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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:decreased susceptibility to induced arthritis
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Accession:MP:0003436 term browser browse the term
Definition:less likely to be stricken with changes in the synovial membranes and thickening of articular structures, widespread degeneration of the collagen fibers in connective tissues, and by atrophy and rarefaction of bony structures that are induced by inflammatory responses caused by chemical or mechanical agents
Synonyms:exact_synonym: increased resistance to induced arthritis


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decreased susceptibility to induced arthritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
S DA.ACI-(D12Wox12-D12Rat53)/Arb induced IAGP compared to DA/Hsd RGD PMID:17329308 RGD:1600250 NCBI chr12:22,650,721...48,598,906 JBrowse link
S DA.ACI-(D2Mit12-D2Mgh29)/Nsi IDA RGD PMID:15641042 RGD:1358860 NCBI chr 2:181,990,297...235,290,110 JBrowse link
S DA.E3-(D12Got46-D12Rat26)/Rhd severity IDA
IAGP
compared to inducible strain DA/ZtmRhd RGD PMID:17490473, PMID:12817024 RGD:1625013, RGD:631850 NCBI chr12:25,307,118...29,014,362 JBrowse link
S DA.E3-(D4Mit16-D4Mgh11)/Rhd induced
severity
IAGP compared to treated DA/ZtmRhd
compared to inducible strain DA/ZtmRhd
RGD PMID:12817024, PMID:12817024 RGD:631850, RGD:631850 NCBI chr 4:127,777,294...168,047,091 JBrowse link
S DXE3/Ztm resistance IAGP compared to induced strain DA/Ztm RGD PMID:11090241 RGD:629570
S E3/ZtmRhd IDA pristane induced RGD PMID:14674011 RGD:2302026
S PVG.1AV1/Kini penetrance IAGP compared to DA/ZtmKini RGD PMID:12571866 RGD:629560

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5006
    skeleton phenotype 383
      abnormal skeleton physiology 161
        joint inflammation 95
          arthritis 45
            decreased susceptibility to induced arthritis 7
Path 2
Term Annotations click to browse term
  mammalian phenotype 5006
    immune system phenotype 428
      abnormal immune system physiology 345
        abnormal immune tolerance 116
          abnormal self tolerance 116
            autoimmune response 116
              altered susceptibility to autoimmune disorder 105
                decreased susceptibility to autoimmune disorder 59
                  decreased susceptibility to induced arthritis 7
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.