Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:tau protein deposits
go back to main search page
Accession:MP:0004250 term browser browse the term
Definition:formation of self-assembled tangles of paired helical filaments and straight filaments due to hyperphosphorylation of the tau protein; often seen in neuronal tissues of individuals with neurodegenerative disorders
Synonyms:exact_synonym: tau protein tangles


show annotations for term's descendants           Sort by:
tau protein deposits term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
S BDIV-Myo5a/StcRrrc IAGP in brain stem, mesencephalon, olfactory bulb, frontal cortex; compared to control BD-IV RGD PMID:29217155 RGD:42721980
S SHR-Tg(Thy1-MAPT)318 IMP RGD PMID:16753151 RGD:2290296
S SHR-Tg(Thy1-MAPT)72 IMP RGD PMID:16753151 RGD:2290296
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5417
    nervous system phenotype 376
      abnormal nervous system morphology 214
        nervous system inclusion bodies 10
          tau protein deposits 3
Path 2
Term Annotations click to browse term
  mammalian phenotype 5417
    nervous system phenotype 376
      abnormal nervous system morphology 214
        abnormal brain morphology 139
          brain lesion 15
            tau protein deposits 3
paths to the root