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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:tau protein deposits
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Accession:MP:0004250 term browser browse the term
Definition:formation of self-assembled tangles of paired helical filaments and straight filaments due to hyperphosphorylation of the tau protein; often seen in neuronal tissues of individuals with neurodegenerative disorders
Synonyms:exact_synonym: tau protein tangles



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tau protein deposits term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein IAGP MGI PMID:24278307 NCBI chr16:84,751,236...84,972,187
Ensembl chr16:84,746,573...84,970,654
JBrowse link
G Cav1 caveolin 1, caveolae protein IAGP MGI PMID:21203469 NCBI chr 6:17,306,387...17,341,323
Ensembl chr 6:17,306,334...17,341,451
JBrowse link
G Fgf14 fibroblast growth factor 14 IAGP MGI PMID:16291936 PMID:24503275 NCBI chr14:124,211,257...124,915,098
Ensembl chr14:124,215,319...124,914,539
JBrowse link
G Grn granulin IAGP MGI PMID:29382817 NCBI chr11:102,321,333...102,327,635
Ensembl chr11:102,321,141...102,327,874
JBrowse link
G Hspa4 heat shock protein 4 IAGP MGI PMID:20679486 NCBI chr11:53,150,641...53,191,306
Ensembl chr11:53,150,641...53,191,284
JBrowse link
G Il33 interleukin 33 IAGP MGI PMID:28675392 NCBI chr19:29,902,513...29,938,118
Ensembl chr19:29,902,514...29,938,118
JBrowse link
G Khdrbs2 KH domain containing, RNA binding, signal transduction associated 2 IAGP MGI PMID:19503083 NCBI chr 1:32,211,683...32,744,305
Ensembl chr 1:32,211,795...32,697,649
JBrowse link
G Klc1 kinesin light chain 1 IAGP MGI PMID:19420244 NCBI chr12:111,724,869...111,774,278
Ensembl chr12:111,725,283...111,774,278
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 IAGP MGI PMID:25836420 NCBI chr15:91,556,994...91,700,327
Ensembl chr15:91,557,378...91,700,323
JBrowse link
G Mapt microtubule-associated protein tau IAGP MGI PMID:12859672 NCBI chr11:104,120,235...104,222,916
Ensembl chr11:104,122,216...104,222,916
JBrowse link
G Nos2 nitric oxide synthase 2, inducible IAGP MGI PMID:18272675 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase IAGP MGI PMID:17623040 NCBI chr17:11,059,227...12,282,257
Ensembl chr17:11,059,271...12,282,248
JBrowse link
G Psen1 presenilin 1 IAGP MGI PMID:16377636 PMID:24278307 NCBI chr12:83,734,926...83,781,869
Ensembl chr12:83,734,926...83,781,973
JBrowse link
G Sorl1 sortilin-related receptor, LDLR class A repeats-containing IAGP MGI PMID:22986780 NCBI chr 9:41,876,005...42,035,593
Ensembl chr 9:41,876,016...42,035,593
JBrowse link
G Stub1 STIP1 homology and U-Box containing protein 1 IAGP MGI PMID:16111477 NCBI chr17:26,049,608...26,051,893
Ensembl chr17:26,049,479...26,052,378
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16725
    nervous system phenotype 4606
      abnormal nervous system morphology 3649
        nervous system inclusion bodies 94
          tau protein deposits 16
Path 2
Term Annotations click to browse term
  mammalian phenotype 16725
    nervous system phenotype 4606
      abnormal nervous system morphology 3649
        abnormal brain morphology 2117
          brain lesion 71
            tau protein deposits 16
paths to the root