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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal macrophage physiology
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Accession:MP:0002451 term browser browse the term
Definition:any functional anomaly of the large mononuclear phagocytes which differentiate from monocytes, are typically resident in a particular tissue, and capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells
Synonyms:exact_synonym: macrophage dysfunction



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Path 1
Term Annotations click to browse term
  mammalian phenotype 8
    immune system phenotype 0
      abnormal immune system physiology 0
        abnormal innate immunity 0
          abnormal macrophage physiology 0
            abnormal macrophage activation involved in immune response 0
            abnormal macrophage antigen presentation + 0
            abnormal macrophage apoptosis + 0
            abnormal macrophage chemotaxis + 0
            abnormal macrophage cytokine production + 0
            abnormal macrophage nitric oxide production + 0
            abnormal macrophage proliferation + 0
            abnormal microglial cell physiology + 0
            abnormal osteoclast physiology 0
            hemophagocytosis 0
            impaired macrophage phagocytosis 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 8
    immune system phenotype 0
      abnormal immune system physiology 0
        abnormal cell-mediated immunity 0
          abnormal leukocyte physiology 0
            abnormal macrophage physiology 0
              abnormal macrophage activation involved in immune response 0
              abnormal macrophage antigen presentation + 0
              abnormal macrophage apoptosis + 0
              abnormal macrophage chemotaxis + 0
              abnormal macrophage cytokine production + 0
              abnormal macrophage nitric oxide production + 0
              abnormal macrophage proliferation + 0
              abnormal microglial cell physiology + 0
              abnormal osteoclast physiology 0
              hemophagocytosis 0
              impaired macrophage phagocytosis 0
paths to the root