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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:increased intestinal adenoma incidence
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Accession:MP:0002404 term browser browse the term
Definition:greater than the expected number of a benign epithelial neoplasm with a glandular organization arising in the small and/or large intestine, occurring in a specific population in a given time period
Synonyms:exact_synonym: increased intestinal adenomata incidence;   increased intestine adenoma incidence



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increased intestinal adenoma incidence term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC, WNT signaling pathway regulator IAGP MGI PMID:1541640 PMID:2296722 PMID:7753829 PMID:8090754 PMID:8674041 More... NCBI chr18:34,353,350...34,455,243
Ensembl chr18:34,353,977...34,455,605
JBrowse link
G B3gnt6 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 IAGP MGI PMID:17517967 NCBI chr 7:97,841,622...97,848,682
Ensembl chr 7:97,841,624...97,848,688
JBrowse link
G Blm Bloom syndrome, RecQ like helicase IAGP MGI PMID:12242442 NCBI chr 7:80,104,839...80,184,896
Ensembl chr 7:80,104,481...80,184,867
JBrowse link
G Bmi1 Bmi1 polycomb ring finger oncogene IAGP MGI PMID:18536716 PMID:23955081 NCBI chr 2:18,681,953...18,691,440
Ensembl chr 2:18,681,829...18,691,440
JBrowse link
G Braf Braf transforming gene IAGP MGI PMID:22892241 PMID:23845441 NCBI chr 6:39,580,171...39,702,592
Ensembl chr 6:39,580,171...39,702,397
JBrowse link
G Ccnd1 cyclin D1 IAGP MGI PMID:12183406 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662
JBrowse link
G Cd44 CD44 antigen IAGP MGI PMID:23318432 NCBI chr 2:102,641,486...102,732,014
Ensembl chr 2:102,641,486...102,732,010
JBrowse link
G Cdhr5 cadherin-related family member 5 IAGP MGI PMID:33188295 NCBI chr 7:140,848,993...140,856,708
Ensembl chr 7:140,848,996...140,856,699
JBrowse link
G Cdkn2a cyclin dependent kinase inhibitor 2A IAGP MGI PMID:23845441 PMID:23955081 NCBI chr 4:89,192,710...89,212,856
Ensembl chr 4:89,192,708...89,212,890
JBrowse link
G Cdx2 caudal type homeobox 2 IAGP MGI PMID:9052785 NCBI chr 5:147,237,710...147,244,059
Ensembl chr 5:147,237,615...147,244,080
JBrowse link
G Ctnnb1 catenin beta 1 IAGP MGI PMID:10545105 PMID:18536716 PMID:21205788 PMID:21307168 NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573
JBrowse link
G Dcc deleted in colorectal carcinoma IAGP MGI PMID:9126737 PMID:22158121 NCBI chr18:71,386,703...72,484,299
Ensembl chr18:71,386,705...72,484,140
JBrowse link
G Dnd1 DND microRNA-mediated repression inhibitor 1 IAGP MGI PMID:23773267 NCBI chr18:36,896,724...36,899,267
Ensembl chr18:36,896,724...36,899,267
JBrowse link
G Dnmt1 DNA methyltransferase 1 IAGP MGI PMID:11940649 NCBI chr 9:20,818,501...20,871,084
Ensembl chr 9:20,818,505...20,871,184
JBrowse link
G Ereg epiregulin IAGP MGI PMID:15456865 NCBI chr 5:91,222,476...91,241,508
Ensembl chr 5:91,222,481...91,241,505
JBrowse link
G Glp2r glucagon-like peptide 2 receptor IAGP MGI PMID:18829546 NCBI chr11:67,554,877...67,661,979
Ensembl chr11:67,552,328...67,661,979
JBrowse link
G Gpa33 glycoprotein A33 transmembrane IAGP MGI PMID:20531296 NCBI chr 1:165,957,790...165,994,079
Ensembl chr 1:165,957,807...165,994,079
JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:18056424 PMID:19251594 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,054,294
JBrowse link
G Helq helicase, POLQ-like IAGP MGI PMID:24005329 NCBI chr 5:100,910,010...100,946,529
Ensembl chr 5:100,910,011...100,946,464
JBrowse link
G Hpgds hematopoietic prostaglandin D synthase IAGP MGI PMID:17283118 NCBI chr 6:65,094,019...65,121,960
Ensembl chr 6:65,094,277...65,121,892
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 IAGP MGI PMID:20531296 NCBI chr  X:52,076,955...52,110,537
Ensembl chr  X:52,077,014...52,110,536
JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 IAGP MGI PMID:23741059 NCBI chr 8:106,245,378...106,250,620
Ensembl chr 8:106,245,387...106,250,620
JBrowse link
G Il22ra2 interleukin 22 receptor, alpha 2 IAGP MGI PMID:23075849 NCBI chr10:19,497,776...19,510,429
Ensembl chr10:19,497,746...19,510,429
JBrowse link
G Krt19 keratin 19 IAGP MGI PMID:10545105 NCBI chr11:100,031,636...100,036,752
Ensembl chr11:100,031,636...100,039,491
JBrowse link
G Lgr5 leucine rich repeat containing G protein coupled receptor 5 IAGP MGI PMID:22464327 PMID:22895187 PMID:26527802 NCBI chr10:115,286,219...115,423,685
Ensembl chr10:115,286,216...115,423,685
JBrowse link
G Lrig1 leucine-rich repeats and immunoglobulin-like domains 1 IAGP MGI PMID:22464327 NCBI chr 6:94,581,510...94,677,205
Ensembl chr 6:94,581,510...94,677,139
JBrowse link
G Mapkapk2 MAP kinase-activated protein kinase 2 IAGP MGI PMID:29844172 NCBI chr 1:130,981,437...131,025,580
Ensembl chr 1:130,981,437...131,025,563
JBrowse link
G Mbd4 methyl-CpG binding domain protein 4 IAGP MGI PMID:12130785 NCBI chr 6:115,817,658...115,830,361
Ensembl chr 6:115,817,658...115,830,332
JBrowse link
G Men1 multiple endocrine neoplasia 1 IAGP MGI PMID:12819299 NCBI chr19:6,385,009...6,390,924
Ensembl chr19:6,385,009...6,390,921
JBrowse link
G Mir10a microRNA 10a IAGP MGI PMID:24204315 NCBI chr11:96,207,991...96,208,100
Ensembl chr11:96,207,991...96,208,100
JBrowse link
G Mlh1 mutL homolog 1 IAGP MGI PMID:11940649 PMID:19805137 NCBI chr 9:111,057,296...111,100,854
Ensembl chr 9:111,057,296...111,100,859
JBrowse link
G Msh2 mutS homolog 2 IAGP MGI PMID:8674041 PMID:19931261 NCBI chr17:87,979,960...88,031,141
Ensembl chr17:87,979,758...88,031,141
JBrowse link
G Msh6 mutS homolog 6 IAGP MGI PMID:15324697 NCBI chr17:88,282,478...88,298,320
Ensembl chr17:88,282,490...88,298,320
JBrowse link
G Nf1 neurofibromin 1 IAGP MGI PMID:25119042 NCBI chr11:79,223,541...79,472,435
Ensembl chr11:79,230,519...79,472,438
JBrowse link
G Nuak2 NUAK family, SNF1-like kinase, 2 IAGP MGI PMID:18307533 NCBI chr 1:132,243,827...132,261,233
Ensembl chr 1:132,243,864...132,261,226
JBrowse link
G Pax6 paired box 6 IAGP MGI PMID:17660683 NCBI chr 2:105,499,241...105,528,755
Ensembl chr 2:105,499,245...105,527,709
JBrowse link
G Pms2 PMS1 homolog2, mismatch repair system component IAGP MGI PMID:9515784 NCBI chr 5:143,846,379...143,922,538
Ensembl chr 5:143,846,782...143,870,786
Ensembl chr 5:143,846,782...143,870,786
JBrowse link
G Pold1 polymerase (DNA directed), delta 1, catalytic subunit IAGP MGI PMID:19805137 NCBI chr 7:44,182,168...44,198,239
Ensembl chr 7:44,182,170...44,198,273
JBrowse link
G Pole polymerase (DNA directed), epsilon IAGP MGI PMID:19805137 NCBI chr 5:110,434,185...110,485,319
Ensembl chr 5:110,434,172...110,485,340
JBrowse link
G Ppard peroxisome proliferator activator receptor delta IAGP MGI PMID:11756685 NCBI chr17:28,451,715...28,520,446
Ensembl chr17:28,451,674...28,520,448
JBrowse link
G Pten phosphatase and tensin homolog IAGP MGI PMID:19168705 NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560
JBrowse link
G Ptgds prostaglandin D2 synthase (brain) IAGP MGI PMID:17283118 NCBI chr 2:25,356,723...25,360,080
Ensembl chr 2:25,356,721...25,360,058
JBrowse link
G Rab25 RAB25, member RAS oncogene family IAGP MGI PMID:20197623 NCBI chr 3:88,449,335...88,455,586
Ensembl chr 3:88,449,336...88,455,607
JBrowse link
G Rnf43 ring finger protein 43 IAGP MGI PMID:22895187 NCBI chr11:87,553,913...87,626,365
Ensembl chr11:87,553,548...87,626,365
JBrowse link
G Smad2 SMAD family member 2 IAGP MGI PMID:12384562 NCBI chr18:76,369,898...76,444,819
Ensembl chr18:76,374,651...76,444,034
JBrowse link
G Smad4 SMAD family member 4 IAGP MGI PMID:12557227 PMID:16288217 NCBI chr18:73,767,861...73,836,862
Ensembl chr18:73,772,080...73,836,851
JBrowse link
G Spata18 spermatogenesis associated 18 IAGP MGI PMID:26216032 NCBI chr 5:73,808,723...73,836,927
Ensembl chr 5:73,808,722...73,836,855
JBrowse link
G Stk11 serine/threonine kinase 11 IAGP MGI PMID:12060709 NCBI chr10:79,951,602...79,966,513
Ensembl chr10:79,951,637...79,966,516
JBrowse link
G Suz12 SUZ12 polycomb repressive complex 2 subunit IAGP MGI PMID:25119042 NCBI chr11:79,883,932...79,924,949
Ensembl chr11:79,883,932...79,924,949
JBrowse link
G Tcf7 transcription factor 7, T cell specific IAGP MGI PMID:10489374 NCBI chr11:52,137,347...52,174,211
Ensembl chr11:52,143,198...52,174,158
JBrowse link
G Tcf7l2 transcription factor 7 like 2, T cell specific, HMG box IAGP MGI PMID:21383188 NCBI chr19:55,730,227...55,922,091
Ensembl chr19:55,730,252...55,922,086
JBrowse link
G Thbs1 thrombospondin 1 IAGP MGI PMID:12584168 NCBI chr 2:117,942,357...117,957,614
Ensembl chr 2:117,942,357...117,957,614
JBrowse link
G Tmigd1 transmembrane and immunoglobulin domain containing 1 IAGP MGI PMID:33129760 NCBI chr11:76,781,946...76,807,413
Ensembl chr11:76,792,985...76,807,413
JBrowse link
G Tnk1 tyrosine kinase, non-receptor, 1 IAGP MGI PMID:18974114 NCBI chr11:69,741,389...69,749,556
Ensembl chr11:69,741,831...69,749,556
JBrowse link
G Tpx2 TPX2, microtubule-associated IAGP MGI PMID:22266221 NCBI chr 2:152,689,859...152,737,241
Ensembl chr 2:152,689,884...152,737,241
JBrowse link
G Trp53 transformation related protein 53 IAGP MGI PMID:21411755 PMID:32728212 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link
G Zbtb33 zinc finger and BTB domain containing 33 IAGP MGI PMID:16354691 NCBI chr  X:37,278,670...37,285,923
Ensembl chr  X:37,278,670...37,285,923
JBrowse link
G Znrf3 zinc and ring finger 3 IAGP MGI PMID:22895187 NCBI chr11:5,226,329...5,394,847
Ensembl chr11:5,226,324...5,394,847
JBrowse link
increased colon adenoma incidence term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC, WNT signaling pathway regulator IAGP MGI PMID:9311916 PMID:12242442 PMID:15502862 PMID:15650110 PMID:15703196 More... NCBI chr18:34,353,350...34,455,243
Ensembl chr18:34,353,977...34,455,605
JBrowse link
G Blm Bloom syndrome, RecQ like helicase IAGP MGI PMID:12242442 NCBI chr 7:80,104,839...80,184,896
Ensembl chr 7:80,104,481...80,184,867
JBrowse link
G Bub1b BUB1B, mitotic checkpoint serine/threonine kinase IAGP MGI PMID:14744753 NCBI chr 2:118,428,684...118,472,073
Ensembl chr 2:118,428,692...118,472,072
JBrowse link
G Ccdc80 coiled-coil domain containing 80 IAGP MGI PMID:25053805 NCBI chr16:44,913,770...44,948,287
Ensembl chr16:44,913,765...44,948,440
JBrowse link
G Cdx2 caudal type homeobox 2 IAGP MGI PMID:9052785 NCBI chr 5:147,237,710...147,244,059
Ensembl chr 5:147,237,615...147,244,080
JBrowse link
G Elavl1 ELAV like RNA binding protein 1 IAGP MGI PMID:22201685 NCBI chr 8:4,334,781...4,375,104
Ensembl chr 8:4,335,382...4,375,413
JBrowse link
G Esr1 estrogen receptor 1 (alpha) IAGP MGI PMID:17332369 NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614
JBrowse link
G Esr2 estrogen receptor 2 (beta) IAGP MGI PMID:17332369 NCBI chr12:76,167,193...76,224,033
Ensembl chr12:76,167,193...76,224,033
JBrowse link
G Foxl1 forkhead box L1 IAGP MGI PMID:15650110 NCBI chr 8:121,854,572...121,857,383
Ensembl chr 8:121,854,679...121,857,383
JBrowse link
G Fpr2 formyl peptide receptor 2 IAGP MGI PMID:23454745 NCBI chr17:18,108,086...18,114,214
Ensembl chr17:18,108,086...18,114,214
JBrowse link
G Kras Kirsten rat sarcoma viral oncogene homolog IAGP MGI PMID:20080688 PMID:30952657 NCBI chr 6:145,162,425...145,197,631
Ensembl chr 6:145,162,425...145,195,965
JBrowse link
G Lyz2 lysozyme 2 IAGP MGI PMID:22201685 NCBI chr10:117,113,446...117,118,177
Ensembl chr10:117,113,236...117,118,226
JBrowse link
G Mir708 microRNA 708 IAGP MGI PMID:34934045 NCBI chr 7:95,898,631...95,898,739
Ensembl chr 7:95,898,631...95,898,739
JBrowse link
G Ptprt protein tyrosine phosphatase receptor type T IAGP MGI PMID:20133777 NCBI chr 2:161,363,908...162,503,106
Ensembl chr 2:161,363,910...162,503,067
JBrowse link
G Rab25 RAB25, member RAS oncogene family IAGP MGI PMID:20197623 NCBI chr 3:88,449,335...88,455,586
Ensembl chr 3:88,449,336...88,455,607
JBrowse link
G Rasal2 RAS protein activator like 2 IAGP MGI PMID:24029233 NCBI chr 1:156,962,759...157,240,170
Ensembl chr 1:156,962,752...157,240,165
JBrowse link
G Rb1 RB transcriptional corepressor 1 IAGP MGI PMID:16227443 NCBI chr14:73,430,298...73,563,446
Ensembl chr14:73,421,113...73,563,262
JBrowse link
G Recql4 RecQ protein-like 4 IAGP MGI PMID:15703196 NCBI chr15:76,587,753...76,594,820
Ensembl chr15:76,587,753...76,594,748
JBrowse link
G Slc5a8 solute carrier family 5 (iodide transporter), member 8 IAGP MGI PMID:18562324 NCBI chr10:88,721,854...88,765,377
Ensembl chr10:88,721,854...88,765,377
JBrowse link
G Spata18 spermatogenesis associated 18 IAGP MGI PMID:26216032 NCBI chr 5:73,808,723...73,836,927
Ensembl chr 5:73,808,722...73,836,855
JBrowse link
G Tlr2 toll-like receptor 2 IAGP MGI PMID:20885960 NCBI chr 3:83,743,579...83,749,045
Ensembl chr 3:83,743,579...83,749,074
JBrowse link
G Trp53 transformation related protein 53 IAGP MGI PMID:16227443 PMID:24029233 PMID:32728212 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link
G Trp53inp1 transformation related protein 53 inducible nuclear protein 1 IAGP MGI PMID:17242209 NCBI chr 4:11,156,441...11,174,379
Ensembl chr 4:11,156,431...11,174,379
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16734
    digestive/alimentary phenotype 1890
      abnormal digestive system morphology 1498
        increased alimentary system tumor incidence 165
          increased gastrointestinal tumor incidence 149
            increased intestinal adenoma incidence 82
              increased colon adenoma incidence 29
Path 2
Term Annotations click to browse term
  mammalian phenotype 16734
    neoplasm 1342
      abnormal tumor susceptibility 1202
        abnormal tumor incidence 1181
          abnormal organ/body region tumor incidence 892
            increased organ/body region tumor incidence 849
              increased alimentary system tumor incidence 165
                increased gastrointestinal tumor incidence 149
                  increased intestinal adenoma incidence 82
                    increased colon adenoma incidence 29
paths to the root