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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal female reproductive system physiology
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Accession:MP:0003699 term browser browse the term
Definition:any functional anomaly of the female organs associated with producing offspring



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abnormal estrous cycle term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Egfr epidermal growth factor receptor IDA RGD PMID:11796513 RGD:70386 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Inha inhibin subunit alpha IDA rat transgene introduced into female mice RGD PMID:15359127 RGD:2290396 NCBI chr 9:76,994,465...76,997,366
Ensembl chr 9:76,993,589...76,997,248
JBrowse link
abnormal proestrus term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr2 estrogen receptor 2 IMP RGD PMID:28520870 RGD:38548924 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Esr2em1Soar estrogen receptor 2; ZFN induced mutant 1, Soar IMP RGD PMID:28520870 RGD:38548924
abnormal uterine spiral artery remodeling term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mmp12 matrix metallopeptidase 12 IMP RGD PMID:27807143 RGD:12910498 NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611
JBrowse link
anovulation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr2 estrogen receptor 2 IMP compared to wild type RGD PMID:29580824 PMID:28520870 RGD:38548925, RGD:38548924 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Esr2em1Soar estrogen receptor 2; ZFN induced mutant 1, Soar IMP compared to wild type RGD PMID:29580824 PMID:28520870 RGD:38548925, RGD:38548924
failure of embryo implantation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ndufc2 NADH:ubiquinone oxidoreductase subunit C2 IMP DNA:deletion:exon1:no homozygous knockout embryos found at implantation stage RGD PMID:26888427 RGD:11040458 NCBI chr 1:151,711,965...151,718,188
Ensembl chr 1:151,711,901...151,718,189
JBrowse link
G Ndufc2em1Mcwi NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2; zinc finger nuclease induced mutant 1, Medical College of Wisconsin IMP DNA:deletion:exon 1:no homozygous knockout embryos found at implantation stage RGD PMID:26888427 RGD:11040458
G Ndufc2em2Mcwi NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2; zinc finger nuclease induced mutant 2, Medical College of Wisconsin IMP DNA:deletion:exon 1:no homozygous knockout embryos found at implantation stage RGD PMID:26888427 RGD:11040458
female infertility term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr2 estrogen receptor 2 IMP RGD PMID:29580824 RGD:38548925 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Esr2em1Soar estrogen receptor 2; ZFN induced mutant 1, Soar IMP RGD PMID:29580824 RGD:38548925

Term paths to the root
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  mammalian phenotype 5400
    reproductive system phenotype 129
      abnormal reproductive system physiology 64
        abnormal female reproductive system physiology 12
          abnormal female germ cell physiology + 0
          abnormal gestational length + 0
          abnormal ovary physiology + 0
          abnormal oviduct physiology + 0
          abnormal ovulation + 4
          abnormal ovulation cycle + 6
          abnormal pregnancy + 6
          abnormal uterus physiology + 1
          abnormal vagina physiology + 0
          female infertility 4
          reduced female fertility 0
paths to the root