Send us a Message

Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   


The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories ( For more information about these ontologies, see the MGI Publications Page at

Term:abnormal humoral immune response
go back to main search page
Accession:MP:0001800 term browser browse the term
Definition:any functional anomaly of the aspect of immunity that is mediated by secreted antibodies produced in the cells of the B lymphocyte lineage (B cell) and the accessory processes that accompany it, including Th2 activation and cytokine production, germinal center formation and isotype switching, affinity maturation and memory cell generation; it also refers to the effector functions of antibody, which include pathogen and toxin neutralization, classical complement activation, and opsonin promotion of phagocytosis and pathogen elimination
Synonyms:exact_synonym: abnormal humoural immune response;   antibody-mediated immune response abnormalities;   humoral immune response dysfunction;   humoural immune response dysfunction

GViewer not supported for the selected species.

show annotations for term's descendants           Sort by:

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 0
    immune system phenotype 0
      abnormal immune system physiology 0
        abnormal humoral immune response 0
          abnormal complement pathway + 0
          abnormal immunoglobulin level + 0
          enhanced humoral immune response 0
          impaired humoral immune response 0
paths to the root