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The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories ( For more information about these ontologies, see the MGI Publications Page at

Term:salt-sensitive hypertension
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Accession:MP:0004217 term browser browse the term
Definition:sustained high blood pressure that is maintained with a normal or increase in the amount of salt consumed in the diet; blood pressure may return to normotensive with a low salt diet
Synonyms:exact_synonym: salt-induced hypertension

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salt-sensitive hypertension term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alms1 ALMS1, centrosome and basal body associated protein exacerbates IMP compared to wild type RGD PMID:30385718 RGD:151361229 NCBI chr 4:118,125,581...118,226,005
Ensembl chr 4:118,125,607...118,226,005
JBrowse link
G Alms1em1Mcwi Alstrom syndrome 1 homolog (human); zinc finger nuclease induced mutant 1, Medical College of Wisconsin exacerbates IMP compared to wild type RGD PMID:30385718 RGD:151361229
G Astn1 astrotactin 1 IMP RGD PMID:24714719 RGD:12792227 NCBI chr13:70,537,423...70,855,440
Ensembl chr13:70,537,703...70,855,440
JBrowse link
G Brinp2 BMP/retinoic acid inducible neural specific 2 IMP RGD PMID:24714719 RGD:12792227 NCBI chr13:70,431,006...70,532,766
Ensembl chr13:70,431,010...70,531,810
JBrowse link
G Btg2 BTG anti-proliferation factor 2 IAGP RGD PMID:23817491 RGD:12802368 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
JBrowse link
G Cd247 Cd247 molecule severity IMP RGD PMID:24343121 RGD:13442481 NCBI chr13:78,043,302...78,118,437
Ensembl chr13:78,043,307...78,122,263
JBrowse link
G Cd247em1Mcwi Cd247 molecule; zinc finger nuclease induced mutant 1, Medical College of Wisconsin severity IMP RGD PMID:24343121 RGD:13442481
G Chi3l1 chitinase 3 like 1 IAGP RGD PMID:23460292 RGD:12802369 NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787
JBrowse link
G Chit1 chitinase 1 IAGP RGD PMID:23460292 RGD:12802369 NCBI chr13:45,565,841...45,613,593
Ensembl chr13:45,593,845...45,613,592
JBrowse link
G Cop1 COP1, E3 ubiquitin ligase IMP RGD PMID:24714719 RGD:12792227 NCBI chr13:71,467,164...71,561,826
Ensembl chr13:71,429,961...71,538,890
JBrowse link
G Etnk2 ethanolamine kinase 2 IAGP RGD PMID:23460292 RGD:12802369 NCBI chr13:44,811,012...44,829,052
Ensembl chr13:44,811,015...44,829,037
JBrowse link
G Fmod fibromodulin IAGP RGD PMID:23817491 RGD:12802368 NCBI chr13:45,493,517...45,504,134
Ensembl chr13:45,493,517...45,504,133
JBrowse link
G Gpr37l1 G protein-coupled receptor 37-like 1 IAGP RGD PMID:23460292 RGD:12802369 NCBI chr13:46,598,574...46,605,421
Ensembl chr13:46,598,578...46,605,421
JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 IMP RGD PMID:26077568 RGD:13800514 NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899
JBrowse link
G Hsd11b2em1Jmul hydroxysteroid 11-beta dehydrogenase 2; ZFN induced mutant1, Jmul IMP RGD PMID:26077568 RGD:13800514
G Ipo9 importin 9 IAGP RGD PMID:23460292 RGD:12802369 NCBI chr13:46,810,460...46,862,694
Ensembl chr13:46,813,171...46,862,673
JBrowse link
G Kcnj1 potassium inwardly-rectifying channel, subfamily J, member 1 IMP RGD PMID:23753405 RGD:13782272 NCBI chr 8:30,779,883...30,808,607
Ensembl chr 8:30,753,617...30,813,796
JBrowse link
G Kcnj1em1Kasu potassium voltage-gated channel subfamily J member 1; ZFN induced mutant 1,Kasu IMP RGD PMID:23753405 RGD:13782272
G Lgr6 leucine-rich repeat-containing G protein-coupled receptor 6 IAGP RGD PMID:23460292 RGD:12802369 NCBI chr13:46,424,382...46,544,074
Ensembl chr13:46,424,383...46,543,945
JBrowse link
G Mgat5 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase IAGP RGD PMID:21257920 RGD:12798539 NCBI chr13:38,675,776...38,959,697
Ensembl chr13:38,676,119...38,959,513
JBrowse link
G Mybph myosin binding protein H IAGP RGD PMID:23460292 RGD:12802369 NCBI chr13:45,653,156...45,660,893
Ensembl chr13:45,653,234...45,660,893
JBrowse link
G Nckap5 NCK-associated protein 5 IAGP RGD PMID:21257920 RGD:12798539 NCBI chr13:37,369,948...38,283,257
Ensembl chr13:37,370,792...38,283,268
JBrowse link
G Nox4 NADPH oxidase 4 severity IMP RGD PMID:26644237 RGD:11085830 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406
JBrowse link
G Optc opticin IAGP RGD PMID:23817491 RGD:12802368 NCBI chr13:45,353,954...45,368,254
Ensembl chr13:45,355,148...45,365,237
JBrowse link
G Pappa2 pappalysin 2 IMP RGD PMID:24714719 RGD:12792227 NCBI chr13:70,873,918...71,147,874
Ensembl chr13:70,876,794...71,147,779
JBrowse link
G Plekha6 pleckstrin homology domain containing A6 IAGP RGD PMID:23460292 RGD:12802369 NCBI chr13:44,614,740...44,754,951
Ensembl chr13:44,615,011...44,754,673
JBrowse link
G Plekha7 pleckstrin homology domain containing A7 ameliorates IMP compared to wild type RGD PMID:25136115 RGD:11079199 NCBI chr 1:170,364,524...170,547,843
Ensembl chr 1:170,365,135...170,547,775
JBrowse link
G Plekha7em4Mcwi pleckstrin homology domain containing, family A member 7; zinc finger nuclease induced mutant 4, Medical College of Wisconsin ameliorates IMP compared to wild type RGD PMID:25136115 RGD:11079199
G Prelp proline and arginine rich end leucine rich repeat protein IAGP RGD PMID:23817491 RGD:12802368 NCBI chr13:45,368,407...45,391,480
Ensembl chr13:45,370,533...45,380,270
JBrowse link
G Psme2-ps1 proteasome activator subunit 2, pseudogene 1 IAGP RGD PMID:21257920 RGD:12798539 NCBI chr13:38,189,375...38,190,347 JBrowse link
G Ptprv protein tyrosine phosphatase, receptor type, V IAGP RGD PMID:23460292 RGD:12802369 NCBI chr13:46,548,125...46,569,148
Ensembl chr13:46,548,128...46,568,329
JBrowse link
G Ren renin IAGP RGD PMID:23817491 RGD:12802368 NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489
JBrowse link
G Resp18 regulated endocrine-specific protein 18 IMP RGD PMID:29570433 RGD:14348960 NCBI chr 9:76,765,179...76,771,824
Ensembl chr 9:76,764,590...76,778,722
JBrowse link
G Resp18em2Mcwi regulated endocrine-specific protein 18; zinc finger nuclease induced mutant 2, Medical College of Wisconsin IMP RGD PMID:29570433 RGD:14348960
G Rnpep arginyl aminopeptidase IAGP RGD PMID:23460292 RGD:12802369 NCBI chr13:46,699,458...46,717,829
Ensembl chr13:46,699,463...46,717,998
JBrowse link
G Sox13 SRY-box transcription factor 13 IAGP RGD PMID:23460292 RGD:12802369 NCBI chr13:44,831,097...44,875,522
Ensembl chr13:44,831,085...44,875,762
JBrowse link
G Syt2 synaptotagmin 2 IAGP RGD PMID:23460292 RGD:12802369 NCBI chr13:46,088,046...46,197,976
Ensembl chr13:46,185,282...46,193,859
JBrowse link
G Tmem163 transmembrane protein 163 IAGP RGD PMID:21257920 RGD:12798539 NCBI chr13:38,967,913...39,141,664
Ensembl chr13:38,968,101...39,141,452
JBrowse link
G Tnr tenascin R IMP RGD PMID:24714719 RGD:12792227 NCBI chr13:71,751,714...72,172,731
Ensembl chr13:72,091,585...72,167,641
JBrowse link
G tuba1c-ps1 tubulin, alpha 1C, pseudogene 1 IAGP RGD PMID:21257920 RGD:12798539 NCBI chr13:38,507,496...38,508,836
Ensembl chr13:38,507,401...38,508,943
Ensembl chr13:38,507,401...38,508,943
JBrowse link

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  mammalian phenotype 5373
    cardiovascular system phenotype 1356
      abnormal cardiovascular system physiology 1132
        abnormal systemic arterial blood pressure 988
          increased systemic arterial blood pressure 629
            hypertension 174
              salt-sensitive hypertension 137
paths to the root