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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal respiratory system morphology
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Accession:MP:0002132 term browser browse the term
Definition:any structural anomaly of pulmonary tissues
Synonyms:exact_synonym: respiratory system: dysmorphology
 narrow_synonym: pulmonary malformation;   respiratory system dysplasia
 alt_id: MP:0001174
 xref: Fyler:4235;   MGI:2173592



show annotations for term's descendants           Sort by:
abnormal nasal mucosa morphology term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cftr CF transmembrane conductance regulator IMP RGD PMID:24608905 RGD:11566051 NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:46,560,885...46,728,756
JBrowse link
G Cftrem1Sage cystic fibrosis transmembrane conductance regulator; ZFN induced mutant 1 Sage IMP RGD PMID:24608905 RGD:11566051
abnormal nose morphology term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pax6 paired box 6 IAGP RGD PMID:7981749 RGD:1601213 NCBI chr 3:112,590,034...112,611,771
Ensembl chr 3:92,135,637...92,157,014
JBrowse link
G Pax6Sey paired box gene 6, small eye mutation IAGP RGD PMID:7981749 RGD:1601213
abnormal pulmonary collagen fibril morphology term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnk3 potassium two pore domain channel subfamily K member 3 IMP RGD PMID:31347976 RGD:151347452 NCBI chr 6:31,483,129...31,519,061
Ensembl chr 6:25,763,228...25,799,153
JBrowse link
G Kcnk3em1Ang potassium two pore domain channel subfamily K member 3; CRISPR/Cas9 induced mutant1, Ang IMP RGD PMID:31347976 RGD:151347452
abnormal trachea gland morphology term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cftr CF transmembrane conductance regulator IMP RGD PMID:24608905 RGD:11566051 NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:46,560,885...46,728,756
JBrowse link
G Cftrem1Sage cystic fibrosis transmembrane conductance regulator; ZFN induced mutant 1 Sage IMP RGD PMID:24608905 RGD:11566051
abnormal trachea morphology term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arsb arylsulfatase B IAGP RGD PMID:21887218 RGD:39131283 NCBI chr 2:26,736,395...26,895,682
Ensembl chr 2:25,002,346...25,162,671
JBrowse link
abnormal tracheal cartilage morphology term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cftr CF transmembrane conductance regulator IMP RGD PMID:24608905 RGD:11566051 NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:46,560,885...46,728,756
JBrowse link
G Cftrem1Sage cystic fibrosis transmembrane conductance regulator; ZFN induced mutant 1 Sage IMP RGD PMID:24608905 RGD:11566051
dilated respiratory conducting tube term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rab38 RAB38, member RAS oncogene family IAGP RGD PMID:19897744 RGD:2324690 NCBI chr 1:151,595,153...151,675,492
Ensembl chr 1:142,182,556...142,262,924
JBrowse link
G Rab38ru Rab38, member of RAS oncogene family, ruby allele IAGP RGD PMID:19897744 RGD:2324690
enlarged alveolar lamellar bodies term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrrk2 leucine-rich repeat kinase 2 IMP RGD PMID:24465451 RGD:13462051 NCBI chr 7:124,706,246...124,867,234
Ensembl chr 7:122,826,696...122,987,703
JBrowse link
G Lrrk2em1Sage leucine-rich repeat kinase 2; zinc finger nuclease induced mutant 1, Sigma Advanced Genetic Engineering Labs IMP RGD PMID:24465451 RGD:13462051
G Rab38 RAB38, member RAS oncogene family IMP RGD PMID:28438206 RGD:13524861 NCBI chr 1:151,595,153...151,675,492
Ensembl chr 1:142,182,556...142,262,924
JBrowse link
G Rab38ru Rab38, member of RAS oncogene family, ruby allele IMP RGD PMID:28438206 RGD:13524861
fused right lung lobes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Frem2 FRAS1 related extracellular matrix 2 IAGP RGD PMID:21756877 RGD:13464328 NCBI chr 2:139,753,055...139,891,046
Ensembl chr 2:137,602,784...137,740,785
JBrowse link
G Frem2fpl Fras1 related extracellular matrix protein 2;fpl mutant IAGP RGD PMID:21756877 RGD:13464328
increased alveolar lamellar body number term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrrk2 leucine-rich repeat kinase 2 IMP RGD PMID:24244710 RGD:12880447 NCBI chr 7:124,706,246...124,867,234
Ensembl chr 7:122,826,696...122,987,703
JBrowse link
G Lrrk2em1Sage leucine-rich repeat kinase 2; zinc finger nuclease induced mutant 1, Sigma Advanced Genetic Engineering Labs IMP RGD PMID:24244710 RGD:12880447
increased lung weight term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdkn1b cyclin-dependent kinase inhibitor 1B IMP in KO rat RGD PMID:30893315 RGD:126908018 NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Cdkn1bem1Musc cyclin-dependent kinase inhibitor 1B; CRISPR/Cas9 induced mutant 1, Musc IMP RGD PMID:30893315 RGD:126908018
G Cdkn1bem4Musc cyclin-dependent kinase inhibitor 1B; CRISPR/Cas9 induced mutant 4, Musc IMP RGD PMID:30893315 RGD:126908018
pulmonary fibrosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddah1 dimethylarginine dimethylaminohydrolase 1 induces IMP compared to wild type RGD PMID:31402164 RGD:151347602 NCBI chr 2:237,327,812...237,460,624
Ensembl chr 2:234,667,491...234,799,339
JBrowse link
G Ddah1em1Ywxu dimethylarginine dimethylaminohydrolase 1; CRISPR/Cas9 induced mutant 1, Ywxu induces IMP compared to wild type RGD PMID:31402164 RGD:151347602
pulmonary vascular congestion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lepr leptin receptor treatment IAGP RGD PMID:33568522 RGD:401965412 NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:116,289,823...116,475,908
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5421
    respiratory system phenotype 47
      abnormal respiratory system morphology 33
        abnormal larynx morphology + 0
        abnormal lung morphology + 26
        abnormal nose morphology + 5
        abnormal paranasal sinus morphology + 0
        abnormal pharynx morphology + 0
        abnormal pleura morphology + 0
        abnormal pleural cavity morphology 0
        abnormal respiratory epithelium morphology + 9
        abnormal respiratory system development + 0
        abnormal respiratory tract brush cell morphology 0
        abnormal sputum morphology + 0
        abnormal trachea morphology + 5
        decreased respiratory system tumor incidence + 0
        increased respiratory system tumor incidence + 0
paths to the root