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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:impaired complement classical pathway
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Accession:MP:0002473 term browser browse the term
Definition:abnormal function of the plasma protein cascade triggered by antigen:antibody complexes


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impaired complement classical pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C9 complement component 9 IAGP MGI PMID:27444648 NCBI chr15:6,474,827...6,528,306
Ensembl chr15:6,474,808...6,528,232 		JBrowse link
G Cd55 CD55 molecule, decay accelerating factor for complement IAGP MGI PMID:9892684 NCBI chr 1:130,357,526...130,390,513
Ensembl chr 1:130,366,764...130,390,481 		JBrowse link
G Cfb complement factor B IAGP MGI PMID:17916747 NCBI chr17:35,075,350...35,081,492
Ensembl chr17:35,075,350...35,081,494 		JBrowse link
G Cfp complement factor properdin IAGP MGI PMID:17916747 NCBI chr  X:20,791,693...20,797,794
Ensembl chr  X:20,791,693...20,797,794 		JBrowse link
G Ighm immunoglobulin heavy constant mu IAGP MGI PMID:21987785 NCBI chr12:113,382,446...113,386,350
Ensembl chr12:113,382,178...113,386,350 		JBrowse link
G Jchain immunoglobulin joining chain IAGP MGI PMID:9710213 NCBI chr 5:88,667,663...88,675,667
Ensembl chr 5:88,667,668...88,675,750 		JBrowse link
G Prkdc protein kinase, DNA activated, catalytic polypeptide IAGP MGI PMID:7995938 NCBI chr16:15,455,698...15,660,103
Ensembl chr16:15,455,730...15,660,099 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16962
    immune system phenotype 5703
      abnormal immune system physiology 3483
        abnormal innate immunity 761
          abnormal complement pathway 32
            impaired complement classical pathway 7
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