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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:decreased paired-pulse facilitation
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Accession:MP:0002920 term browser browse the term
Definition:reduction in the response of central synapses when activated twice in rapid succession; indicative of defects in short-term plasticity due to lack of increase of neurotransmitter release at the second stimulus
Synonyms:exact_synonym: reduced PPF;   reduced paired-pulse facilitation



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decreased paired-pulse facilitation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ank2 ankyrin 2, brain IAGP MGI PMID:31285321 NCBI chr 3:126,715,256...127,293,996
Ensembl chr 3:126,715,261...127,292,999
JBrowse link
G Atxn1 ataxin 1 IAGP MGI PMID:9651231 NCBI chr13:45,703,231...46,118,467
Ensembl chr13:45,703,231...46,118,484
JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha IAGP MGI PMID:1378648 NCBI chr18:61,058,704...61,121,224
Ensembl chr18:61,058,690...61,121,224
JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1, CNS IAGP MGI PMID:16290192 PMID:20080609 NCBI chr19:8,641,369...8,660,970
Ensembl chr19:8,641,153...8,660,951
JBrowse link
G Cul3 cullin 3 IAGP MGI PMID:31780330 NCBI chr 1:80,242,640...80,318,426
Ensembl chr 1:80,242,640...80,318,197
JBrowse link
G Emx1 empty spiracles homeobox 1 IAGP MGI PMID:20080609 NCBI chr 6:85,164,913...85,181,445
Ensembl chr 6:85,164,420...85,181,444
JBrowse link
G Fbxl20 F-box and leucine-rich repeat protein 20 IAGP MGI PMID:17803915 NCBI chr11:97,973,380...98,042,014
Ensembl chr11:97,973,382...98,041,229
JBrowse link
G Grik2 glutamate receptor, ionotropic, kainate 2 (beta 2) IAGP MGI PMID:11182092 PMID:17620617 NCBI chr10:48,969,776...49,666,523
Ensembl chr10:48,970,929...49,664,862
JBrowse link
G Grik3 glutamate receptor, ionotropic, kainate 3 IAGP MGI PMID:17620617 NCBI chr 4:125,384,025...125,607,966
Ensembl chr 4:125,384,493...125,607,966
JBrowse link
G Grik4 glutamate receptor, ionotropic, kainate 4 IAGP MGI PMID:19778510 NCBI chr 9:42,431,708...42,856,296
Ensembl chr 9:42,429,431...42,855,789
JBrowse link
G Grik5 glutamate receptor, ionotropic, kainate 5 (gamma 2) IAGP MGI PMID:19778510 NCBI chr 7:24,709,274...24,775,421
Ensembl chr 7:24,709,274...24,771,771
JBrowse link
G Grm4 glutamate receptor, metabotropic 4 IAGP MGI PMID:8815915 NCBI chr17:27,641,361...27,732,800
Ensembl chr17:27,641,361...27,740,377
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 IAGP MGI PMID:22096518 NCBI chr  X:52,076,955...52,110,537
Ensembl chr  X:52,077,014...52,110,536
JBrowse link
G Htr1a 5-hydroxytryptamine (serotonin) receptor 1A IAGP MGI PMID:10751426 PMID:11121072 NCBI chr13:105,580,040...105,584,630
Ensembl chr13:105,580,147...105,584,630
JBrowse link
G Htt huntingtin IAGP MGI PMID:24728353 NCBI chr 5:34,919,084...35,069,878
Ensembl chr 5:34,919,084...35,069,878
JBrowse link
G Ip6k1 inositol hexaphosphate kinase 1 IAGP MGI PMID:32252022 NCBI chr 9:107,879,847...107,925,981
Ensembl chr 9:107,879,700...107,925,981
JBrowse link
G Lrrtm3 leucine rich repeat transmembrane neuronal 3 IAGP MGI PMID:26776509 NCBI chr10:63,764,276...63,926,034
Ensembl chr10:63,764,251...63,926,056
JBrowse link
G Lynx1 Ly6/neurotoxin 1 IAGP MGI PMID:16950157 NCBI chr15:74,619,705...74,624,828
Ensembl chr15:74,619,701...74,624,895
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 IAGP MGI PMID:15816869 NCBI chr11:49,737,558...49,777,248
Ensembl chr11:49,737,578...49,777,248
JBrowse link
G Pdzd8 PDZ domain containing 8 IAGP MGI PMID:35227461 NCBI chr19:59,284,516...59,334,212
Ensembl chr19:59,285,610...59,334,212
JBrowse link
G Pfn2 profilin 2 IAGP MGI PMID:17541406 NCBI chr 3:57,749,316...57,755,178
Ensembl chr 3:57,749,316...57,755,500
JBrowse link
G Psen1 presenilin 1 IAGP MGI PMID:25741723 NCBI chr12:83,734,926...83,781,869
Ensembl chr12:83,734,926...83,781,973
JBrowse link
G Psen2 presenilin 2 IAGP MGI PMID:25741723 NCBI chr 1:180,054,569...180,091,030
Ensembl chr 1:180,054,569...180,091,003
JBrowse link
G Rap1a RAS-related protein 1a IAGP MGI PMID:18305243 NCBI chr 3:105,634,576...105,708,740
Ensembl chr 3:105,634,583...105,708,652
JBrowse link
G Rap1b RAS related protein 1b IAGP MGI PMID:18305243 NCBI chr10:117,650,502...117,681,879
Ensembl chr10:117,649,776...117,681,940
JBrowse link
G Rbfox3 RNA binding protein, fox-1 homolog (C. elegans) 3 IAGP MGI PMID:26619789 NCBI chr11:118,380,586...118,802,423
Ensembl chr11:118,380,588...118,802,423
JBrowse link
G Rims1 regulating synaptic membrane exocytosis 1 IAGP MGI PMID:11797009 NCBI chr 1:22,356,196...22,845,239
Ensembl chr 1:22,356,475...22,845,203
JBrowse link
G Rnf112 ring finger protein 112 IAGP MGI PMID:26212327 NCBI chr11:61,339,243...61,345,014
Ensembl chr11:61,339,268...61,344,957
JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 IAGP MGI PMID:18718479 NCBI chr12:16,944,808...17,038,275
Ensembl chr12:16,944,896...17,037,824
JBrowse link
G Sct secretin IAGP MGI PMID:18534766 NCBI chr 7:140,858,243...140,859,082
Ensembl chr 7:140,858,243...140,859,046
JBrowse link
G Snap25 synaptosomal-associated protein 25 IAGP MGI PMID:19043548 NCBI chr 2:136,555,359...136,624,348
Ensembl chr 2:136,555,373...136,624,348
JBrowse link
G Stxbp5l syntaxin binding protein 5-like IAGP MGI PMID:24744148 NCBI chr16:36,927,437...37,205,377
Ensembl chr16:36,935,304...37,205,324
JBrowse link
G Syngr1 synaptogyrin 1 IAGP MGI PMID:10595519 NCBI chr15:79,975,537...80,003,702
Ensembl chr15:79,975,535...80,003,702
JBrowse link
G Syp synaptophysin IAGP MGI PMID:10595519 NCBI chr  X:7,504,819...7,519,495
Ensembl chr  X:7,504,710...7,519,495
JBrowse link
G Uchl1 ubiquitin carboxy-terminal hydrolase L1 IAGP MGI PMID:20080621 NCBI chr 5:66,833,464...66,844,577
Ensembl chr 5:66,833,434...66,844,577
JBrowse link
G Usp14 ubiquitin specific peptidase 14 IAGP MGI PMID:12368914 PMID:18771733 NCBI chr18:9,993,615...10,030,149
Ensembl chr18:9,993,066...10,045,119
JBrowse link
G Vdac1 voltage-dependent anion channel 1 IAGP MGI PMID:11907043 NCBI chr11:52,251,905...52,280,224
Ensembl chr11:52,251,687...52,280,224
JBrowse link
G Vdac3 voltage-dependent anion channel 3 IAGP MGI PMID:11907043 NCBI chr 8:23,067,091...23,083,829
Ensembl chr 8:23,067,102...23,083,774
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 17090
    nervous system phenotype 4651
      abnormal nervous system physiology 2729
        abnormal synaptic physiology 1238
          abnormal synaptic transmission 1229
            abnormal paired-pulse facilitation 89
              decreased paired-pulse facilitation 38
paths to the root