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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:increased susceptibility to induced arthritis
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Accession:MP:0003724 term browser browse the term
Definition:more likely to be stricken with changes in the synovial membranes and thickening of articular structures, widespread degeneration of the collagen fibers in connective tissues, and by atrophy and rarefaction of bony structures that are induced by inflammatory responses caused by chemical or mechanical agents
Synonyms:exact_synonym: decreased resistance to induced arthritis



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increased susceptibility to induced arthritis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ncf1 neutrophil cytosolic factor 1 IAGP RGD PMID:12461526 RGD:628543 NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646
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Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5292
    skeleton phenotype 424
      abnormal skeleton physiology 183
        abnormal joint physiology 103
          joint inflammation 101
            arthritis 47
              increased susceptibility to induced arthritis 27
Path 2
Term Annotations click to browse term
  mammalian phenotype 5292
    immune system phenotype 485
      abnormal immune system physiology 373
        abnormal immune tolerance 117
          abnormal self tolerance 117
            autoimmune response 117
              abnormal susceptibility to autoimmune disorder 106
                increased susceptibility to autoimmune disorder 47
                  increased susceptibility to induced arthritis 27
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