligand 2 IAGP MGI PMID:15897272 NCBI chr19:29,388,319...29,450,327
Ensembl chr19:29,388,319...29,448,561
JBrowse link
G Pgd phosphogluconate dehydrogenase IAGP MGI PMID:33691103 NCBI chr 4:149,234,448...149,251,162
Ensembl chr 4:149,234,448...149,251,228
JBrowse link
G Pla2g2d phospholipase A2, group IID IAGP MGI PMID:26392224 NCBI chr 4:138,503,046...138,509,363
Ensembl chr 4:138,503,046...138,509,357
JBrowse link
G Prf1 perforin 1 (pore forming protein) IAGP MGI PMID:23160464 NCBI chr10:61,133,530...61,140,463
Ensembl chr10:61,133,612...61,140,459
JBrowse link
G Psmb10 proteasome (prosome, macropain) subunit, beta type 10 IAGP MGI PMID:16709825 NCBI chr 8:106,662,360...106,665,024
Ensembl chr 8:106,662,367...106,665,076
JBrowse link
G Ptprcap protein tyrosine phosphatase receptor type C polypeptide-associated protein IAGP MGI PMID:9607926 NCBI chr19:4,204,645...4,206,709
Ensembl chr19:4,203,603...4,206,750
JBrowse link
G Rab27a RAB27A, member RAS oncogene family IAGP MGI PMID:23160464 NCBI chr 9:72,952,092...73,004,905
Ensembl chr 9:72,952,136...73,004,911
JBrowse link
G Rac2 Rac family small GTPase 2 IEA MGI NCBI chr15:78,443,369...78,456,983
Ensembl chr15:78,443,367...78,456,983
JBrowse link
G Rag2 recombination activating gene 2 IAGP MGI PMID:9341770 PMID:11163198 NCBI chr 2:101,455,057...101,462,873
Ensembl chr 2:101,455,063...101,462,874
JBrowse link
G Relb avian reticuloendotheliosis viral (v-rel) oncogene related B IAGP MGI PMID:9164938 NCBI chr 7:19,340,142...19,363,352
Ensembl chr 7:19,340,142...19,363,363
JBrowse link
G Serpinb9 serine (or cysteine) peptidase inhibitor, clade B, member 9 IAGP MGI PMID:16618603 NCBI chr13:33,181,044...33,201,938
Ensembl chr13:33,187,233...33,201,940
JBrowse link
G Sh2d1a SH2 domain containing 1A IAGP MGI PMID:22683123 NCBI chr  X:41,591,442...41,610,974
Ensembl chr  X:41,591,330...41,618,207
JBrowse link
G Stat4 signal transducer and activator of transcription 4 IAGP MGI PMID:10553062 NCBI chr 1:52,026,265...52,146,348
Ensembl chr 1:52,026,307...52,146,348
JBrowse link
G Stat6 signal transducer and activator of transcription 6 IAGP MGI PMID:11086031 NCBI chr10:127,478,855...127,496,856
Ensembl chr10:127,478,855...127,496,826
JBrowse link
G Stx11 syntaxin 11 IAGP MGI PMID:23160464 NCBI chr10:12,813,961...12,840,242
Ensembl chr10:12,813,953...12,840,042
JBrowse link
G Tagln2 transgelin 2 IAGP MGI PMID:25869671 NCBI chr 1:172,327,813...172,334,942
Ensembl chr 1:172,327,614...172,334,947
JBrowse link
G Tap2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) IEA MGI NCBI chr17:34,423,453...34,435,295
Ensembl chr17:34,422,501...34,435,295
JBrowse link
G Tapbp TAP binding protein IAGP MGI PMID:10981964 NCBI chr17:34,138,452...34,148,264
Ensembl chr17:34,134,873...34,148,266
JBrowse link
G Tbk1 TANK-binding kinase 1 IAGP MGI PMID:18256672 NCBI chr10:121,382,360...121,422,699
Ensembl chr10:121,382,360...121,422,692
JBrowse link
G Tnf tumor necrosis factor IAGP MGI PMID:12486099 PMID:18256672 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tnfaip8l2 tumor necrosis factor, alpha-induced protein 8-like 2 IAGP MGI PMID:18455983 NCBI chr 3:95,046,832...95,051,581
Ensembl chr 3:95,046,832...95,049,671
JBrowse link
G Tnfrsf9 tumor necrosis factor receptor superfamily, member 9 IAGP MGI PMID:12023342 PMID:12752681 NCBI chr 4:151,004,612...151,030,561
Ensembl chr 4:150,999,019...151,030,559
JBrowse link
G Tnfsf14 tumor necrosis factor (ligand) superfamily, member 14 IAGP MGI PMID:11994431 PMID:12807825 NCBI chr17:57,496,437...57,501,182
Ensembl chr17:57,496,492...57,501,177
JBrowse link
G Tnfsf9 tumor necrosis factor (ligand) superfamily, member 9 IAGP MGI PMID:10528184 NCBI chr17:57,412,113...57,414,757
Ensembl chr17:57,412,325...57,414,757
JBrowse link
G Tpp2 tripeptidyl peptidase II IAGP MGI PMID:18362329 NCBI chr 1:43,973,130...44,042,160
Ensembl chr 1:43,972,807...44,042,160
JBrowse link
decreased cytotoxic T cell apoptosis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gzmb granzyme B IAGP MGI PMID:22801574 NCBI chr14:56,496,293...56,499,791
Ensembl chr14:56,496,295...56,499,717
JBrowse link
G Serpinb9 serine (or cysteine) peptidase inhibitor, clade B, member 9 IAGP MGI PMID:22801574 NCBI chr13:33,181,044...33,201,938
Ensembl chr13:33,187,233...33,201,940
JBrowse link
decreased cytotoxic T cell cytolysis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 1700016L21Rik RIKEN cDNA 1700016L21 gene IAGP MGI PMID:12196292 NCBI chr 1:80,423,649...80,453,377
Ensembl chr 1:80,405,912...80,457,752
JBrowse link
G Batf3 basic leucine zipper transcription factor, ATF-like 3 IAGP MGI PMID:19008445 NCBI chr 1:190,830,611...190,841,140
Ensembl chr 1:190,830,044...190,841,142
JBrowse link
G Cd226 CD226 antigen IAGP MGI PMID:19029379 PMID:19029380 NCBI chr18:89,195,078...89,290,356
Ensembl chr18:89,195,091...89,290,353
JBrowse link
G Cd28 CD28 antigen IAGP MGI PMID:15024044 NCBI chr 1:60,785,547...60,812,521
Ensembl chr 1:60,755,959...60,812,518
JBrowse link
G Cd3g CD3 antigen, gamma polypeptide IAGP MGI PMID:11160319 NCBI chr 9:44,880,870...44,891,729
Ensembl chr 9:44,880,870...44,891,729
JBrowse link
G Cd4 CD4 antigen IAGP MGI PMID:8500525 NCBI chr 6:124,841,656...124,865,210
Ensembl chr 6:124,841,655...124,865,184
JBrowse link
G Cd7 CD7 antigen IAGP MGI PMID:9637484 NCBI chr11:120,927,573...120,930,304
Ensembl chr11:120,927,573...120,930,244
JBrowse link
G Cd8a CD8 subunit alpha IAGP MGI PMID:8500525 NCBI chr 6:71,350,411...71,356,155
Ensembl chr 6:71,350,411...71,356,157
JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1, CNS IAGP MGI PMID:15913791 NCBI chr19:8,641,369...8,660,970
Ensembl chr19:8,641,153...8,660,951
JBrowse link
G Cimap2 ciliary microtubule associated protein 2 IAGP MGI PMID:25883318 NCBI chr 4:106,448,105...106,474,594
Ensembl chr 4:106,448,106...106,474,438
JBrowse link
G Elf4 E74 like ETS transcription factor 4 IAGP MGI PMID:12387738 NCBI chr  X:47,499,926...47,552,009
Ensembl chr  X:47,499,923...47,552,009
JBrowse link
G Fasl Fas ligand IAGP MGI PMID:7512035 PMID:19794494 NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064
JBrowse link
G Gzma granzyme A IAGP MGI PMID:9242702 NCBI chr13:113,230,358...113,237,515
Ensembl chr13:113,230,359...113,237,515
JBrowse link
G Gzmb granzyme B IAGP MGI PMID:8137431 PMID:15699143 NCBI chr14:56,496,293...56,499,791
Ensembl chr14:56,496,295...56,499,717
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 IAGP MGI PMID:12944494 NCBI chr  X:52,076,955...52,110,537
Ensembl chr  X:52,077,014...52,110,536
JBrowse link
G Il21r interleukin 21 receptor IAGP MGI PMID:11970879 PMID:15630141 NCBI chr 7:125,202,424...125,232,742
Ensembl chr 7:125,202,601...125,232,742
JBrowse link
G Il4 interleukin 4 IAGP MGI PMID:7609051 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496
JBrowse link
G Il6 interleukin 6 IAGP MGI PMID:8127368 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Impdh1 inosine monophosphate dehydrogenase 1 IAGP MGI PMID:12944494 NCBI chr 6:29,200,435...29,216,363
Ensembl chr 6:29,200,433...29,216,363
JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D IEA MGI NCBI chr 1:87,548,034...87,648,232
Ensembl chr 1:87,548,034...87,648,229
JBrowse link
G Itgal integrin alpha L IAGP MGI PMID:15955836 NCBI chr 7:126,895,404...126,934,309
Ensembl chr 7:126,895,432...126,934,310
JBrowse link
G Lyst lysosomal trafficking regulator IAGP MGI PMID:6977094 NCBI chr13:13,764,896...13,953,388
Ensembl chr13:13,764,982...13,953,388
JBrowse link
G Mavs mitochondrial antiviral signaling protein IAGP MGI PMID:18178804 NCBI chr 2:131,075,445...131,089,945
Ensembl chr 2:131,075,983...131,089,945
JBrowse link
G Mbtps1 membrane-bound transcription factor peptidase, site 1 IEA MGI NCBI chr 8:120,234,890...120,285,603
Ensembl chr 8:120,234,895...120,285,474
JBrowse link
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta IAGP MGI PMID:17723215 NCBI chr 4:149,733,625...149,787,023
Ensembl chr 4:149,733,625...149,787,028
JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma IAGP MGI PMID:17723215 NCBI chr12:32,223,128...32,258,675
Ensembl chr12:32,223,472...32,258,658
JBrowse link
G Pnliprp2 pancreatic lipase-related protein 2 IAGP MGI PMID:9813028 NCBI chr19:58,748,155...58,765,966
Ensembl chr19:58,748,151...58,765,966
JBrowse link
G Pnp purine-nucleoside phosphorylase IAGP MGI PMID:10859343 NCBI chr14:51,181,760...51,190,869
Ensembl chr14:51,168,539...51,190,869
JBrowse link
G Prf1 perforin 1 (pore forming protein) IAGP MGI PMID:7526382 PMID:7972104 PMID:8164737 PMID:23160464 NCBI chr10:61,133,530...61,140,463
Ensembl chr10:61,133,612...61,140,459
JBrowse link
G Prkcq protein kinase C, theta IAGP MGI PMID:15024044 NCBI chr 2:11,176,922...11,306,033
Ensembl chr 2:11,176,919...11,306,033
JBrowse link
G Psme2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) IAGP MGI PMID:10591649 NCBI chr14:55,824,897...55,828,558
Ensembl chr14:55,824,898...55,828,570
JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C IAGP MGI PMID:8334701 PMID:9725213 NCBI chr 1:137,990,601...138,103,491
Ensembl chr 1:137,990,599...138,103,446
JBrowse link
G Rab27a RAB27A, member RAS oncogene family IAGP MGI PMID:11266472 PMID:11266473 PMID:23160464 NCBI chr 9:72,952,092...73,004,905
Ensembl chr 9:72,952,136...73,004,911
JBrowse link
G Rabggta Rab geranylgeranyl transferase, a subunit IAGP MGI PMID:11266472 NCBI chr14:55,953,321...55,959,720
Ensembl chr14:55,952,873...55,959,720
JBrowse link
G Rel reticuloendotheliosis oncogene IAGP MGI PMID:10221648 NCBI chr11:23,686,847...23,720,969
Ensembl chr11:23,686,847...23,720,970
JBrowse link
G Serpinb9 serine (or cysteine) peptidase inhibitor, clade B, member 9 IAGP MGI PMID:16618603 NCBI chr13:33,181,044...33,201,938
Ensembl chr13:33,187,233...33,201,940
JBrowse link
G Sh2d1a SH2 domain containing 1A IAGP MGI PMID:22683123 NCBI chr  X:41,591,442...41,610,974
Ensembl chr  X:41,591,330...41,618,207
JBrowse link
G Stat1 signal transducer and activator of transcription 1 IEA MGI NCBI chr 1:52,158,588...52,201,024
Ensembl chr 1:52,158,599...52,201,024
JBrowse link
G Stx11 syntaxin 11 IAGP MGI PMID:23160464 NCBI chr10:12,813,961...12,840,242
Ensembl chr10:12,813,953...12,840,042
JBrowse link
G Tap1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) IAGP MGI PMID:10973281 NCBI chr17:34,406,530...34,416,199
Ensembl chr17:34,406,527...34,416,199
JBrowse link
G Tapbp TAP binding protein IAGP MGI PMID:10973281 NCBI chr17:34,138,452...34,148,264
Ensembl chr17:34,134,873...34,148,266
JBrowse link
G Tbk1 TANK-binding kinase 1 IAGP MGI PMID:18256672 NCBI chr10:121,382,360...121,422,699
Ensembl chr10:121,382,360...121,422,692
JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 IAGP MGI PMID:18178804 NCBI chr17:56,576,462...56,583,767
Ensembl chr17:56,576,319...56,583,786
JBrowse link
G Tnf tumor necrosis factor IAGP MGI PMID:18256672 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tnfsf14 tumor necrosis factor (ligand) superfamily, member 14 IAGP MGI PMID:11994431 PMID:12070288 NCBI chr17:57,496,437...57,501,182
Ensembl chr17:57,496,492...57,501,177
JBrowse link
G Tox thymocyte selection-associated high mobility group box IAGP MGI PMID:18195075 NCBI chr 4:6,686,353...6,991,557
Ensembl chr 4:6,686,353...6,991,557
JBrowse link
G Unc13d unc-13 homolog D IAGP MGI PMID:17420270 NCBI chr11:115,952,921...115,969,321
Ensembl chr11:115,952,921...115,968,787
JBrowse link
G Xcl1 chemokine (C motif) ligand 1 IAGP MGI PMID:19913446 NCBI chr 1:164,759,216...164,763,094
Ensembl chr 1:164,759,213...164,763,096
JBrowse link
increased cytotoxic T cell cytolysis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cimap2 ciliary microtubule associated protein 2 IAGP MGI PMID:25883318 NCBI chr 4:106,448,105...106,474,594
Ensembl chr 4:106,448,106...106,474,438
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16965
    immune system phenotype 5709
      abnormal immune system physiology 3489
        abnormal immune cell physiology 1824
          abnormal leukocyte physiology 1788
            abnormal lymphocyte physiology 1313
              abnormal T cell physiology 778
                abnormal CD8-positive, alpha-beta T cell physiology 128
                  abnormal cytotoxic T cell physiology + 89
paths to the root