MAMMALIAN PHENOTYPE - ANNOTATIONS
The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term: salt-sensitive hypertension
Accession: MP:0004217
browse the term
Definition: sustained high blood pressure that is maintained with a normal or increase in the amount of salt consumed in the diet; blood pressure may return to normotensive with a low salt diet
Synonyms: exact_synonym: salt-induced hypertension
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Alms1
ALMS1, centrosome and basal body associated protein
exacerbates
IMP
compared to wild type
RGD
PMID:30385718
RGD:151361229
NCBI chr 4:118,125,581...118,226,005
Ensembl chr 4:118,125,607...118,226,005
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Alms1em1Mcwi
Alstrom syndrome 1 homolog (human); zinc finger nuclease induced mutant 1, Medical College of Wisconsin
exacerbates
IMP
compared to wild type
RGD
PMID:30385718
RGD:151361229
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Astn1
astrotactin 1
IMP
RGD
PMID:24714719
RGD:12792227
NCBI chr13:70,537,423...70,855,440
Ensembl chr13:70,537,703...70,855,440
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Brinp2
BMP/retinoic acid inducible neural specific 2
IMP
RGD
PMID:24714719
RGD:12792227
NCBI chr13:70,431,006...70,532,766
Ensembl chr13:70,431,010...70,531,810
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Btg2
BTG anti-proliferation factor 2
IAGP
RGD
PMID:23817491
RGD:12802368
NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
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Cd247
Cd247 molecule
severity
IMP
RGD
PMID:24343121
RGD:13442481
NCBI chr13:78,043,302...78,118,437
Ensembl chr13:78,043,307...78,122,263
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Cd247em1Mcwi
Cd247 molecule; zinc finger nuclease induced mutant 1, Medical College of Wisconsin
severity
IMP
RGD
PMID:24343121
RGD:13442481
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Chi3l1
chitinase 3 like 1
IAGP
RGD
PMID:23460292
RGD:12802369
NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787
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Chit1
chitinase 1
IAGP
RGD
PMID:23460292
RGD:12802369
NCBI chr13:45,565,841...45,613,593
Ensembl chr13:45,593,845...45,613,592
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Cop1
COP1, E3 ubiquitin ligase
IMP
RGD
PMID:24714719
RGD:12792227
NCBI chr13:71,467,164...71,561,826
Ensembl chr13:71,429,961...71,538,890
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Etnk2
ethanolamine kinase 2
IAGP
RGD
PMID:23460292
RGD:12802369
NCBI chr13:44,811,012...44,829,052
Ensembl chr13:44,811,015...44,829,037
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Fmod
fibromodulin
IAGP
RGD
PMID:23817491
RGD:12802368
NCBI chr13:45,493,517...45,504,134
Ensembl chr13:45,493,517...45,504,133
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Gpr37l1
G protein-coupled receptor 37-like 1
IAGP
RGD
PMID:23460292
RGD:12802369
NCBI chr13:46,598,574...46,605,421
Ensembl chr13:46,598,578...46,605,421
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Hsd11b2
hydroxysteroid 11-beta dehydrogenase 2
IMP
RGD
PMID:26077568
RGD:13800514
NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899
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Hsd11b2em1Jmul
hydroxysteroid 11-beta dehydrogenase 2; ZFN induced mutant1, Jmul
IMP
RGD
PMID:26077568
RGD:13800514
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Ipo9
importin 9
IAGP
RGD
PMID:23460292
RGD:12802369
NCBI chr13:46,810,460...46,862,694
Ensembl chr13:46,813,171...46,862,673
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Kcnj1
potassium inwardly-rectifying channel, subfamily J, member 1
IMP
RGD
PMID:23753405
RGD:13782272
NCBI chr 8:30,779,883...30,808,607
Ensembl chr 8:30,753,617...30,813,796
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Kcnj1em1Kasu
potassium voltage-gated channel subfamily J member 1; ZFN induced mutant 1,Kasu
IMP
RGD
PMID:23753405
RGD:13782272
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Lgr6
leucine-rich repeat-containing G protein-coupled receptor 6
IAGP
RGD
PMID:23460292
RGD:12802369
NCBI chr13:46,424,382...46,544,074
Ensembl chr13:46,424,383...46,543,945
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Mgat5
alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase
IAGP
RGD
PMID:21257920
RGD:12798539
NCBI chr13:38,675,776...38,959,697
Ensembl chr13:38,676,119...38,959,513
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Mybph
myosin binding protein H
IAGP
RGD
PMID:23460292
RGD:12802369
NCBI chr13:45,653,156...45,660,893
Ensembl chr13:45,653,234...45,660,893
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Ncf2
neutrophil cytosolic factor 2
ameliorates
IMP
compared to wild-type littermates
RGD
PMID:22326221
RGD:9587793
NCBI chr13:64,955,622...64,986,144
Ensembl chr13:64,955,503...64,986,277
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Ncf2em1Mcwi
neutrophil cytosolic factor 2; zinc finger nuclease induced mutant 1,Mcwi
ameliorates
IMP
compared to wild-type littermates
RGD
PMID:22326221
RGD:9587793
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Nckap5
NCK-associated protein 5
IAGP
RGD
PMID:21257920
RGD:12798539
NCBI chr13:37,369,948...38,283,257
Ensembl chr13:37,370,792...38,283,268
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Nox4
NADPH oxidase 4
severity
IMP
RGD
PMID:26644237
RGD:11085830
NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406
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Optc
opticin
IAGP
RGD
PMID:23817491
RGD:12802368
NCBI chr13:45,353,954...45,368,254
Ensembl chr13:45,355,148...45,365,237
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Pappa2
pappalysin 2
IMP
RGD
PMID:24714719
RGD:12792227
NCBI chr13:70,873,918...71,147,874
Ensembl chr13:70,876,794...71,147,779
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Plekha6
pleckstrin homology domain containing A6
IAGP
RGD
PMID:23460292
RGD:12802369
NCBI chr13:44,614,740...44,754,951
Ensembl chr13:44,615,011...44,754,673
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Plekha7
pleckstrin homology domain containing A7
ameliorates
IMP
compared to wild type
RGD
PMID:25136115
RGD:11079199
NCBI chr 1:170,364,524...170,547,843
Ensembl chr 1:170,365,135...170,547,775
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Plekha7em4Mcwi
pleckstrin homology domain containing, family A member 7; zinc finger nuclease induced mutant 4, Medical College of Wisconsin
ameliorates
IMP
compared to wild type
RGD
PMID:25136115
RGD:11079199
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Prelp
proline and arginine rich end leucine rich repeat protein
IAGP
RGD
PMID:23817491
RGD:12802368
NCBI chr13:45,368,407...45,391,480
Ensembl chr13:45,370,533...45,380,270
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Psme2-ps1
proteasome activator subunit 2, pseudogene 1
IAGP
RGD
PMID:21257920
RGD:12798539
NCBI chr13:38,189,375...38,190,347
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Ptprv
protein tyrosine phosphatase, receptor type, V
IAGP
RGD
PMID:23460292
RGD:12802369
NCBI chr13:46,548,125...46,569,148
Ensembl chr13:46,548,128...46,568,329
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Ren
renin
IAGP
RGD
PMID:23817491
RGD:12802368
NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489
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Resp18
regulated endocrine-specific protein 18
IMP
RGD
PMID:29570433
RGD:14348960
NCBI chr 9:76,765,179...76,771,824
Ensembl chr 9:76,764,590...76,778,722
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Resp18em2Mcwi
regulated endocrine-specific protein 18; zinc finger nuclease induced mutant 2, Medical College of Wisconsin
IMP
RGD
PMID:29570433
RGD:14348960
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Rnpep
arginyl aminopeptidase
IAGP
RGD
PMID:23460292
RGD:12802369
NCBI chr13:46,699,458...46,717,829
Ensembl chr13:46,699,463...46,717,998
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Sox13
SRY-box transcription factor 13
IAGP
RGD
PMID:23460292
RGD:12802369
NCBI chr13:44,831,097...44,875,522
Ensembl chr13:44,831,085...44,875,762
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Syt2
synaptotagmin 2
IAGP
RGD
PMID:23460292
RGD:12802369
NCBI chr13:46,088,046...46,197,976
Ensembl chr13:46,185,282...46,193,859
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Tmem163
transmembrane protein 163
IAGP
RGD
PMID:21257920
RGD:12798539
NCBI chr13:38,967,913...39,141,664
Ensembl chr13:38,968,101...39,141,452
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Tnr
tenascin R
IMP
RGD
PMID:24714719
RGD:12792227
NCBI chr13:71,751,714...72,172,731
Ensembl chr13:72,091,585...72,167,641
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tuba1c-ps1
tubulin, alpha 1C, pseudogene 1
IAGP
RGD
PMID:21257920
RGD:12798539
NCBI chr13:38,507,496...38,508,836
Ensembl chr13:38,507,401...38,508,943 Ensembl chr13:38,507,401...38,508,943
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