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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal heart rate
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Accession:MP:0001629 term browser browse the term
Definition:greater than or fewer than average resting heart beats per minute, usually measured by the number of times the heart ventricles contract per unit of time, usually per minute
Synonyms:alt_id: MP:0000305



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decreased heart rate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnj16 potassium inwardly-rectifying channel, subfamily J, member 16 IMP compared to SS/JrHsdMcwi RGD PMID:28931751 RGD:38500204 NCBI chr10:95,990,009...96,021,356
Ensembl chr10:95,960,725...96,021,702
JBrowse link
G Kcnj16em1Mcwi potassium inwardly-rectifying channel, subfamily J, member 16; zinc finger nuclease induced mutant 1, Medical College of Wisconsin IMP compared to SS/JrHsdMcwi RGD PMID:28931751 RGD:38500204
G Mc4r melanocortin 4 receptor IMP compared with WI-MC4r^m1Hubr RGD PMID:24400148 PMID:24400148 RGD:13825242, RGD:13825242 NCBI chr18:60,419,832...60,421,719
Ensembl chr18:60,419,832...60,421,719
JBrowse link
G Mc4rm1Hubr melanocortin 4 receptor; ENU induced mutation 1, Hubr IMP compared with WI-MC4r^m1Hubr RGD PMID:24400148 PMID:24400148 RGD:13825242, RGD:13825242
G Rarres2 retinoic acid receptor responder 2 sexual_dimorphism IMP compared to male wild-type RGD PMID:29906243 PMID:29906243 RGD:38596340, RGD:38596340 NCBI chr 4:77,522,549...77,525,733
Ensembl chr 4:77,522,535...77,525,556
JBrowse link
G Rarres2em1Msu retinoic acid receptor responder 2; CRISPR/Cas9 induced mutant 1, Msu sexual_dimorphism IMP compared to male wild-type RGD PMID:29906243 PMID:29906243 RGD:38596340, RGD:38596340
G Tnf tumor necrosis factor IAGP RGD PMID:9590569 RGD:1357163 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
increased heart rate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmal1 basic helix-loop-helix ARNT like 1 sexual_dimorphism IMP in female RGD PMID:32306766 RGD:155598602 NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231
JBrowse link
G Bmal1em1Mcwi basic helix-loop-helix ARNT like 1;CRISPR/Cas9 induced mutant 1,Mcwi sexual_dimorphism IMP in female RGD PMID:32306766 RGD:155598602
G Glp1r glucagon-like peptide 1 receptor IDA RGD PMID:12093887 RGD:625448 NCBI chr20:8,972,004...9,010,241
Ensembl chr20:8,972,004...9,010,241
JBrowse link
G Kcnk3 potassium two pore domain channel subfamily K member 3 IMP RGD PMID:31347976 RGD:151347452 NCBI chr 6:25,761,487...25,799,153
Ensembl chr 6:25,763,228...25,799,153
JBrowse link
G Kcnk3em1Ang potassium two pore domain channel subfamily K member 3; CRISPR/Cas9 induced mutant1, Ang IMP RGD PMID:31347976 RGD:151347452
G Ren renin IMP compared to wild type RGD PMID:21242461 RGD:7771614 NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489
JBrowse link
G Renem1Mcwi renin; zinc finger nuclease induced mutant 1, Medical College of Wisconsin IMP compared to wild type RGD PMID:21242461 RGD:7771614

Term paths to the root
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Term Annotations click to browse term
  mammalian phenotype 5420
    cardiovascular system phenotype 1371
      abnormal cardiovascular system physiology 1148
        abnormal heartbeat 69
          abnormal heart rate 69
            abnormal sinus arrhythmia + 3
            decreased heart rate + 27
            increased heart rate + 40
paths to the root