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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:increased circulating free fatty acids level
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Accession:MP:0001554 term browser browse the term
Definition:higher than normal levels of the fatty acids which occur in plasma as a result of lipolysis in adipose tissue or when plasma triacyglycerols are taken into tissues
Synonyms:exact_synonym: increased FFA level;   increased UFA level;   increased circulating free fatty acid level;   increased circulating non-esterified fatty acids level;   increased unesterified fatty acids level
 narrow_synonym: elevated serum free fatty acid levels
 related_synonym: increased NEFA level;   increased free fatty acids level


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increased circulating free fatty acids level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gck glucokinase IDA overexpression sufficient to lower blood glucose significantly increased circulating FFA and TG levels (p<0.05) RGD PMID:10512368 RGD:2301945 NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995 		JBrowse link
G Ldlr low density lipoprotein receptor IMP RGD PMID:28469073 RGD:12910100 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580 		JBrowse link
G Ldlrem1Sage low density lipoprotein receptor; ZFN induced mutant 1, Sage IMP RGD PMID:28469073 RGD:12910100
G Mc4r melanocortin 4 receptor IMP RGD PMID:24400148 RGD:13825242 NCBI chr18:60,419,832...60,421,719
Ensembl chr18:60,419,832...60,421,719 		JBrowse link
G Mc4rm1Hubr melanocortin 4 receptor; ENU induced mutation 1, Hubr IMP RGD PMID:24400148 RGD:13825242
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5402
    homeostasis/metabolism phenotype 1418
      abnormal homeostasis 1319
        abnormal blood homeostasis 760
          abnormal circulating lipid level 307
            abnormal circulating free fatty acids level 38
              increased circulating free fatty acids level 27
Path 2
Term Annotations click to browse term
  mammalian phenotype 5402
    homeostasis/metabolism phenotype 1418
      abnormal homeostasis 1319
        abnormal lipid homeostasis 361
          abnormal lipid level 356
            abnormal fatty acids level 44
              abnormal free fatty acids level 43
                abnormal circulating free fatty acids level 38
                  increased circulating free fatty acids level 27
paths to the root