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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal cardiomyocyte apoptosis
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Accession:MP:0003221 term browser browse the term
Definition:change in the timing or the number of cardiac muscle cells undergoing programmed cell death



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decreased cardiomyocyte apoptosis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1rl2 interleukin 1 receptor-like 2 IMP compared to Wild Type in cardiopulmonary bypass model RGD PMID:32048631 RGD:126925167 NCBI chr 9:42,591,658...42,639,351
Ensembl chr 9:42,591,934...42,636,667
JBrowse link
G Il1rl2tm1(Myh6-cre)Mhzh interleukin 1 receptor-like 2; tm1 (Myh6-cre), Mhzh IMP compared to Wild Type in cardiopulmonary bypass model RGD PMID:32048631 RGD:126925167
increased cardiomyocyte apoptosis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kdm6a lysine demethylase 6A IMP mRNA:incr expr:myocardium (rat) RGD PMID:30887465 RGD:151665136 NCBI chr  X:4,337,466...4,477,100
Ensembl chr  X:4,337,750...4,477,062
JBrowse link
G Ubd ubiquitin D IMP associated with induced myocardial infarction RGD PMID:29438664 RGD:126925221 NCBI chr20:1,385,487...1,387,438
Ensembl chr20:1,385,864...1,408,639
Ensembl chr20:1,385,864...1,408,639
JBrowse link
G Ubdem1 ubiquitin D; CRISPR/Cas9 induced mutant1 IMP associated with induced myocardial infarction RGD PMID:29438664 RGD:126925221

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5372
    muscle phenotype 190
      abnormal muscle physiology 117
        abnormal cardiomyocyte apoptosis 7
          decreased cardiomyocyte apoptosis 3
          increased cardiomyocyte apoptosis 4
Path 2
Term Annotations click to browse term
  mammalian phenotype 5372
    cellular phenotype 174
      abnormal cell physiology 138
        abnormal cell death 58
          abnormal apoptosis 42
            abnormal cardiomyocyte apoptosis 7
              decreased cardiomyocyte apoptosis 3
              increased cardiomyocyte apoptosis 4
paths to the root