increased circulating HDL cholesterol level - Ontology Report - Rat Genome Database

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MAMMALIAN PHENOTYPE - ANNOTATIONS	{{ watchLinkText }}
The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:	increased circulating HDL cholesterol level	go back to main search page
Accession:	MP:0001556	browse the term
Definition:	higher amount in the blood of the small lipoprotein:cholesterol complex that transports cholesterol out of the arteries and to the liver for reprocessing or excretion
Synonyms:	exact_synonym:	elevated HDL cholesterol level; elevated circulating HDL cholesterol level; high HDL cholesterol level; increased HDL cholesterol level
	narrow_synonym:	high HDL serum level
	alt_id:	MP:0000185; MP:0002617

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Genes (4) QTL (6) Strains (10)

increased circulating HDL cholesterol level

term browser

Symbol

Object Name

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

leptin

RGD

NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262

G

leptin; zinc finger nuclease induced mutant1, Sage

RGD

G

leptin receptor

RGD

NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908

G

leptin receptor; CRISPR/Cas9 induced mutant 4, Lizh

compared to wild type littermate

RGD

Term paths to the root

Path 1
Term	Annotations
mammalian phenotype	5373
homeostasis/metabolism phenotype	1397
abnormal homeostasis	1299
abnormal lipoprotein level	48
abnormal circulating lipoprotein level	48
abnormal circulating HDL cholesterol level	32
increased circulating HDL cholesterol level	20
Path 2
Term	Annotations
mammalian phenotype	5373
homeostasis/metabolism phenotype	1397
abnormal homeostasis	1299
abnormal lipid homeostasis	350
abnormal lipid level	345
abnormal sterol level	185
increased sterol level	150
increased cholesterol level	149
increased circulating cholesterol level	126
increased circulating HDL cholesterol level	20

paths to the root