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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal basement membrane morphology
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Accession:MP:0004272 term browser browse the term
Definition:anomaly in the structure, organization and/or placement of the extracellular supportive tissue adjacent to the basal surface of the epithelia, including the epithelium of muscle cells, fat cells and Schwann cells; it is comprised of type IV collagen, laminin, and sulfated proteoglycans and other components and consists of two layers, the basal lamina and the lamina reticularis
Comment:Note: Basal lamina and lamina reticularis (or of two basal laminae) compose the basement membrane. Thus, in strict sense, the term basement membrane is different from and should not be confused with basal lamina.
Synonyms:exact_synonym: abnormal basement lamina morphology
 narrow_synonym: basement membrane dysplasia

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  mammalian phenotype 0
    cellular phenotype 0
      abnormal extracellular matrix morphology 0
        abnormal basement membrane morphology 0
          abnormal basal lamina morphology 0
          abnormal cochlear basement membrane morphology 0
          impaired basement membrane formation 0
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