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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:decreased susceptibility to induced arthritis
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Accession:MP:0003436 term browser browse the term
Definition:less likely to be stricken with changes in the synovial membranes and thickening of articular structures, widespread degeneration of the collagen fibers in connective tissues, and by atrophy and rarefaction of bony structures that are induced by inflammatory responses caused by chemical or mechanical agents
Synonyms:exact_synonym: increased resistance to induced arthritis


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decreased susceptibility to induced arthritis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acan aggrecan IAGP MGI PMID:17510707 NCBI chr 7:79,053,226...79,115,099
Ensembl chr 7:79,053,483...79,115,099
JBrowse link
G Adam8 a disintegrin and metallopeptidase domain 8 IAGP MGI PMID:19737139 NCBI chr 7:139,978,932...139,995,207
Ensembl chr 7:139,978,932...139,992,562
JBrowse link
G Adamts5 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2) IAGP MGI PMID:15800624, PMID:20036347 NCBI chr16:85,858,157...85,901,125
Ensembl chr16:85,856,173...85,901,828
JBrowse link
G Aif1 allograft inflammatory factor 1 IAGP MGI PMID:23929822 NCBI chr17:35,170,986...35,176,083
Ensembl chr17:35,170,991...35,176,068
JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein IAGP MGI PMID:9091585 NCBI chr 5:149,265,004...149,288,153
Ensembl chr 5:149,264,767...149,288,153
JBrowse link
G Bmx BMX non-receptor tyrosine kinase IAGP MGI PMID:21471444 NCBI chr  X:164,192,842...164,258,193
Ensembl chr  X:164,192,842...164,258,193
JBrowse link
G C3 complement component 3 IAGP MGI PMID:15048732 NCBI chr17:57,203,967...57,228,136
Ensembl chr17:57,203,970...57,228,136
JBrowse link
G Cd1d1 CD1d1 antigen IAGP MGI PMID:15958069 NCBI chr 3:86,995,834...87,012,358
Ensembl chr 3:86,995,834...86,999,441
JBrowse link
G Cd276 CD276 antigen IAGP MGI PMID:26065426 NCBI chr 9:58,524,300...58,555,033
Ensembl chr 9:58,524,298...58,555,437
JBrowse link
G Cd44 CD44 antigen IAGP MGI PMID:11762953 NCBI chr 2:102,811,141...102,901,669
Ensembl chr 2:102,811,141...102,901,665
JBrowse link
G Cd69 CD69 antigen IAGP MGI PMID:12882836 NCBI chr 6:129,267,324...129,275,375
Ensembl chr 6:129,267,325...129,275,436
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) IAGP MGI PMID:16651620 NCBI chr17:29,090,979...29,100,722
Ensembl chr17:29,090,976...29,100,727
JBrowse link
G Cfb complement factor B IAGP MGI PMID:15048732 NCBI chr17:34,856,374...34,862,514
Ensembl chr17:34,856,374...34,862,518
JBrowse link
G Cfp complement factor properdin IAGP MGI PMID:20941861 NCBI chr  X:20,925,454...20,931,555
Ensembl chr  X:20,925,454...20,931,555
JBrowse link
G Clec5a C-type lectin domain family 5, member a IAGP MGI PMID:20212065 NCBI chr 6:40,574,898...40,585,805
Ensembl chr 6:40,574,894...40,585,821
JBrowse link
G Ctss cathepsin S IAGP MGI PMID:10072073 NCBI chr 3:95,526,786...95,556,405
Ensembl chr 3:95,526,786...95,556,403
JBrowse link
G Cxcr2 chemokine (C-X-C motif) receptor 2 IAGP MGI PMID:19109198 NCBI chr 1:74,153,994...74,161,246
Ensembl chr 1:74,153,989...74,161,246
JBrowse link
G Cxcr4 chemokine (C-X-C motif) receptor 4 IAGP MGI PMID:20939892 NCBI chr 1:128,588,199...128,592,299
Ensembl chr 1:128,588,199...128,592,293
JBrowse link
G Dgkz diacylglycerol kinase zeta IAGP MGI PMID:31801815 NCBI chr 2:91,932,822...91,976,443
Ensembl chr 2:91,932,824...91,975,864
JBrowse link
G Dusp2 dual specificity phosphatase 2 IAGP MGI PMID:16474395 NCBI chr 2:127,336,159...127,338,377
Ensembl chr 2:127,336,159...127,338,376
JBrowse link
G F2 coagulation factor II IAGP MGI PMID:21436072 NCBI chr 2:91,612,397...91,636,457
Ensembl chr 2:91,625,320...91,636,414
JBrowse link
G F2rl1 coagulation factor II (thrombin) receptor-like 1 IAGP MGI PMID:12511586 NCBI chr13:95,511,718...95,525,240
Ensembl chr13:95,511,732...95,525,227
JBrowse link
G Fcgr1 Fc receptor, IgG, high affinity I IAGP MGI PMID:11911824 NCBI chr 3:96,282,909...96,293,969
Ensembl chr 3:96,282,909...96,293,969
JBrowse link
G Fcgr3 Fc receptor, IgG, low affinity III IAGP MGI PMID:12528127 NCBI chr 1:171,051,169...171,065,915
Ensembl chr 1:171,051,174...171,064,935
JBrowse link
G Fcgr4 Fc receptor, IgG, low affinity IV IAGP MGI PMID:20974962 NCBI chr 1:171,018,926...171,029,761
Ensembl chr 1:171,018,920...171,029,761
JBrowse link
G Gpsm3 G-protein signalling modulator 3 (AGS3-like, C. elegans) IAGP MGI PMID:23280397 NCBI chr17:34,589,806...34,591,754
Ensembl chr17:34,589,806...34,591,754
JBrowse link
G Hc hemolytic complement IAGP MGI PMID:9485083 NCBI chr 2:34,983,329...35,068,506
Ensembl chr 2:34,983,331...35,061,438
JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit IAGP MGI PMID:12628185 NCBI chr12:73,901,324...73,947,554
Ensembl chr12:73,901,375...73,947,530
JBrowse link
G Il17a interleukin 17A IAGP MGI PMID:12721360 NCBI chr 1:20,730,905...20,734,496
Ensembl chr 1:20,730,905...20,734,496
JBrowse link
G Il1r1 interleukin 1 receptor, type I IAGP MGI PMID:12133972 NCBI chr 1:40,222,480...40,316,201
Ensembl chr 1:40,225,080...40,317,257
JBrowse link
G Il1rn interleukin 1 receptor antagonist IAGP MGI PMID:12721360 NCBI chr 2:24,336,860...24,351,491
Ensembl chr 2:24,336,853...24,351,494
JBrowse link
G Il6 interleukin 6 IAGP MGI PMID:24012418 NCBI chr 5:30,013,114...30,019,975
Ensembl chr 5:30,013,114...30,019,981
JBrowse link
G Irf1 interferon regulatory factor 1 IAGP MGI PMID:9317154 NCBI chr11:53,770,014...53,778,374
Ensembl chr11:53,770,014...53,778,374
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase IAGP MGI PMID:22101159 NCBI chr 5:75,574,987...75,656,722
Ensembl chr 5:75,574,916...75,656,722
JBrowse link
G Ksr1 kinase suppressor of ras 1 IAGP MGI PMID:17056543 NCBI chr11:79,013,440...79,146,533
Ensembl chr11:79,013,440...79,146,407
JBrowse link
G Lta lymphotoxin A IAGP MGI PMID:9834074 NCBI chr17:35,203,165...35,205,578
Ensembl chr17:35,203,165...35,205,351
JBrowse link
G Ltb4r1 leukotriene B4 receptor 1 IAGP MGI PMID:16670336, PMID:20656922 NCBI chr14:55,765,962...55,768,492
Ensembl chr14:55,765,962...55,768,494
JBrowse link
G Ltb4r2 leukotriene B4 receptor 2 IAGP MGI PMID:20656922 NCBI chr14:55,757,922...55,764,066
Ensembl chr14:55,761,428...55,765,138
JBrowse link
G Lyz2 lysozyme 2 IAGP MGI PMID:12628185, PMID:20941861 NCBI chr10:117,277,541...117,282,272
Ensembl chr10:117,277,331...117,282,321
JBrowse link
G Mapk11 mitogen-activated protein kinase 11 IEA MGI NCBI chr15:89,142,482...89,149,606
Ensembl chr15:89,142,486...89,149,628
JBrowse link
G Mapk14 mitogen-activated protein kinase 14 IEA MGI NCBI chr17:28,691,342...28,748,405
Ensembl chr17:28,691,329...28,748,406
JBrowse link
G Mmp9 matrix metallopeptidase 9 IAGP MGI PMID:19364840 NCBI chr 2:164,940,326...164,955,850
Ensembl chr 2:164,940,780...164,955,850
JBrowse link
G Myd88 myeloid differentiation primary response gene 88 IAGP MGI PMID:19218085 NCBI chr 9:119,335,934...119,340,018
Ensembl chr 9:119,335,934...119,341,411
JBrowse link
G Ndst2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 IAGP MGI PMID:19109198 NCBI chr14:20,723,730...20,734,570
Ensembl chr14:20,723,730...20,734,562
JBrowse link
G Nfkbib nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta IAGP MGI PMID:20740013 NCBI chr 7:28,758,251...28,766,644
Ensembl chr 7:28,758,251...28,767,512
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 IAGP MGI PMID:19218085 NCBI chr 8:88,647,315...88,688,474
Ensembl chr 8:88,647,315...88,688,474
JBrowse link
G Panx3 pannexin 3 IAGP MGI PMID:26138248 NCBI chr 9:37,659,902...37,669,222
Ensembl chr 9:37,659,902...37,669,235
JBrowse link
G Pglyrp1 peptidoglycan recognition protein 1 IAGP MGI PMID:19218085 NCBI chr 7:18,884,690...18,890,438
Ensembl chr 7:18,871,331...18,890,459
JBrowse link
G Pglyrp2 peptidoglycan recognition protein 2 IAGP MGI PMID:19218085 NCBI chr17:32,412,459...32,424,219
Ensembl chr17:32,412,459...32,424,167
JBrowse link
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta IAGP MGI PMID:18412166 NCBI chr 4:149,649,168...149,702,566
Ensembl chr 4:149,649,168...149,702,571
JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma IAGP MGI PMID:18412166 NCBI chr12:32,173,397...32,208,677
Ensembl chr12:32,173,473...32,208,659
JBrowse link
G Plau plasminogen activator, urokinase IAGP MGI PMID:11891190 NCBI chr14:20,836,662...20,843,388
Ensembl chr14:20,836,660...20,843,385
JBrowse link
G Plcg2 phospholipase C, gamma 2 IAGP MGI PMID:20111715 NCBI chr 8:117,498,275...117,635,142
Ensembl chr 8:117,498,291...117,635,142
JBrowse link
G Ptger4 prostaglandin E receptor 4 (subtype EP4) IAGP MGI PMID:12208866 NCBI chr15:5,233,399...5,244,187
Ensembl chr15:5,206,661...5,244,187
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 IAGP MGI PMID:16556900 NCBI chr 2:36,216,742...36,258,593
Ensembl chr 2:36,230,426...36,252,272
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IAGP MGI PMID:16556900 NCBI chr 1:150,100,031...150,108,234
Ensembl chr 1:150,100,031...150,108,227
JBrowse link
G Rasgrp4 RAS guanyl releasing protein 4 IAGP MGI PMID:22511759 NCBI chr 7:29,134,607...29,153,961
Ensembl chr 7:29,134,851...29,153,961
JBrowse link
G Syvn1 synovial apoptosis inhibitor 1, synoviolin IAGP MGI PMID:12975321 NCBI chr19:6,046,576...6,053,718
Ensembl chr19:6,046,576...6,053,712
JBrowse link
G Tlr4 toll-like receptor 4 IAGP MGI PMID:19218085 NCBI chr 4:66,827,551...66,846,581
Ensembl chr 4:66,827,584...66,930,284
JBrowse link
G Tnf tumor necrosis factor IAGP MGI PMID:9834074 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a IAGP MGI PMID:12133972 NCBI chr 6:125,349,723...125,362,483
Ensembl chr 6:125,349,362...125,362,484
JBrowse link
G Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b IAGP MGI PMID:12133972 NCBI chr 4:145,212,368...145,246,870
Ensembl chr 4:145,213,463...145,246,870
JBrowse link
G Tnfsf13 tumor necrosis factor (ligand) superfamily, member 13 IAGP MGI PMID:19016524 NCBI chr11:69,682,577...69,685,554
Ensembl chr11:69,682,846...69,685,784
JBrowse link
G Tnfsf15 tumor necrosis factor (ligand) superfamily, member 15 IAGP MGI PMID:24140642 NCBI chr 4:63,724,600...63,745,059
Ensembl chr 4:63,727,084...63,745,113
Ensembl chr 4:63,727,084...63,745,113
JBrowse link
G Tpsab1 tryptase alpha/beta 1 IAGP MGI PMID:19109198 NCBI chr17:25,343,245...25,345,562
Ensembl chr17:25,343,245...25,345,562
JBrowse link
G Tpsb2 tryptase beta 2 IAGP MGI PMID:19109198 NCBI chr17:25,366,308...25,368,096
Ensembl chr17:25,366,305...25,369,098
JBrowse link
G Tyk2 tyrosine kinase 2 IAGP MGI PMID:11313413 NCBI chr 9:21,104,068...21,131,393
Ensembl chr 9:21,104,068...21,131,243
JBrowse link
G Tyrobp TYRO protein tyrosine kinase binding protein IAGP MGI PMID:20212065 NCBI chr 7:30,413,782...30,417,582
Ensembl chr 7:30,413,760...30,417,585
JBrowse link
G Zap70 zeta-chain (TCR) associated protein kinase IAGP MGI PMID:19841086 NCBI chr 1:36,761,798...36,782,821
Ensembl chr 1:36,761,798...36,782,818
JBrowse link
G Zfp36 zinc finger protein 36 IAGP MGI PMID:26831084 NCBI chr 7:28,376,784...28,379,228
Ensembl chr 7:28,376,784...28,380,253
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 14897
    skeleton phenotype 2945
      abnormal skeleton physiology 1046
        joint inflammation 204
          arthritis 192
            decreased susceptibility to induced arthritis 84
Path 2
Term Annotations click to browse term
  mammalian phenotype 14897
    immune system phenotype 4552
      abnormal immune system physiology 3153
        abnormal immune tolerance 636
          abnormal self tolerance 623
            autoimmune response 621
              altered susceptibility to autoimmune disorder 474
                decreased susceptibility to autoimmune disorder 244
                  decreased susceptibility to induced arthritis 84
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.