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Pathways
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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal complement pathway
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Accession:MP:0002471 term browser browse the term
Definition:impaired ability of the complement proteins to act sequentially to directly kill microbes, dispose of immune complexes, and regulate other immune processes
Synonyms:exact_synonym: complement cascade dysfunction
 related_synonym: abnormal complement activation;   abnormal complement cascade;   abnormal complement response
 xref: GO:0006956


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  mammalian phenotype 0
    immune system phenotype 0
      abnormal immune system physiology 0
        abnormal innate immunity 0
          abnormal complement pathway 0
            abnormal complement protein level + 0
            decreased serum complement activity 0
            impaired complement alternative pathway 0
            impaired complement classical pathway 0
            impaired lectin complement pathway 0
            increased serum complement activity 0
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