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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal noradrenaline level
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Accession:MP:0003964 term browser browse the term
Definition:aberrant amount of the hormone secreted by the adrenal medulla and acts as a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS; noradrenaline is the demethylated biosynthetic precursor of epinephrine
Synonyms:exact_synonym: abnormal adrenal noradrenaline level;   abnormal adrenal norepinephrine level;   abnormal norepinephrine level
 alt_id: MP:0003836


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abnormal noradrenaline level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase, copper transporting, alpha polypeptide IAGP MGI PMID:4858102 NCBI chr  X:105,070,830...105,171,766
Ensembl chr  X:105,070,882...105,168,532 		JBrowse link
G Ddc dopa decarboxylase IAGP MGI PMID:23275025 NCBI chr11:11,764,101...11,848,144
Ensembl chr11:11,764,101...11,848,144 		JBrowse link
G Ffar3 free fatty acid receptor 3 IAGP MGI PMID:21518883 NCBI chr 7:30,553,755...30,555,603
Ensembl chr 7:30,553,755...30,555,603 		JBrowse link
G Mrap2 melanocortin 2 receptor accessory protein 2 IAGP MGI PMID:23869016 NCBI chr 9:87,026,293...87,066,104
Ensembl chr 9:87,026,359...87,066,098 		JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 IAGP MGI PMID:17457314 NCBI chr 2:56,996,845...57,014,152
Ensembl chr 2:56,996,842...57,014,015 		JBrowse link
G Ntf3 neurotrophin 3 IAGP MGI PMID:11015591 NCBI chr 6:126,078,375...126,143,703
Ensembl chr 6:126,078,375...126,143,873 		JBrowse link
G Phox2b paired-like homeobox 2b IAGP MGI PMID:10360575 PMID:10736201 PMID:16319924 NCBI chr 5:67,251,751...67,256,399
Ensembl chr 5:67,251,742...67,256,644 		JBrowse link
G Psmc1 protease (prosome, macropain) 26S subunit, ATPase 1 IAGP MGI PMID:18701681 NCBI chr12:100,076,461...100,089,623
Ensembl chr12:100,076,413...100,089,664 		JBrowse link
G Slc18a2 solute carrier family 18 (vesicular monoamine), member 2 IAGP MGI PMID:9427250 PMID:11463816 PMID:19553450 NCBI chr19:59,249,310...59,284,444
Ensembl chr19:59,249,328...59,284,444 		JBrowse link
G Slc6a2 solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 IAGP MGI PMID:11124980 PMID:23580201 NCBI chr 8:93,687,100...93,728,295
Ensembl chr 8:93,686,707...93,728,295 		JBrowse link
G Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 IAGP MGI PMID:22131425 NCBI chr13:73,684,270...73,726,791
Ensembl chr13:73,684,866...73,726,791 		JBrowse link
G Slitrk1 SLIT and NTRK-like family, member 1 IAGP MGI PMID:18794888 NCBI chr14:109,147,420...109,151,671
Ensembl chr14:109,146,232...109,151,590 		JBrowse link
G Stat6 signal transducer and activator of transcription 6 IAGP MGI PMID:22101429 NCBI chr10:127,478,855...127,496,856
Ensembl chr10:127,478,855...127,496,826 		JBrowse link
G Taar1 trace amine-associated receptor 1 IAGP MGI PMID:17212650 NCBI chr10:23,796,304...23,797,302
Ensembl chr10:23,796,254...23,797,367 		JBrowse link
G Tacr1 tachykinin receptor 1 IAGP MGI PMID:9748515 NCBI chr 6:82,378,990...82,537,085
Ensembl chr 6:82,379,315...82,537,085 		JBrowse link
G Th tyrosine hydroxylase IAGP MGI PMID:7592982 PMID:10212311 PMID:10704516 PMID:18701681 NCBI chr 7:142,446,516...142,453,732
Ensembl chr 7:142,446,489...142,484,865 		JBrowse link
G Tyr tyrosinase IAGP MGI PMID:10212311 NCBI chr 7:87,073,979...87,142,637
Ensembl chr 7:87,073,979...87,142,720 		JBrowse link
G Ubr3 ubiquitin protein ligase E3 component n-recognin 3 IAGP MGI PMID:17462990 NCBI chr 2:69,727,276...69,854,354
Ensembl chr 2:69,727,590...69,854,357 		JBrowse link
abnormal circulating noradrenaline level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crh corticotropin releasing hormone IAGP MGI PMID:15033910 NCBI chr 3:19,747,565...19,749,560
Ensembl chr 3:19,747,565...19,749,560 		JBrowse link
absent circulating noradrenaline term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbh dopamine beta hydroxylase IAGP MGI PMID:7715704 NCBI chr 2:27,055,519...27,073,216
Ensembl chr 2:27,055,245...27,073,212 		JBrowse link
decreased circulating noradrenaline level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmal1 basic helix-loop-helix ARNT like 1 IAGP MGI PMID:17360665 NCBI chr 7:112,777,820...112,913,333
Ensembl chr 7:112,806,672...112,913,333 		JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 IAGP MGI PMID:18332118 NCBI chr12:54,225,767...54,250,660
Ensembl chr12:54,225,767...54,250,646 		JBrowse link
G Epas1 endothelial PAS domain protein 1 IAGP MGI PMID:9808618 NCBI chr17:87,061,292...87,140,838
Ensembl chr17:87,061,128...87,140,838 		JBrowse link
G Ffar3 free fatty acid receptor 3 IAGP MGI PMID:21518883 NCBI chr 7:30,553,755...30,555,603
Ensembl chr 7:30,553,755...30,555,603 		JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:18316029 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,055,336 		JBrowse link
G Itgb1 integrin beta 1 (fibronectin receptor beta) IAGP MGI PMID:16618804 NCBI chr 8:129,412,135...129,460,060
Ensembl chr 8:129,412,135...129,459,681 		JBrowse link
G Lepr leptin receptor IAGP MGI PMID:19103808 NCBI chr 4:101,574,393...101,676,375
Ensembl chr 4:101,574,601...101,672,549 		JBrowse link
G Npas2 neuronal PAS domain protein 2 IAGP MGI PMID:17360665 NCBI chr 1:39,233,013...39,402,321
Ensembl chr 1:39,232,812...39,402,317 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 IAGP MGI PMID:10357937 NCBI chr18:39,543,598...39,652,485
Ensembl chr18:39,543,598...39,652,474 		JBrowse link
decreased noradrenaline level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase, copper transporting, alpha polypeptide IAGP MGI PMID:4858102 PMID:25456742 NCBI chr  X:105,070,830...105,171,766
Ensembl chr  X:105,070,882...105,168,532 		JBrowse link
G Celf6 CUGBP, Elav-like family member 6 IAGP MGI PMID:23407934 NCBI chr 9:59,485,587...59,516,316
Ensembl chr 9:59,485,200...59,514,575 		JBrowse link
G Chga chromogranin A IAGP MGI PMID:16007257 NCBI chr12:102,521,200...102,531,286
Ensembl chr12:102,521,228...102,531,287 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 IAGP MGI PMID:22962254 NCBI chr 9:57,905,307...57,934,314
Ensembl chr 9:57,913,694...57,934,306 		JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 IAGP MGI PMID:9637684 NCBI chr10:128,403,392...128,425,504
Ensembl chr10:128,403,392...128,425,521 		JBrowse link
G Gch1 GTP cyclohydrolase 1 IAGP MGI PMID:30742839 NCBI chr14:47,391,352...47,426,870
Ensembl chr14:47,391,352...47,426,870 		JBrowse link
G Hint2 histidine triad nucleotide binding protein 2 IAGP MGI PMID:22961760 NCBI chr 4:43,654,227...43,656,445
Ensembl chr 4:43,654,227...43,656,466 		JBrowse link
G Il13 interleukin 13 IAGP MGI PMID:22101429 NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529 		JBrowse link
G Il4 interleukin 4 IAGP MGI PMID:22101429 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496 		JBrowse link
G Ly6e lymphocyte antigen 6 family member E IAGP MGI PMID:11784869 NCBI chr15:74,826,874...74,831,753
Ensembl chr15:74,826,900...74,831,752 		JBrowse link
G Mecp2 methyl CpG binding protein 2 IAGP MGI PMID:20633611 NCBI chr  X:73,070,198...73,129,296
Ensembl chr  X:73,070,198...73,129,296 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 IAGP MGI PMID:7628695 NCBI chr18:39,543,598...39,652,485
Ensembl chr18:39,543,598...39,652,474 		JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 IAGP MGI PMID:10506516 NCBI chr 2:56,996,845...57,014,152
Ensembl chr 2:56,996,842...57,014,015 		JBrowse link
G Pah phenylalanine hydroxylase IAGP MGI PMID:33790381 NCBI chr10:87,357,657...87,419,999
Ensembl chr10:87,357,657...87,419,998 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase IAGP MGI PMID:15249681 NCBI chr17:11,059,227...12,282,257
Ensembl chr17:11,059,271...12,282,248 		JBrowse link
G Pts 6-pyruvoyl-tetrahydropterin synthase IAGP MGI PMID:11517215 NCBI chr 9:50,432,917...50,440,017
Ensembl chr 9:50,432,917...50,440,024 		JBrowse link
G Rnf180 ring finger protein 180 IAGP MGI PMID:23926250 NCBI chr13:105,267,075...105,431,406
Ensembl chr13:105,266,509...105,431,323 		JBrowse link
G Rtl4 retrotransposon Gag like 4 IAGP MGI PMID:26402067 NCBI chr  X:143,471,147...143,905,410
Ensembl chr  X:143,471,903...143,905,407 		JBrowse link
G Spr sepiapterin reductase IAGP MGI PMID:16532389 PMID:18201550 NCBI chr 6:85,110,662...85,114,746
Ensembl chr 6:85,107,158...85,114,748 		JBrowse link
G Th tyrosine hydroxylase IAGP MGI PMID:12704806 NCBI chr 7:142,446,516...142,453,732
Ensembl chr 7:142,446,489...142,484,865 		JBrowse link
decreased urine noradrenaline level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gnas GNAS complex locus IAGP MGI PMID:10712433 NCBI chr 2:174,126,113...174,188,537
Ensembl chr 2:174,126,113...174,188,537 		JBrowse link
increased circulating noradrenaline level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 7630403G23Rik RIKEN cDNA 7630403G23 gene IAGP MGI PMID:19630976 NCBI chr 9:33,953,667...33,970,315
Ensembl chr 9:33,953,665...33,970,965 		JBrowse link
G A1cf APOBEC1 complementation factor IAGP MGI PMID:19328205 NCBI chr19:31,846,156...31,929,765
Ensembl chr19:31,846,164...31,926,395 		JBrowse link
G Acvrl1 activin A receptor, type II-like 1 IAGP MGI PMID:26398936 NCBI chr15:101,026,403...101,043,217
Ensembl chr15:101,026,403...101,043,217 		JBrowse link
G Aldh7a1 aldehyde dehydrogenase family 7, member A1 IAGP MGI PMID:32969477 NCBI chr18:56,657,794...56,706,112
Ensembl chr18:56,642,759...56,706,023 		JBrowse link
G Atp2a2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 IAGP MGI PMID:19328205 NCBI chr 5:122,591,576...122,640,288
Ensembl chr 5:122,591,576...122,640,288 		JBrowse link
G Braf Braf transforming gene IAGP MGI PMID:21383153 NCBI chr 6:39,580,171...39,702,592
Ensembl chr 6:39,580,171...39,702,397 		JBrowse link
G Chga chromogranin A IAGP MGI PMID:16007257 NCBI chr12:102,521,200...102,531,286
Ensembl chr12:102,521,228...102,531,287 		JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:19630976 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,055,336 		JBrowse link
G Kl klotho IAGP MGI PMID:15037532 NCBI chr 5:150,876,072...150,917,282
Ensembl chr 5:150,876,072...150,917,282 		JBrowse link
G Pdc phosducin IAGP MGI PMID:19959875 NCBI chr 1:150,195,168...150,209,657
Ensembl chr 1:150,195,168...150,209,657 		JBrowse link
G Rnls renalase, FAD-dependent amine oxidase IAGP MGI PMID:21178975 NCBI chr19:33,115,140...33,369,695
Ensembl chr19:33,115,147...33,369,665 		JBrowse link
G Slc6a2 solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 IAGP MGI PMID:23580201 NCBI chr 8:93,687,100...93,728,295
Ensembl chr 8:93,686,707...93,728,295 		JBrowse link
G Vav2 vav 2 oncogene IAGP MGI PMID:17202406 NCBI chr 2:27,152,116...27,317,620
Ensembl chr 2:27,152,116...27,317,045 		JBrowse link
G Vav3 vav 3 oncogene IAGP MGI PMID:16767097 PMID:17202406 NCBI chr 3:109,247,757...109,593,010
Ensembl chr 3:109,247,969...109,593,014 		JBrowse link
increased noradrenaline level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 7630403G23Rik RIKEN cDNA 7630403G23 gene IAGP MGI PMID:19630976 NCBI chr 9:33,953,667...33,970,315
Ensembl chr 9:33,953,665...33,970,965 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing IAGP MGI PMID:23684624 NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778 		JBrowse link
G Agrp agouti related neuropeptide IAGP MGI PMID:23864684 NCBI chr 8:106,293,327...106,306,477
Ensembl chr 8:106,293,330...106,364,025 		JBrowse link
G Agtr2 angiotensin II receptor, type 2 IAGP MGI PMID:12218346 NCBI chr  X:21,350,863...21,355,072
Ensembl chr  X:21,350,783...21,355,403 		JBrowse link
G Alkal2 ALK and LTK ligand 2 IAGP MGI PMID:35412887 NCBI chr12:30,934,323...30,943,855
Ensembl chr12:30,934,321...30,943,853 		JBrowse link
G Arhgef10 Rho guanine nucleotide exchange factor 10 IAGP MGI PMID:29456827 NCBI chr 8:14,956,405...15,051,085
Ensembl chr 8:14,961,663...15,051,085 		JBrowse link
G C2cd5 C2 calcium-dependent domain containing 5 IAGP MGI PMID:29378832 NCBI chr 6:142,956,646...143,045,878
Ensembl chr 6:142,956,646...143,045,867 		JBrowse link
G Cacna1a calcium channel, voltage-dependent, P/Q type, alpha 1A subunit IAGP MGI PMID:6123371 NCBI chr 8:85,065,257...85,366,880
Ensembl chr 8:85,065,268...85,366,875 		JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:19630976 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,055,336 		JBrowse link
G Htr1a 5-hydroxytryptamine (serotonin) receptor 1A IAGP MGI PMID:11080193 NCBI chr13:105,580,040...105,584,630
Ensembl chr13:105,580,147...105,584,630 		JBrowse link
G Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 IAGP MGI PMID:6123371 NCBI chr16:94,545,839...94,798,719
Ensembl chr16:94,549,495...94,798,560 		JBrowse link
G Lrtm2 leucine-rich repeats and transmembrane domains 2 IAGP MGI PMID:35615067 NCBI chr 6:119,292,094...119,315,009
Ensembl chr 6:119,292,094...119,307,727 		JBrowse link
G Maoa monoamine oxidase A IAGP MGI PMID:7792602 PMID:15272015 NCBI chr  X:16,485,937...16,554,051
Ensembl chr  X:16,485,937...16,554,057 		JBrowse link
G Maob monoamine oxidase B IAGP MGI PMID:15272015 NCBI chr  X:16,575,520...16,683,605
Ensembl chr  X:16,575,521...16,683,605 		JBrowse link
G Pnmt phenylethanolamine-N-methyltransferase IAGP MGI PMID:15517585 PMID:17698731 NCBI chr11:98,277,449...98,279,006
Ensembl chr11:98,277,276...98,279,007 		JBrowse link
G Rora RAR-related orphan receptor alpha IAGP MGI PMID:6123371 NCBI chr 9:68,560,627...69,295,528
Ensembl chr 9:68,561,068...69,295,528 		JBrowse link
G Sgce sarcoglycan, epsilon IAGP MGI PMID:27890709 NCBI chr 6:4,674,350...4,747,180
Ensembl chr 6:4,674,350...4,747,207 		JBrowse link
G Tafa1 TAFA chemokine like family member 1 IAGP MGI PMID:31689372 NCBI chr 6:96,090,135...96,634,169
Ensembl chr 6:96,090,135...96,634,159 		JBrowse link
G Vgf VGF nerve growth factor inducible IAGP MGI PMID:24497580 NCBI chr 5:137,054,156...137,062,205
Ensembl chr 5:137,055,246...137,062,205 		JBrowse link
increased urine noradrenaline level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gnas GNAS complex locus IAGP MGI PMID:10712433 NCBI chr 2:174,126,113...174,188,537
Ensembl chr 2:174,126,113...174,188,537 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 17088
    homeostasis/metabolism phenotype 7927
      abnormal homeostasis 7061
        abnormal catecholamine level 175
          abnormal noradrenaline level 73
            abnormal circulating noradrenaline level + 24
            decreased noradrenaline level + 29
            increased noradrenaline level + 32
paths to the root