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ONTOLOGY REPORT - ANNOTATIONS


Term:increased IgM level
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Accession:MP:0002494 term browser browse the term
Definition:greater than normal immunoglobulin class M level
Synonyms:narrow_synonym: increased serum level of immunoglobulin M
 alt_id: MP:0001813


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increased IgM level term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aicda activation-induced cytidine deaminase JBrowse link 6 122,553,809 122,564,180 RGD:5509061
G Apoe apolipoprotein E JBrowse link 7 19,696,244 19,701,310 RGD:5509061
G Ash1l ASH1 like histone lysine methyltransferase JBrowse link 3 88,950,414 89,079,375 RGD:5509061
G Atm ataxia telangiectasia mutated JBrowse link 9 53,437,122 53,536,828 RGD:5509061
G B2m beta-2 microglobulin JBrowse link 2 122,147,687 122,153,082 RGD:5509061
G Bach2 BTB and CNC homology, basic leucine zipper transcription factor 2 JBrowse link 4 32,238,413 32,586,109 RGD:5509061
G Bak1 BCL2-antagonist/killer 1 JBrowse link 17 27,019,812 27,028,627 RGD:5509061
G Bank1 B cell scaffold protein with ankyrin repeats 1 JBrowse link 3 136,053,363 136,326,141 RGD:5509061
G Bax BCL2-associated X protein JBrowse link 7 45,461,695 45,466,903 RGD:5509061
G Bcl10 B cell leukemia/lymphoma 10 JBrowse link 3 145,924,262 145,934,366 RGD:5509061
G Bcl2l11 BCL2-like 11 (apoptosis facilitator) JBrowse link 2 128,126,038 128,162,547 RGD:5509061
G Bcl3 B cell leukemia/lymphoma 3 JBrowse link 7 19,808,462 19,822,824 RGD:5509061
G Birc3 baculoviral IAP repeat-containing 3 JBrowse link 9 7,847,468 7,873,205 RGD:5509061
G Blnk B cell linker JBrowse link 19 40,928,927 40,994,221 RGD:5509061
G Btk Bruton agammaglobulinemia tyrosine kinase JBrowse link X 134,542,334 134,583,628 RGD:5509061
G C3 complement component 3 JBrowse link 17 57,203,967 57,228,136 RGD:5509061
G C9orf72 C9orf72, member of C9orf72-SMCR8 complex JBrowse link 4 35,191,285 35,226,153 RGD:5509061
G Ccr6 chemokine (C-C motif) receptor 6 JBrowse link 17 8,236,041 8,258,519 RGD:5509061
G Cd19 CD19 antigen JBrowse link 7 126,408,448 126,415,148 RGD:5509061
G Cd209b CD209b antigen JBrowse link 8 3,917,655 3,926,841 RGD:5509061
G Cd22 CD22 antigen JBrowse link 7 30,865,404 30,880,342 RGD:5509061
G Cd4 CD4 antigen JBrowse link 6 124,864,693 124,888,247 RGD:5509061
G Cd69 CD69 antigen JBrowse link 6 129,267,324 129,275,375 RGD:5509061
G Cd72 CD72 antigen JBrowse link 4 43,447,724 43,455,102 RGD:5509061
G Cd79a CD79A antigen (immunoglobulin-associated alpha) JBrowse link 7 24,897,497 24,901,858 RGD:5509061
G Cd79b CD79B antigen JBrowse link 11 106,311,341 106,314,562 RGD:5509061
G Cd80 CD80 antigen JBrowse link 16 38,457,430 38,495,958 RGD:5509061
G Cd81 CD81 antigen JBrowse link 7 143,052,750 143,067,930 RGD:5509061
G Cd86 CD86 antigen JBrowse link 16 36,568,956 36,666,158 RGD:5509061
G Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) JBrowse link 17 29,090,979 29,100,722 RGD:5509061
G Ciita class II transactivator JBrowse link 16 10,480,014 10,531,064 RGD:5509061
G Commd10 COMM domain containing 10 JBrowse link 18 46,958,819 47,087,995 RGD:5509061
G Cr2 complement receptor 2 JBrowse link 1 195,136,811 195,176,880 RGD:5509061
G Cxcr4 chemokine (C-X-C motif) receptor 4 JBrowse link 1 128,588,199 128,592,299 RGD:5509061
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 JBrowse link 7 112,116,019 112,159,482 RGD:5509061
G Dlk1 delta like non-canonical Notch ligand 1 JBrowse link 12 109,452,485 109,463,336 RGD:5509061
G Dock2 dedicator of cyto-kinesis 2 JBrowse link 11 34,226,815 34,783,905 RGD:5509061
G Dok3 docking protein 3 JBrowse link 13 55,523,231 55,530,345 RGD:5509061
G Ebf1 early B cell factor 1 JBrowse link 11 44,618,100 45,008,096 RGD:5509061
G Efhd2 EF hand domain containing 2 JBrowse link 4 141,858,142 141,874,920 RGD:5509061
G Fas Fas (TNF receptor superfamily member 6) JBrowse link 19 34,290,647 34,327,775 RGD:5509061
G Fcer2a Fc receptor, IgE, low affinity II, alpha polypeptide JBrowse link 8 3,680,280 3,694,174 RGD:5509061
G Fcgr2b Fc receptor, IgG, low affinity IIb JBrowse link 1 170,960,558 170,976,071 RGD:5509061
G Fcmr Fc fragment of IgM receptor JBrowse link 1 130,865,777 130,880,790 RGD:5509061
G Flt3l FMS-like tyrosine kinase 3 ligand JBrowse link 7 45,131,183 45,136,490 RGD:5509061
G Foxp3 forkhead box P3 JBrowse link X 7,579,676 7,595,243 RGD:5509061
G Fyn Fyn proto-oncogene JBrowse link 10 39,369,743 39,565,381 RGD:5509061
G Gabpb2 GA repeat binding protein, beta 2 JBrowse link 3 95,181,766 95,218,110 RGD:5509061
G Gadd45a growth arrest and DNA-damage-inducible 45 alpha JBrowse link 6 67,035,096 67,037,407 RGD:5509061
G Gadd45b growth arrest and DNA-damage-inducible 45 beta JBrowse link 10 80,930,091 80,932,204 RGD:5509061
G Gadd45g growth arrest and DNA-damage-inducible 45 gamma JBrowse link 13 51,846,675 51,848,475 RGD:5509061
G Gapt Grb2-binding adaptor, transmembrane JBrowse link 13 110,352,614 110,357,220 RGD:5509061
G Ggta1 glycoprotein galactosyltransferase alpha 1, 3 JBrowse link 2 35,400,179 35,464,381 RGD:5509061
G Gnai2 guanine nucleotide binding protein (G protein), alpha inhibiting 2 JBrowse link 9 107,614,125 107,635,391 RGD:5509061
G Grb2 growth factor receptor bound protein 2 JBrowse link 11 115,644,045 115,708,597 RGD:5509061
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano JBrowse link 6 113,067,428 113,077,244 RGD:5509061
G H2-Ab1 histocompatibility 2, class II antigen A, beta 1 JBrowse link 17 34,263,227 34,269,418 RGD:5509061
G Hrh1 histamine receptor H1 JBrowse link 6 114,397,936 114,483,298 RGD:5509061
G Ifih1 interferon induced with helicase C domain 1 JBrowse link 2 62,595,618 62,646,255 RGD:5509061
G Ifnar1 interferon (alpha and beta) receptor 1 JBrowse link 16 91,485,032 91,510,523 RGD:5509061
G Igh immunoglobulin heavy chain complex JBrowse link 12 113,258,768 116,009,954 RGD:5509061
G Igh-7 immunoglobulin heavy chain 7 (heavy chain of IgE) RGD:5509061
G Igh-8 immunoglobulin heavy chain 8 (heavy chain of IgG3) RGD:5509061
G Igha immunoglobulin heavy constant alpha JBrowse link 12 113,256,204 113,260,236 RGD:5509061
G Ighg1 immunoglobulin heavy constant gamma 1 (G1m marker) JBrowse link 12 113,326,541 113,330,523 RGD:5509061
G Ighm immunoglobulin heavy constant mu JBrowse link 12 113,418,826 113,422,730 RGD:5509061
G Igkj1 immunoglobulin kappa joining 1 JBrowse link 6 70,722,562 70,722,599 RGD:5509061
G Il13 interleukin 13 JBrowse link 11 53,631,323 53,634,702 RGD:5509061
G Il2rb interleukin 2 receptor, beta chain JBrowse link 15 78,479,256 78,511,621 RGD:5509061
G Il4 interleukin 4 JBrowse link 11 53,612,460 53,618,665 RGD:5509061
G Il5ra interleukin 5 receptor, alpha JBrowse link 6 106,710,375 106,749,037 RGD:5509061
G Il6st interleukin 6 signal transducer JBrowse link 13 112,464,070 112,506,860 RGD:5509061
G Inpp5d inositol polyphosphate-5-phosphatase D JBrowse link 1 87,620,312 87,720,510 RGD:5509061
G Itfg2 integrin alpha FG-GAP repeat containing 2 JBrowse link 6 128,409,047 128,424,927 RGD:5509061
G Itgb2 integrin beta 2 JBrowse link 10 77,530,329 77,565,708 RGD:5509061
G Jak1 Janus kinase 1 JBrowse link 4 101,151,974 101,265,282 RGD:5509061
G Kit KIT proto-oncogene receptor tyrosine kinase JBrowse link 5 75,574,987 75,656,722 RGD:5509061
G Klra8 killer cell lectin-like receptor, subfamily A, member 8 JBrowse link 6 130,115,226 130,129,898 RGD:5509061
G Lama2 laminin, alpha 2 JBrowse link 10 26,981,285 27,617,191 RGD:5509061
G Lama5 laminin, alpha 5 JBrowse link 2 180,176,373 180,225,904 RGD:5509061
G Lat linker for activation of T cells JBrowse link 7 126,363,827 126,369,705 RGD:5509061
G Ldlr low density lipoprotein receptor JBrowse link 9 21,723,576 21,749,919 RGD:5509061
G Lta lymphotoxin A JBrowse link 17 35,203,165 35,205,578 RGD:5509061
G Ltb lymphotoxin B JBrowse link 17 35,194,507 35,196,305 RGD:5509061
G Ly86 lymphocyte antigen 86 JBrowse link 13 37,345,345 37,419,036 RGD:5509061
G Lyn LYN proto-oncogene, Src family tyrosine kinase JBrowse link 4 3,678,068 3,791,612 RGD:5509061
G Lyz2 lysozyme 2 JBrowse link 10 117,277,541 117,282,272 RGD:5509061
G Man2a1 mannosidase 2, alpha 1 JBrowse link 17 64,600,688 64,755,110 RGD:5509061
G Marco macrophage receptor with collagenous structure JBrowse link 1 120,474,538 120,505,024 RGD:5509061
G Mavs mitochondrial antiviral signaling protein JBrowse link 2 131,234,063 131,248,025 RGD:5509061
G Metrnl meteorin, glial cell differentiation regulator-like JBrowse link 11 121,702,427 121,717,389 RGD:5509061
G Mir150 microRNA 150 JBrowse link 7 45,121,757 45,121,821 RGD:5509061
G Mlh1 mutL homolog 1 JBrowse link 9 111,228,228 111,271,786 RGD:5509061
G Msr1 macrophage scavenger receptor 1 JBrowse link 8 39,543,232 39,642,750 RGD:5509061
G Mt2 metallothionein 2 JBrowse link 8 94,172,618 94,173,567 RGD:5509061
G Myd88 myeloid differentiation primary response gene 88 JBrowse link 9 119,335,934 119,340,018 RGD:5509061
G Nedd4 neural precursor cell expressed, developmentally down-regulated 4 JBrowse link 9 72,662,331 72,749,851 RGD:5509061
G Nfatc1 nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1 JBrowse link 18 80,606,205 80,713,071 RGD:5509061
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 JBrowse link 2 75,675,513 75,704,663 RGD:5509061
G Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100 JBrowse link 19 46,300,994 46,312,400 RGD:5509061
G Nfkbie nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon JBrowse link 17 45,555,700 45,563,169 RGD:5509061
G Nhej1 non-homologous end joining factor 1 JBrowse link 1 74,967,346 75,125,226 RGD:5509061
G Nipal3 NIPA-like domain containing 3 JBrowse link 4 135,442,805 135,494,972 RGD:5509061
G Npy1r neuropeptide Y receptor Y1 JBrowse link 8 66,697,149 66,706,800 RGD:5509061
G Ntrk1 neurotrophic tyrosine kinase, receptor, type 1 JBrowse link 3 87,778,244 87,795,242 RGD:5509061
G Otc ornithine transcarbamylase JBrowse link X 10,252,230 10,321,024 RGD:5509061
G Pdcd1 programmed cell death 1 JBrowse link 1 94,038,305 94,052,553 RGD:5509061
G Pdcd1lg2 programmed cell death 1 ligand 2 JBrowse link 19 29,410,919 29,472,927 RGD:5509061
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 JBrowse link 19 41,272,541 41,385,102 RGD:5509061
G Pik3c2a phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha JBrowse link 7 116,337,265 116,443,465 RGD:5509061
G Pkn1 protein kinase N1 JBrowse link 8 83,666,533 83,699,181 RGD:5509061
G Plcl2 phospholipase C-like 2 JBrowse link 17 50,508,865 50,688,494 RGD:5509061
G Pld4 phospholipase D family, member 4 JBrowse link 12 112,760,446 112,768,986 RGD:5509061
G Pnp purine-nucleoside phosphorylase JBrowse link 14 50,944,303 50,953,412 RGD:5509061
G Pou2af1 POU domain, class 2, associating factor 1 JBrowse link 9 51,213,690 51,240,079 RGD:5509061
G Pparg peroxisome proliferator activated receptor gamma JBrowse link 6 115,360,879 115,490,404 RGD:5509061
G Prkcd protein kinase C, delta JBrowse link 14 30,595,353 30,626,414 RGD:5509061
G Prkdc protein kinase, DNA activated, catalytic polypeptide JBrowse link 16 15,637,444 15,842,239 RGD:5509061
G Pten phosphatase and tensin homolog JBrowse link 19 32,757,577 32,826,160 RGD:5509061
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 1 150,100,031 150,108,234 RGD:5509061
G Rac2 Rac family small GTPase 2 JBrowse link 15 78,559,169 78,572,783 RGD:5509061
G Rasgrp1 RAS guanyl releasing protein 1 JBrowse link 2 117,279,983 117,342,877 RGD:5509061
G Rel reticuloendotheliosis oncogene JBrowse link 11 23,736,847 23,770,969 RGD:5509061
G Relb avian reticuloendotheliosis viral (v-rel) oncogene related B JBrowse link 7 19,606,217 19,629,438 RGD:5509061
G Rgs13 regulator of G-protein signaling 13 JBrowse link 1 144,137,386 144,177,372 RGD:5509061
G Rnf128 ring finger protein 128 JBrowse link X 139,563,340 139,673,145 RGD:5509061
G Rxra retinoid X receptor alpha JBrowse link 2 27,676,445 27,763,319 RGD:5509061
G Samsn1 SAM domain, SH3 domain and nuclear localization signals, 1 JBrowse link 16 75,858,794 75,909,266 RGD:5509061
G Siae sialic acid acetylesterase JBrowse link 9 37,613,821 37,648,258 RGD:5509061
G Siglecg sialic acid binding Ig-like lectin G JBrowse link 7 43,408,192 43,418,349 RGD:5509061
G Spi1 spleen focus forming virus (SFFV) proviral integration oncogene JBrowse link 2 91,082,368 91,115,759 RGD:5509061
G Spib Spi-B transcription factor (Spi-1/PU.1 related) JBrowse link 7 44,525,995 44,532,087 RGD:5509061
G Spp1 secreted phosphoprotein 1 JBrowse link 5 104,435,111 104,441,053 RGD:5509061
G Sting1 stimulator of interferon response cGAMP interactor 1 JBrowse link 18 35,733,678 35,740,554 RGD:5509061
G Stk4 serine/threonine kinase 4 JBrowse link 2 164,074,113 164,155,524 RGD:5509061
G Syk spleen tyrosine kinase JBrowse link 13 52,582,610 52,648,792 RGD:5509061
G Tank TRAF family member-associated Nf-kappa B activator JBrowse link 2 61,578,560 61,654,171 RGD:5509061
G Tbk1 TANK-binding kinase 1 JBrowse link 10 121,546,455 121,586,794 RGD:5509061
G Tbx21 T-box 21 JBrowse link 11 97,098,007 97,115,331 RGD:5509061
G Tcirg1 T cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3 JBrowse link 19 3,896,050 3,907,133 RGD:5509061
G Tcrb T cell receptor beta chain JBrowse link 6 40,891,296 41,558,371 RGD:5509061
G Tcrd T cell receptor delta chain JBrowse link 14 53,946,073 54,159,198 RGD:5509061
G Tgfbr2 transforming growth factor, beta receptor II JBrowse link 9 116,087,695 116,175,363 RGD:5509061
G Tlr7 toll-like receptor 7 JBrowse link X 167,303,380 167,330,574 RGD:5509061
G Tlr8 toll-like receptor 8 JBrowse link X 167,241,123 167,264,329 RGD:5509061
G Tnf tumor necrosis factor JBrowse link 17 35,199,367 35,202,007 RGD:5509061
G Tnfaip3 tumor necrosis factor, alpha-induced protein 3 JBrowse link 10 19,000,910 19,015,410 RGD:5509061
G Tnfrsf21 tumor necrosis factor receptor superfamily, member 21 JBrowse link 17 43,016,555 43,089,188 RGD:5509061
G Tnip1 TNFAIP3 interacting protein 1 JBrowse link 11 54,910,787 54,962,956 RGD:5509061
G Traf3 TNF receptor-associated factor 3 JBrowse link 12 111,166,321 111,267,155 RGD:5509061
G Traf3ip2 TRAF3 interacting protein 2 JBrowse link 10 39,612,934 39,655,307 RGD:5509061
G Ung uracil DNA glycosylase JBrowse link 5 114,130,366 114,139,321 RGD:5509061
G Vav1 vav 1 oncogene JBrowse link 17 57,279,100 57,329,236 RGD:5509061
G Vsir V-set immunoregulatory receptor JBrowse link 10 60,346,851 60,430,294 RGD:5509061
G Was Wiskott-Aldrich syndrome JBrowse link X 8,081,466 8,090,491 RGD:5509061
G Wipf1 WAS/WASL interacting protein family, member 1 JBrowse link 2 73,429,610 73,529,487 RGD:5509061
G Zc3h12c zinc finger CCCH type containing 12C JBrowse link 9 52,109,569 52,168,730 RGD:5509061
G Zfp318 zinc finger protein 318 JBrowse link 17 46,383,515 46,420,920 RGD:5509061

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 13553
    immune system phenotype 4158
      abnormal immune system physiology 2917
        abnormal immune serum protein physiology 1226
          abnormal immunoglobulin level 614
            increased immunoglobulin level 390
              increased IgM level 173
Path 2
Term Annotations click to browse term
  mammalian phenotype 13553
    immune system phenotype 4158
      abnormal immune system physiology 2917
        abnormal immune cell physiology 1561
          abnormal leukocyte physiology 1526
            abnormal lymphocyte physiology 1149
              abnormal B cell physiology 735
                abnormal immunoglobulin level 614
                  increased immunoglobulin level 390
                    increased IgM level 173
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.