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ONTOLOGY REPORT - ANNOTATIONS


Term:increased thermal nociceptive threshold
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Accession:MP:0001973 term browser browse the term
Definition:a greater than average point at which thermal pain sensation is first detectable
Synonyms:exact_synonym: decreased thermal nociception;   prolonged latency in hot plate test;   thermal hypoalgesia


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increased thermal nociceptive threshold term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G 9430015G10Rik RIKEN cDNA 9430015G10 gene JBrowse link 4 156,109,998 156,127,265 RGD:5509061
G Abcc4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 JBrowse link 14 118,482,692 118,707,856 RGD:5509061
G Adora2a adenosine A2a receptor JBrowse link 10 75,316,877 75,334,792 RGD:5509061
G Arid1b AT rich interactive domain 1B (SWI-like) JBrowse link 17 4,994,297 5,347,656 RGD:5509061
G Atp1a3 ATPase, Na+/K+ transporting, alpha 3 polypeptide JBrowse link 7 24,978,165 25,006,077 RGD:5509061
G Avil advillin JBrowse link 10 127,000,065 127,020,994 RGD:5509061
G Bambi BMP and activin membrane-bound inhibitor JBrowse link 18 3,507,011 3,516,404 RGD:5509061
G Cacna1b calcium channel, voltage-dependent, N type, alpha 1B subunit JBrowse link 2 24,603,860 24,763,200 RGD:5509061
G Cacna2d3 calcium channel, voltage-dependent, alpha2/delta subunit 3 JBrowse link 14 28,904,943 29,722,775 RGD:5509061
G Capn7 calpain 7 JBrowse link 14 31,336,622 31,371,987 RGD:5509061
G Cdca8 cell division cycle associated 8 JBrowse link 4 124,918,465 124,936,917 RGD:5509061
G Clcn6 chloride channel, voltage-sensitive 6 JBrowse link 4 148,004,259 148,038,813 RGD:5509061
G Cnr1 cannabinoid receptor 1 (brain) JBrowse link 4 33,923,171 33,948,831 RGD:5509061
G Ctsc cathepsin C JBrowse link 7 88,278,024 88,315,861 RGD:5509061
G Dhtkd1 dehydrogenase E1 and transketolase domain containing 1 JBrowse link 2 5,896,219 5,942,829 RGD:5509061
G Elp1 elongator complex protein 1 JBrowse link 4 56,746,547 56,802,569 RGD:5509061
G Faah fatty acid amide hydrolase JBrowse link 4 115,996,668 116,018,837 RGD:5509061
G Fmr1 fragile X mental retardation 1 JBrowse link X 68,678,536 68,717,963 RGD:5509061
G Frzb frizzled-related protein JBrowse link 2 80,411,970 80,447,396 RGD:5509061
G Fxr2 fragile X mental retardation, autosomal homolog 2 JBrowse link 11 69,632,971 69,653,297 RGD:5509061
G Galr2 galanin receptor 2 JBrowse link 11 116,280,106 116,283,950 RGD:5509061
G Gbx1 gastrulation brain homeobox 1 JBrowse link 5 24,504,426 24,526,848 RGD:5509061
G Git2 GIT ArfGAP 2 JBrowse link 5 114,727,408 114,774,588 RGD:5509061
G Gpr3 G-protein coupled receptor 3 JBrowse link 4 133,209,340 133,212,536 RGD:5509061
G Gria3 glutamate receptor, ionotropic, AMPA3 (alpha 3) JBrowse link X 41,400,854 41,678,601 RGD:5509061
G Gria4 glutamate receptor, ionotropic, AMPA4 (alpha 4) JBrowse link 9 4,417,893 4,796,234 RGD:5509061
G Grik5 glutamate receptor, ionotropic, kainate 5 (gamma 2) JBrowse link 7 25,009,849 25,075,694 RGD:5509061
G Grk5 G protein-coupled receptor kinase 5 JBrowse link 19 60,889,560 61,095,968 RGD:5509061
G Grm5 glutamate receptor, metabotropic 5 JBrowse link 7 87,583,981 88,135,063 RGD:5509061
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano JBrowse link 6 113,067,428 113,077,244 RGD:5509061
G Hcn2 hyperpolarization-activated, cyclic nucleotide-gated K+ 2 JBrowse link 10 79,716,634 79,736,108 RGD:5509061
G Hdac4 histone deacetylase 4 JBrowse link 1 91,928,779 92,195,702 RGD:5509061
G Hdc histidine decarboxylase JBrowse link 2 126,593,659 126,624,025 RGD:5509061
G Hivep2 human immunodeficiency virus type I enhancer binding protein 2 JBrowse link 10 13,961,609 14,151,378 RGD:5509061
G Hmgn3 high mobility group nucleosomal binding domain 3 JBrowse link 9 83,109,942 83,147,358 RGD:5509061
G Hoxb8 homeobox B8 JBrowse link 11 96,279,401 96,285,325 RGD:5509061
G Hoxc8 homeobox C8 JBrowse link 15 102,990,539 102,994,275 RGD:5509061
G Hoxd1 homeobox D1 JBrowse link 2 74,762,980 74,765,142 RGD:5509061
G Htr1f 5-hydroxytryptamine (serotonin) receptor 1F JBrowse link 16 64,924,729 65,105,784 RGD:5509061
G Htr7 5-hydroxytryptamine (serotonin) receptor 7 JBrowse link 19 35,958,415 36,058,133 RGD:5509061
G Il10 interleukin 10 JBrowse link 1 131,019,845 131,024,970 RGD:5509061
G Ireb2 iron responsive element binding protein 2 JBrowse link 9 54,862,658 54,912,534 RGD:5509061
G Kcna6 potassium voltage-gated channel, shaker-related, subfamily, member 6 JBrowse link 6 126,708,328 126,740,834 RGD:5509061
G Kcnip3 Kv channel interacting protein 3, calsenilin JBrowse link 2 127,456,498 127,522,094 RGD:5509061
G Kmt5b lysine methyltransferase 5B JBrowse link 19 3,767,362 3,818,303 RGD:5509061
G Lep leptin JBrowse link 6 29,060,221 29,073,876 RGD:5509061
G Lgals1 lectin, galactose binding, soluble 1 JBrowse link 15 78,926,725 78,930,465 RGD:5509061
G Lpar5 lysophosphatidic acid receptor 5 JBrowse link 6 125,067,844 125,086,129 RGD:5509061
G Lxn latexin JBrowse link 3 67,457,999 67,463,907 RGD:5509061
G Mcph1 microcephaly, primary autosomal recessive 1 JBrowse link 8 18,595,116 18,808,089 RGD:5509061
G Mecp2 methyl CpG binding protein 2 JBrowse link X 74,026,592 74,085,690 RGD:5509061
G Mgll monoglyceride lipase JBrowse link 6 88,724,412 88,828,360 RGD:5509061
G Mrgprd MAS-related GPR, member D JBrowse link 7 145,314,835 145,324,059 RGD:5509061
G Nav2 neuron navigator 2 JBrowse link 7 48,959,063 49,610,090 RGD:5509061
G Ndn necdin JBrowse link 7 62,348,277 62,349,928 RGD:5509061
G Nf2 neurofibromin 2 JBrowse link 11 4,757,639 4,849,544 RGD:5509061
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 JBrowse link 3 135,584,655 135,691,969 RGD:5509061
G Nr2c2 nuclear receptor subfamily 2, group C, member 2 JBrowse link 6 92,091,418 92,173,058 RGD:5509061
G Ntrk1 neurotrophic tyrosine kinase, receptor, type 1 JBrowse link 3 87,778,244 87,795,242 RGD:5509061
G Ntsr2 neurotensin receptor 2 JBrowse link 12 16,653,443 16,660,236 RGD:5509061
G P2rx3 purinergic receptor P2X, ligand-gated ion channel, 3 JBrowse link 2 84,996,549 85,037,108 RGD:5509061
G P2rx6 purinergic receptor P2X, ligand-gated ion channel, 6 JBrowse link 16 17,561,867 17,572,015 RGD:5509061
G Pax3 paired box 3 JBrowse link 1 78,101,267 78,197,136 RGD:5509061
G Pcsk2 proprotein convertase subtilisin/kexin type 2 JBrowse link 2 143,546,133 143,816,284 RGD:5509061
G Pirt phosphoinositide-interacting regulator of transient receptor potential channels JBrowse link 11 66,911,905 66,929,877 RGD:5509061
G Ppm1f protein phosphatase 1F (PP2C domain containing) JBrowse link 16 16,896,469 16,927,375 RGD:5509061
G Prkar1b protein kinase, cAMP dependent regulatory, type I beta JBrowse link 5 139,017,304 139,150,703 RGD:5509061
G Prlhr prolactin releasing hormone receptor JBrowse link 19 60,465,641 60,468,933 RGD:5509061
G Prokr1 prokineticin receptor 1 JBrowse link 6 87,578,586 87,590,762 RGD:5509061
G Prrxl1 paired related homeobox protein-like 1 JBrowse link 14 32,595,867 32,649,246 RGD:5509061
G Ptgs1 prostaglandin-endoperoxide synthase 1 JBrowse link 2 36,216,742 36,258,593 RGD:5509061
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 1 150,100,031 150,108,234 RGD:5509061
G Ptprz1 protein tyrosine phosphatase, receptor type Z, polypeptide 1 JBrowse link 6 22,875,315 23,052,916 RGD:5509061
G Rab18 RAB18, member RAS oncogene family JBrowse link 18 6,765,167 6,791,606 RGD:5509061
G Rac3 Rac family small GTPase 3 JBrowse link 11 120,721,468 120,723,969 RGD:5509061
G Rapgefl1 Rap guanine nucleotide exchange factor (GEF)-like 1 JBrowse link 11 98,836,785 98,853,009 RGD:5509061
G Rars arginyl-tRNA synthetase JBrowse link 11 35,808,381 35,834,528 RGD:5509061
G Retreg1 reticulophagy regulator 1 JBrowse link 15 25,843,298 25,973,696 RGD:5509061
G Rnf170 ring finger protein 170 JBrowse link 8 26,119,368 26,143,875 RGD:5509061
G Scn10a sodium channel, voltage-gated, type X, alpha JBrowse link 9 119,608,456 119,719,322 RGD:5509061
G Scn9a sodium channel, voltage-gated, type IX, alpha JBrowse link 2 66,480,080 66,635,114 RGD:5509061
G Slc12a5 solute carrier family 12, member 5 JBrowse link 2 164,960,846 164,999,731 RGD:5509061
G Slc17a6 solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6 JBrowse link 7 51,621,830 51,671,126 RGD:5509061
G Slc33a1 solute carrier family 33 (acetyl-CoA transporter), member 1 JBrowse link 3 63,942,323 63,964,733 RGD:5509061
G Slc6a2 solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 JBrowse link 8 92,960,470 93,001,667 RGD:5509061
G Smc6 structural maintenance of chromosomes 6 JBrowse link 12 11,265,886 11,319,785 RGD:5509061
G Sod1 superoxide dismutase 1, soluble JBrowse link 16 90,220,762 90,226,333 RGD:5509061
G Th tyrosine hydroxylase JBrowse link 7 142,892,779 142,899,995 RGD:5509061
G Tlr4 toll-like receptor 4 JBrowse link 4 66,827,551 66,846,581 RGD:5509061
G Tpp1 tripeptidyl peptidase I JBrowse link 7 105,744,811 105,752,282 RGD:5509061
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 JBrowse link 1 14,872,644 14,918,862 RGD:5509061
G Trpc6 transient receptor potential cation channel, subfamily C, member 6 JBrowse link 9 8,543,867 8,680,752 RGD:5509061
G Trpm3 transient receptor potential cation channel, subfamily M, member 3 JBrowse link 19 22,137,797 22,995,410 RGD:5509061
G Trpm8 transient receptor potential cation channel, subfamily M, member 8 JBrowse link 1 88,306,735 88,388,853 RGD:5509061
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 JBrowse link 11 73,234,149 73,261,322 RGD:5509061
G Trpv3 transient receptor potential cation channel, subfamily V, member 3 JBrowse link 11 73,267,489 73,300,368 RGD:5509061
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 JBrowse link 5 114,622,152 114,658,435 RGD:5509061
G Uchl1 ubiquitin carboxy-terminal hydrolase L1 JBrowse link 5 66,676,121 66,687,234 RGD:5509061
G Ucp2 uncoupling protein 2 (mitochondrial, proton carrier) JBrowse link 7 100,493,337 100,499,629 RGD:5509061
G Whrn whirlin JBrowse link 4 63,414,908 63,496,083 RGD:5509061
G Zfp106 zinc finger protein 106 JBrowse link 2 120,506,820 120,563,864 RGD:5509061

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 13565
    integument phenotype 2150
      abnormal touch/ nociception 313
        abnormal thermal nociception 154
          increased thermal nociceptive threshold 101
Path 2
Term Annotations click to browse term
  mammalian phenotype 13565
    behavior/neurological phenotype 4100
      abnormal behavior 4088
        abnormal sensory capabilities/reflexes/nociception 1136
          abnormal touch/ nociception 313
            abnormal pain threshold 255
              hypoalgesia 162
                increased thermal nociceptive threshold 101
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.