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ONTOLOGY REPORT - ANNOTATIONS


Term:abnormal mesoderm development
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Accession:MP:0001680 term browser browse the term
Definition:failure or abnormality in the formation of the middle of the three primary germ layers of the embryo (the others being ectoderm and endoderm) during gastrulation; mesoderm is the origin of connective tissues, myoblasts, blood, the cardiovascular and lymphatic systems, most of the urogenital system, and the lining of the pericardial, pleural, and peritoneal cavities
Synonyms:exact_synonym: abnormal mesoderm differentiation
 alt_id: MP:0001681
 xref: GO:0001707


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abnormal mesoderm development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acvr1 activin A receptor, type 1 JBrowse link 2 58,446,438 58,566,828 RGD:5509061
G Acvr2b activin receptor IIB JBrowse link 9 119,401,583 119,442,148 RGD:5509061
G Afdn afadin, adherens junction formation factor JBrowse link 17 13,760,391 13,905,798 RGD:5509061
G Amn amnionless JBrowse link 12 111,271,096 111,276,426 RGD:5509061
G Bmp4 bone morphogenetic protein 4 JBrowse link 14 46,383,525 46,390,669 RGD:5509061
G Cdx2 caudal type homeobox 2 JBrowse link 5 147,300,900 147,307,249 RGD:5509061
G Chd1 chromodomain helicase DNA binding protein 1 JBrowse link 17 15,704,967 15,772,612 RGD:5509061
G Chrd chordin JBrowse link 16 20,731,425 20,742,384 RGD:5509061
G Cstf2 cleavage stimulation factor, 3' pre-RNA subunit 2 JBrowse link X 134,059,176 134,086,822 RGD:5509061
G Dad1 defender against cell death 1 JBrowse link 14 54,235,485 54,253,929 RGD:5509061
G Drap1 Dr1 associated protein 1 (negative cofactor 2 alpha) JBrowse link 19 5,422,804 5,424,979 RGD:5509061
G Ecsit ECSIT signalling integrator JBrowse link 9 22,071,435 22,086,296 RGD:5509061
G Edil3 EGF-like repeats and discoidin I-like domains 3 JBrowse link 13 88,821,472 89,323,225 RGD:5509061
G Epb41l5 erythrocyte membrane protein band 4.1 like 5 JBrowse link 1 119,545,032 119,649,096 RGD:5509061
G Exoc4 exocyst complex component 4 JBrowse link 6 33,249,090 33,973,979 RGD:5509061
G Fgf8 fibroblast growth factor 8 JBrowse link 19 45,736,798 45,742,941 RGD:5509061
G Fgfr1 fibroblast growth factor receptor 1 JBrowse link 8 25,518,759 25,575,718 RGD:5509061
G Fn1 fibronectin 1 JBrowse link 1 71,585,473 71,653,280 RGD:5509061
G Gdf3 growth differentiation factor 3 JBrowse link 6 122,605,403 122,610,087 RGD:5509061
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano JBrowse link 6 113,067,428 113,077,244 RGD:5509061
G Hand1 heart and neural crest derivatives expressed 1 JBrowse link 11 57,828,713 57,832,147 RGD:5509061
G Kat2a K(lysine) acetyltransferase 2A JBrowse link 11 100,704,746 100,712,485 RGD:5509061
G Kif3a kinesin family member 3A JBrowse link 11 53,565,701 53,604,248 RGD:5509061
G Lrp5 low density lipoprotein receptor-related protein 5 JBrowse link 19 3,584,825 3,686,585 RGD:5509061
G Lrp6 low density lipoprotein receptor-related protein 6 JBrowse link 6 134,446,476 134,566,913 RGD:5509061
G Mesp1 mesoderm posterior 1 JBrowse link 7 79,792,241 79,793,590 RGD:5509061
G Mesp2 mesoderm posterior 2 JBrowse link 7 79,810,727 79,813,431 RGD:5509061
G Mtch2 mitochondrial carrier 2 JBrowse link 2 90,847,090 90,866,810 RGD:5509061
G Nckap1 NCK-associated protein 1 JBrowse link 2 80,500,512 80,581,182 RGD:5509061
G Nodal nodal JBrowse link 10 61,417,972 61,425,338 RGD:5509061
G Nr5a2 nuclear receptor subfamily 5, group A, member 2 JBrowse link 1 136,842,562 136,960,448 RGD:5509061
G Otx2 orthodenticle homeobox 2 JBrowse link 14 48,656,781 48,667,644 RGD:5509061
G Palb2 partner and localizer of BRCA2 JBrowse link 7 122,107,262 122,132,980 RGD:5509061
G Pitx2 paired-like homeodomain transcription factor 2 JBrowse link 3 129,199,878 129,219,594 RGD:5509061
G Poglut1 protein O-glucosyltransferase 1 JBrowse link 16 38,525,058 38,550,257 RGD:5509061
G Porcn porcupine O-acyltransferase JBrowse link X 8,193,846 8,206,548 RGD:5509061
G Prkci protein kinase C, iota JBrowse link 3 30,995,742 31,052,740 RGD:5509061
G Ptk2 PTK2 protein tyrosine kinase 2 JBrowse link 15 73,205,102 73,423,820 RGD:5509061
G Rac1 Rac family small GTPase 1 JBrowse link 5 143,505,481 143,528,031 RGD:5509061
G Rangap1 RAN GTPase activating protein 1 JBrowse link 15 81,704,248 81,730,798 RGD:5509061
G Rdh10 retinol dehydrogenase 10 (all-trans) JBrowse link 1 16,105,882 16,132,550 RGD:5509061
G Rnf2 ring finger protein 2 JBrowse link 1 151,469,398 151,500,991 RGD:5509061
G Sall4 spalt like transcription factor 4 JBrowse link 2 168,748,332 168,767,201 RGD:5509061
G Slc31a1 solute carrier family 31, member 1 JBrowse link 4 62,360,583 62,391,769 RGD:5509061
G Smad1 SMAD family member 1 JBrowse link 8 79,338,395 79,399,428 RGD:5509061
G Smad4 SMAD family member 4 JBrowse link 18 73,634,790 73,703,791 RGD:5509061
G Smad5 SMAD family member 5 JBrowse link 13 56,703,010 56,742,378 RGD:5509061
G Snai1 snail family zinc finger 1 JBrowse link 2 167,538,195 167,542,814 RGD:5509061
G Strip1 striatin interacting protein 1 JBrowse link 3 107,612,532 107,631,710 RGD:5509061
G Supt20 SPT20 SAGA complex component JBrowse link 3 54,692,760 54,728,763 RGD:5509061
G T brachyury, T-box transcription factor T JBrowse link 17 8,434,423 8,442,496 RGD:5509061
G Tbx6 T-box 6 JBrowse link 7 126,781,483 126,785,548 RGD:5509061
G Tdgf1 teratocarcinoma-derived growth factor 1 JBrowse link 9 110,939,608 110,946,158 RGD:5509061
G Tfap2c transcription factor AP-2, gamma JBrowse link 2 172,545,678 172,558,622 RGD:5509061
G Tgif1 TGFB-induced factor homeobox 1 JBrowse link 17 70,844,205 70,853,532 RGD:5509061
G Tgif2 TGFB-induced factor homeobox 2 JBrowse link 2 156,839,817 156,855,570 RGD:5509061
G Tpt1 tumor protein, translationally-controlled 1 JBrowse link 14 75,845,256 75,848,303 RGD:5509061
G Trim33 tripartite motif-containing 33 JBrowse link 3 103,279,293 103,358,770 RGD:5509061
G Tsix X (inactive)-specific transcript, opposite strand JBrowse link X 103,431,517 103,484,957 RGD:5509061
G Ugdh UDP-glucose dehydrogenase JBrowse link 5 65,413,207 65,435,842 RGD:5509061
G Uhrf1 ubiquitin-like, containing PHD and RING finger domains, 1 JBrowse link 17 56,303,337 56,323,486 RGD:5509061
G Vcl vinculin JBrowse link 14 20,929,383 21,033,676 RGD:5509061
G Vps41 VPS41 HOPS complex subunit JBrowse link 13 18,717,292 18,866,811 RGD:5509061
G Wasl Wiskott-Aldrich syndrome-like (human) JBrowse link 6 24,613,810 24,664,995 RGD:5509061
G Wnt3a wingless-type MMTV integration site family, member 3A JBrowse link 11 59,248,036 59,290,751 RGD:5509061
G Zic3 zinc finger protein of the cerebellum 3 JBrowse link X 58,030,628 58,036,630 RGD:5509061
abnormal mesendoderm development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apc APC, WNT signaling pathway regulator JBrowse link 18 34,220,297 34,322,190 RGD:5509061
G Chrd chordin JBrowse link 16 20,731,425 20,742,384 RGD:5509061
G Col2a1 collagen, type II, alpha 1 JBrowse link 15 97,975,602 98,004,724 RGD:5509061
G Dpy30 dpy-30, histone methyltransferase complex regulatory subunit JBrowse link 17 74,299,474 74,323,944 RGD:5509061
G Drap1 Dr1 associated protein 1 (negative cofactor 2 alpha) JBrowse link 19 5,422,804 5,424,979 RGD:5509061
G Edil3 EGF-like repeats and discoidin I-like domains 3 JBrowse link 13 88,821,472 89,323,225 RGD:5509061
G Foxa2 forkhead box A2 JBrowse link 2 148,042,877 148,046,969 RGD:5509061
G Foxh1 forkhead box H1 JBrowse link 15 76,667,829 76,671,614 RGD:5509061
G Gdf1 growth differentiation factor 1 JBrowse link 8 70,315,775 70,331,592 RGD:5509061
G Hira histone cell cycle regulator JBrowse link 16 18,876,750 18,970,309 RGD:5509061
G Nodal nodal JBrowse link 10 61,417,972 61,425,338 RGD:5509061
G Nog noggin JBrowse link 11 89,300,638 89,302,559 RGD:5509061
G Nsd1 nuclear receptor-binding SET-domain protein 1 JBrowse link 13 55,209,782 55,318,325 RGD:5509061
G Otx2 orthodenticle homeobox 2 JBrowse link 14 48,656,781 48,667,644 RGD:5509061
G Sall4 spalt like transcription factor 4 JBrowse link 2 168,748,332 168,767,201 RGD:5509061
G Smad3 SMAD family member 3 JBrowse link 9 63,646,766 63,757,994 RGD:5509061
G Tdgf1 teratocarcinoma-derived growth factor 1 JBrowse link 9 110,939,608 110,946,158 RGD:5509061
G Trim33 tripartite motif-containing 33 JBrowse link 3 103,279,293 103,358,770 RGD:5509061
G Zic2 zinc finger protein of the cerebellum 2 JBrowse link 14 122,475,384 122,480,328 RGD:5509061

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  mammalian phenotype 13565
    embryo phenotype 2004
      abnormal embryo development 1158
        abnormal developmental patterning 540
          abnormal gastrulation 418
            abnormal germ layer development 140
              abnormal mesoderm development 77
                abnormal mesendoderm development 19
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.