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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:persistent cloaca
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Accession:MP:0003129 term browser browse the term
Definition:persistence of an early embryonic state in which the urinary, genital, and gastrointestinal tracts remain confluent and communicate with the exterior through a single perineal opening; due to failure of the urogenital septum to divide the embryonic cloaca into rectal and urogenital portions
Comment:Note that the term "urogenital sinus" may refer to the primitive urogenital sinus present as a transient developmental structure in most mammals or it may refer to a condition in which an unseptated cloaca persists in animals longer than normal.
Synonyms:exact_synonym: cloacogenic bladder;   congenital cloaca
 related_synonym: urogenital sinus


show annotations for term's descendants           Sort by:
persistent cloaca term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctnnb1 catenin beta 1 IAGP MGI PMID:22991437 NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573 		JBrowse link
G Efnb2 ephrin B2 IAGP MGI PMID:15223334 NCBI chr 8:8,667,235...8,711,242
Ensembl chr 8:8,667,434...8,711,242 		JBrowse link
G Etl4 enhancer trap locus 4 IAGP MGI PMID:9706697 NCBI chr 2:19,915,018...20,815,346
Ensembl chr 2:19,914,591...20,815,524 		JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:22991437 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,055,336 		JBrowse link
G Sall4 spalt like transcription factor 4 IAGP MGI PMID:17216607 NCBI chr 2:168,590,252...168,609,121
Ensembl chr 2:168,590,252...168,609,863 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 17108
    renal/urinary system phenotype 2157
      abnormal renal/urinary system morphology 1798
        persistent cloaca 5
Path 2
Term Annotations click to browse term
  mammalian phenotype 17108
    digestive/alimentary phenotype 1929
      abnormal digestive system morphology 1582
        abnormal digestive system development 117
          persistent cloaca 5
paths to the root