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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:increased circulating HDL cholesterol level
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Accession:MP:0001556 term browser browse the term
Definition:higher amount in the blood of the small lipoprotein:cholesterol complex that transports cholesterol out of the arteries and to the liver for reprocessing or excretion
Synonyms:exact_synonym: elevated HDL cholesterol level;   elevated circulating HDL cholesterol level;   high HDL cholesterol level;   increased HDL cholesterol level
 narrow_synonym: high HDL serum level
 alt_id: MP:0000185;   MP:0002617



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increased circulating HDL cholesterol level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lep leptin IMP RGD PMID:22948215 RGD:12904911 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lepem1Sage leptin; zinc finger nuclease induced mutant1, Sage IMP RGD PMID:22948215 RGD:12904911
G Lepr leptin receptor IMP RGD PMID:26537785 RGD:12911216 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
G Leprem4Lizh leptin receptor; CRISPR/Cas9 induced mutant 4, Lizh IMP compared to wild type littermate RGD PMID:26537785 RGD:12911216

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5364
    homeostasis/metabolism phenotype 1389
      abnormal homeostasis 1295
        abnormal lipoprotein level 48
          abnormal circulating lipoprotein level 48
            abnormal circulating HDL cholesterol level 32
              increased circulating HDL cholesterol level 20
Path 2
Term Annotations click to browse term
  mammalian phenotype 5364
    homeostasis/metabolism phenotype 1389
      abnormal homeostasis 1295
        abnormal lipid homeostasis 350
          abnormal lipid level 345
            abnormal sterol level 185
              increased sterol level 150
                increased cholesterol level 149
                  increased circulating cholesterol level 126
                    increased circulating HDL cholesterol level 20
paths to the root