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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:increased thermal nociceptive threshold
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Accession:MP:0001973 term browser browse the term
Definition:a greater than average point at which thermal pain sensation is first detectable
Synonyms:exact_synonym: decreased thermal nociception;   prolonged latency in hot plate test;   thermal hypoalgesia


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increased thermal nociceptive threshold term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bace1 beta-secretase 1 IMP RGD PMID:28281673 RGD:13782149 NCBI chr 8:46,142,060...46,166,268
Ensembl chr 8:46,142,116...46,165,876 		JBrowse link
G Bace1em1Sage IMP RGD PMID:28281673 RGD:13782149
G Fcgr1a Fc gamma receptor 1A IMP RGD PMID:32510872 RGD:127338469 NCBI chr 2:183,851,075...183,860,077
Ensembl chr 2:183,851,077...183,859,994 		JBrowse link
G Grm2 glutamate metabotropic receptor 2 IMP knock-out compared to wild-type rats RGD PMID:30283001 RGD:38501063 NCBI chr 8:107,280,099...107,293,159
Ensembl chr 8:107,280,099...107,293,146 		JBrowse link
G Grm2em1 glutamate metabotropic receptor 2; endonuclease induced mutant 1 IMP KO compared to wild-type rats RGD PMID:30283001 RGD:38501063
G Prkar1b protein kinase cAMP-dependent type I regulatory subunit beta IMP RGD PMID:33479380 RGD:150519900 NCBI chr12:15,492,233...15,624,942
Ensembl chr12:15,511,801...15,624,942 		JBrowse link
G Prkar1bem2Tua protein kinase cAMP-dependent type I regulatory subunit beta; CRISPR/Cas9 induced mutant 2, Tua IMP RGD PMID:33479380 RGD:150519900
G Scn9a sodium voltage-gated channel alpha subunit 9 induces IMP RGD PMID:31550995 RGD:150429745 NCBI chr 3:51,145,148...51,293,342
Ensembl chr 3:51,145,146...51,293,516 		JBrowse link
G Scn9a*tm1Amgn sodium voltage-gated channel alpha subunit 9;ZFN induced target mutant1, Amgn induces IMP RGD PMID:31550995 RGD:150429745
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5402
    behavior/neurological phenotype 595
      abnormal behavior 594
        abnormal sensory capabilities/reflexes/nociception 78
          abnormal touch/ nociception 38
            abnormal thermal nociception 18
              increased thermal nociceptive threshold 16
Path 2
Term Annotations click to browse term
  mammalian phenotype 5402
    behavior/neurological phenotype 595
      abnormal behavior 594
        abnormal sensory capabilities/reflexes/nociception 78
          abnormal touch/ nociception 38
            abnormal pain threshold 32
              hypoalgesia 22
                increased thermal nociceptive threshold 16
paths to the root