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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:increased cardiomyocyte apoptosis
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Accession:MP:0003222 term browser browse the term
Definition:increase in the number of cardiac muscle cells undergoing programmed cell death


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increased cardiomyocyte apoptosis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A1cf APOBEC1 complementation factor IAGP MGI PMID:19850880 PMID:20644257 PMID:24812305 PMID:27548259 NCBI chr19:31,846,156...31,929,765
Ensembl chr19:31,846,164...31,926,395 		JBrowse link
G Actc1 actin, alpha, cardiac muscle 1 IAGP MGI PMID:14605248 NCBI chr 2:113,877,763...113,883,356
Ensembl chr 2:113,877,763...113,884,029 		JBrowse link
G Adm adrenomedullin IAGP MGI PMID:16537897 NCBI chr 7:110,226,864...110,229,027
Ensembl chr 7:110,226,868...110,229,027 		JBrowse link
G Aifm1 apoptosis-inducing factor, mitochondrion-associated 1 IAGP MGI PMID:15933268 NCBI chr  X:47,563,821...47,602,440
Ensembl chr  X:47,563,821...47,602,440 		JBrowse link
G Akap6 A kinase anchor protein 6 IAGP MGI PMID:24812305 NCBI chr12:52,745,371...53,202,351
Ensembl chr12:52,746,166...53,202,382 		JBrowse link
G Bag3 BCL2-associated athanogene 3 IAGP MGI PMID:16936253 NCBI chr 7:128,125,307...128,148,705
Ensembl chr 7:128,125,340...128,148,705 		JBrowse link
G Bnip3l BCL2/adenovirus E1B interacting protein 3-like IAGP MGI PMID:18178777 NCBI chr14:67,222,688...67,246,580
Ensembl chr14:67,222,688...67,246,326 		JBrowse link
G Calcrl calcitonin receptor-like IAGP MGI PMID:16537897 NCBI chr 2:84,160,970...84,255,786
Ensembl chr 2:84,160,970...84,255,755 		JBrowse link
G Calr calreticulin IAGP MGI PMID:10739657 NCBI chr 8:85,568,717...85,573,560
Ensembl chr 8:85,568,479...85,573,563 		JBrowse link
G Casp3 caspase 3 IAGP MGI PMID:22949508 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724 		JBrowse link
G Casp8 caspase 8 IAGP MGI PMID:12404118 PMID:16245150 NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662 		JBrowse link
G Chd7 chromodomain helicase DNA binding protein 7 IAGP MGI PMID:24293546 NCBI chr 4:8,690,345...8,868,449
Ensembl chr 4:8,690,406...8,867,659 		JBrowse link
G Creg1 cellular repressor of E1A-stimulated genes 1 IAGP MGI PMID:27840305 NCBI chr 1:165,591,327...165,602,878
Ensembl chr 1:165,591,315...165,602,877 		JBrowse link
G Cxadr coxsackie virus and adenovirus receptor IAGP MGI PMID:15864812 NCBI chr16:78,098,114...78,156,673
Ensembl chr16:78,098,377...78,156,662 		JBrowse link
G Dicer1 dicer 1, ribonuclease type III IAGP MGI PMID:18256189 NCBI chr12:104,654,001...104,718,331
Ensembl chr12:104,654,001...104,718,211 		JBrowse link
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 IAGP MGI PMID:16327803 NCBI chr16:4,501,934...4,525,559
Ensembl chr16:4,457,853...4,525,559 		JBrowse link
G Dot1l DOT1 like histone lysine methyltransferase IAGP MGI PMID:21289070 NCBI chr10:80,590,935...80,631,295
Ensembl chr10:80,591,040...80,631,295 		JBrowse link
G Dsg2 desmoglein 2 IAGP MGI PMID:27170944 NCBI chr18:20,691,247...20,737,583
Ensembl chr18:20,691,131...20,737,578 		JBrowse link
G Fgf2 fibroblast growth factor 2 IAGP MGI PMID:17150229 NCBI chr 3:37,402,616...37,464,255
Ensembl chr 3:37,402,495...37,464,257 		JBrowse link
G Gata4 GATA binding protein 4 IAGP MGI PMID:16514068 NCBI chr14:63,436,363...63,509,161
Ensembl chr14:63,436,371...63,509,141 		JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:25787764 PMID:27812542 PMID:31819041 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,054,294 		JBrowse link
G Hdac1 histone deacetylase 1 IAGP MGI PMID:17639084 NCBI chr 4:129,409,897...129,436,516
Ensembl chr 4:129,409,897...129,436,506 		JBrowse link
G Hdac2 histone deacetylase 2 IAGP MGI PMID:17639084 NCBI chr10:36,850,293...36,877,885
Ensembl chr10:36,850,540...36,877,885 		JBrowse link
G Hmox1 heme oxygenase 1 IAGP MGI PMID:10207174 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217 		JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U IAGP MGI PMID:26039991 NCBI chr 1:178,148,673...178,170,063
Ensembl chr 1:178,148,673...178,165,362 		JBrowse link
G Inpp5f inositol polyphosphate-5-phosphatase F IAGP MGI PMID:19875726 NCBI chr 7:128,212,905...128,298,161
Ensembl chr 7:128,213,052...128,298,149 		JBrowse link
G Ivns1abp influenza virus NS1A binding protein IAGP MGI PMID:15485691 NCBI chr 1:151,220,237...151,240,196
Ensembl chr 1:151,220,228...151,240,173 		JBrowse link
G Jup junction plakoglobin IAGP MGI PMID:21880664 NCBI chr11:100,259,682...100,288,639
Ensembl chr11:100,259,784...100,288,589 		JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 IAGP MGI PMID:12122119 NCBI chr13:111,882,962...111,954,803
Ensembl chr13:111,882,962...111,945,527 		JBrowse link
G Mapk1 mitogen-activated protein kinase 1 IAGP MGI PMID:15096454 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317 		JBrowse link
G Mapk14 mitogen-activated protein kinase 14 IAGP MGI PMID:15572667 NCBI chr17:28,910,316...28,967,379
Ensembl chr17:28,910,303...28,967,380 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 IAGP MGI PMID:16579967 NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115 		JBrowse link
G Mdm2 transformed mouse 3T3 cell double minute 2 IAGP MGI PMID:16354690 NCBI chr10:117,524,780...117,546,663
Ensembl chr10:117,524,780...117,546,663 		JBrowse link
G Mdm4 transformed mouse 3T3 cell double minute 4 IAGP MGI PMID:17533180 NCBI chr 1:132,913,843...132,958,325
Ensembl chr 1:132,887,222...132,958,299 		JBrowse link
G Med1 mediator complex subunit 1 IAGP MGI PMID:27548259 NCBI chr11:98,042,980...98,084,121
Ensembl chr11:98,042,980...98,084,119 		JBrowse link
G Mir133a-1 microRNA 133a-1 IAGP MGI PMID:19015276 NCBI chr18:10,782,909...10,782,976
Ensembl chr18:10,782,909...10,782,976 		JBrowse link
G Mir133a-2 microRNA 133a-2 IAGP MGI PMID:19015276 NCBI chr 2:180,040,172...180,040,275
Ensembl chr 2:180,040,172...180,040,275 		JBrowse link
G Mir214 microRNA 214 IAGP MGI PMID:22426211 NCBI chr 1:162,050,937...162,051,046
Ensembl chr 1:162,050,937...162,051,046 		JBrowse link
G Mtfp1 mitochondrial fission process 1 IAGP MGI PMID:36333300 NCBI chr11:4,041,481...4,045,431
Ensembl chr11:4,041,480...4,045,445 		JBrowse link
G Mtor mechanistic target of rapamycin kinase IAGP MGI PMID:20644257 NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140 		JBrowse link
G Myh10 myosin, heavy polypeptide 10, non-muscle IAGP MGI PMID:19815823 PMID:29084269 NCBI chr11:68,581,228...68,707,451
Ensembl chr11:68,582,385...68,707,458 		JBrowse link
G Myh6 myosin, heavy polypeptide 6, cardiac muscle, alpha IAGP MGI PMID:24829265 NCBI chr14:55,179,378...55,205,553
Ensembl chr14:55,179,378...55,204,384 		JBrowse link
G Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow IAGP MGI PMID:22082674 NCBI chr 5:122,230,787...122,251,536
Ensembl chr 5:122,239,014...122,251,535 		JBrowse link
G Myocd myocardin IAGP MGI PMID:19850880 NCBI chr11:65,064,434...65,160,821
Ensembl chr11:65,067,387...65,160,815 		JBrowse link
G Ndor1 NADPH dependent diflavin oxidoreductase 1 IAGP MGI PMID:24589777 NCBI chr 2:25,134,825...25,145,458
Ensembl chr 2:25,134,833...25,146,034
Ensembl chr 2:25,134,833...25,146,034
Ensembl chr 2:25,134,833...25,146,034 		JBrowse link
G Nkx2-5 NK2 homeobox 5 IAGP MGI PMID:16514068 PMID:25787764 NCBI chr17:27,057,638...27,063,962
Ensembl chr17:27,057,638...27,063,983 		JBrowse link
G Nol3 nucleolar protein 3 (apoptosis repressor with CARD domain) IAGP MGI PMID:16505176 NCBI chr 8:106,002,777...106,008,571
Ensembl chr 8:106,002,772...106,008,571 		JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 IAGP MGI PMID:22082674 NCBI chr 7:97,437,748...97,561,588
Ensembl chr 7:97,437,748...97,561,588 		JBrowse link
G Plrg1 pleiotropic regulator 1 IAGP MGI PMID:19307306 NCBI chr 3:82,962,845...82,979,598
Ensembl chr 3:82,962,829...82,979,662 		JBrowse link
G Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I) IAGP MGI PMID:32882262 NCBI chr11:17,109,298...17,150,380
Ensembl chr11:17,109,263...17,150,375 		JBrowse link
G Raf1 v-raf-leukemia viral oncogene 1 IAGP MGI PMID:15467832 NCBI chr 6:115,595,530...115,653,596
Ensembl chr 6:115,595,028...115,653,596 		JBrowse link
G Rap1gds1 RAP1, GTP-GDP dissociation stimulator 1 IAGP MGI PMID:10793158 NCBI chr 3:138,631,662...138,781,163
Ensembl chr 3:138,631,663...138,780,962 		JBrowse link
G Rasa1 RAS p21 protein activator 1 IAGP MGI PMID:22949508 NCBI chr13:85,362,893...85,437,487
Ensembl chr13:85,362,899...85,437,249 		JBrowse link
G Sirt7 sirtuin 7 IAGP MGI PMID:18239138 NCBI chr11:120,509,197...120,515,840
Ensembl chr11:120,509,198...120,516,066 		JBrowse link
G Slc8a1 solute carrier family 8 (sodium/calcium exchanger), member 1 IAGP MGI PMID:10967099 NCBI chr17:81,680,534...82,045,816
Ensembl chr17:81,680,534...82,045,806 		JBrowse link
G Smarcd3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 IAGP MGI PMID:29183906 NCBI chr 5:24,797,620...24,829,649
Ensembl chr 5:24,795,816...24,829,409 		JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial IAGP MGI PMID:15890620 PMID:19293248 NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950 		JBrowse link
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 IAGP MGI PMID:21041952 NCBI chr17:80,701,181...80,787,882
Ensembl chr17:80,701,180...80,787,882 		JBrowse link
G Srf serum response factor IAGP MGI PMID:15929941 NCBI chr17:46,857,764...46,869,194
Ensembl chr17:46,859,255...46,867,101 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 IAGP MGI PMID:12223448 NCBI chr 1:52,158,588...52,201,024
Ensembl chr 1:52,158,599...52,201,024 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 IAGP MGI PMID:14566054 PMID:17289576 NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366 		JBrowse link
G Syne1 spectrin repeat containing, nuclear envelope 1 IAGP MGI PMID:24586179 NCBI chr10:4,970,192...5,501,013
Ensembl chr10:4,970,917...5,501,482 		JBrowse link
G Syne2 spectrin repeat containing, nuclear envelope 2 IAGP MGI PMID:24586179 NCBI chr12:75,865,092...76,157,702
Ensembl chr12:75,864,908...76,157,700 		JBrowse link
G Tcap titin-cap IAGP MGI PMID:21799151 NCBI chr11:98,274,637...98,275,779
Ensembl chr11:98,274,637...98,275,779 		JBrowse link
G Terc telomerase RNA component IAGP MGI PMID:12505991 NCBI chr 3:96,321,753...96,322,149
Ensembl chr 3:96,321,753...96,322,149 		JBrowse link
G Tfam transcription factor A, mitochondrial IAGP MGI PMID:11259653 NCBI chr10:71,061,298...71,074,157
Ensembl chr10:71,061,294...71,074,110 		JBrowse link
G Trim54 tripartite motif-containing 54 IAGP MGI PMID:17360532 NCBI chr 5:31,273,956...31,294,970
Ensembl chr 5:31,274,056...31,294,974 		JBrowse link
G Ube4b ubiquitination factor E4B IAGP MGI PMID:16314518 NCBI chr 4:149,412,873...149,512,618
Ensembl chr 4:149,412,873...149,511,206 		JBrowse link
G Uvrag UV radiation resistance associated gene IAGP MGI PMID:24081163 NCBI chr 7:98,535,949...98,790,373
Ensembl chr 7:98,534,228...98,790,348 		JBrowse link
G Wwtr1 WW domain containing transcription regulator 1 IAGP MGI PMID:23918388 NCBI chr 3:57,363,065...57,483,331
Ensembl chr 3:57,363,070...57,483,331 		JBrowse link
G Xirp2 xin actin-binding repeat containing 2 IAGP MGI PMID:20360251 NCBI chr 2:67,276,343...67,356,964
Ensembl chr 2:67,004,178...67,356,959 		JBrowse link
G Yap1 yes-associated protein 1 IAGP MGI PMID:23918388 NCBI chr 9:7,932,000...8,004,890
Ensembl chr 9:7,932,000...8,004,597 		JBrowse link
G Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta IAGP MGI PMID:17145769 NCBI chr12:21,440,330...21,467,437
Ensembl chr12:21,440,072...21,467,638 		JBrowse link
G Zfpm2 zinc finger protein, multitype 2 IAGP MGI PMID:19411759 NCBI chr15:40,518,438...40,967,988
Ensembl chr15:40,518,431...40,967,988 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16734
    muscle phenotype 1953
      abnormal muscle physiology 1232
        abnormal cardiomyocyte apoptosis 90
          increased cardiomyocyte apoptosis 74
Path 2
Term Annotations click to browse term
  mammalian phenotype 16734
    cellular phenotype 5391
      abnormal cell physiology 4790
        abnormal cell death 2117
          abnormal programmed cell death 1731
            abnormal apoptosis 1725
              abnormal cardiomyocyte apoptosis 90
                increased cardiomyocyte apoptosis 74
paths to the root